Photo by Ryan Coleman

Find hotels in Sikeston, MO from AED 180

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Compare 247 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1005)
"Exceptionally nice property. A bit away from restaurants, etc., but dirveable."
The price is AED 231
AED 263 total
includes taxes & fees
25 Dec - 26 Dec
Days Inn and Suites by Wyndham Sikeston

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Estuvo bonito todo"
The price is AED 281
AED 323 total
includes taxes & fees
10 Jan - 11 January 2025
Pear Tree Inn Sikeston

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Everything was great about this property. We have stayed here several times and love the service and the people. "
The price is AED 364
AED 418 total
includes taxes & fees
27 Dec - 28 Dec
Drury Inn & Suites Sikeston, MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (611)
"Always a great place to stay, I won't stay anywhere else! Thank you."
The price is AED 230
AED 262 total
includes taxes & fees
23 Dec - 24 Dec
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1003)
"Not a bad hotel needs updated bathroom was not clean"
The price is AED 291
AED 332 total
includes taxes & fees
5 Jan - 6 January 2025
Best Western Plus Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (308)
"Good folks and clean hotel. Will stay again if back to visit family. "
The price is AED 426
AED 483 total
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn Sikeston

Country Yard Inn and Suite

2.0 star property
7.4 out of 10, Good, (62)
"Nice and clean place to stay for a reasonable cost."
The price is AED 180
AED 214 total
includes taxes & fees
3 Jan - 4 January 2025
Country Yard Inn and Suite

Dexter Inn

2.5 star property
7.0 out of 10, Good, (277)
"The breakfast was fresh but few choices. desk service excellent"
The price is AED 239
AED 268 total
includes taxes & fees
24 Dec - 25 Dec
Dexter Inn

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

2.5 star property
8.6 out of 10, Excellent, (381)
"Our first stay in this particular Motel. Everything was great! "
The price is AED 415
AED 470 total
includes taxes & fees
5 Jan - 6 January 2025
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (509)
"Excellent staff"
The price is AED 209
AED 239 total
includes taxes & fees
28 Dec - 29 Dec
Super 8 by Wyndham Sikeston/Miner Area

Hickory House Inn

2.5 star property
5.4 out of 10, (104)
"Nice place for the price."
The price is AED 202
AED 227 total
includes taxes & fees
23 Dec - 24 Dec
Hickory House Inn

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (229)
"We were happy with our stay "
The price is AED 328
AED 374 total
includes taxes & fees
10 Jan - 11 January 2025
Comfort Inn & Suites Sikeston I-55

Econo Lodge Dexter

2.0 star property
6.8 out of 10, (214)
"Typical hotel stay, some dingy lights and older carpet that smelled but it was clean and quiet. "
The price is AED 227
AED 255 total
includes taxes & fees
29 Dec - 30 Dec
Econo Lodge Dexter

Travelodge by Wyndham Dexter

2.0 star property
7.4 out of 10, Good, (348)
"The young woman who checked us in was wonderful. She was warm and gracious. The room was extremely clean and comfortable. My mother was with me, and she was disappointed to find there was no coffee in the room, nor were there any drinking glasses."
The price is AED 335
AED 376 total
includes taxes & fees
16 Jan - 17 January 2025
Travelodge by Wyndham Dexter

The Blue Door

10.0 out of 10, Exceptional, (1)
The price is AED 331
AED 404 total
includes taxes & fees
30 Dec - 31 Dec
The Blue Door

Dexter Homestead. Very Cozy & NEW Remodel !

8.4 out of 10, Very Good, (19)
"Plenty of room to move about. Quiet neighborhood. Host took care of all our needs."
The price is AED 364
AED 754 total
includes taxes & fees
23 Dec - 24 Dec
Dexter Homestead. Very Cozy & NEW Remodel !

Modern and Cozy Apartment with large windows and sunlight.

Modern and Cozy Apartment with large windows and sunlight.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Notting Hill Cottage: This vacation home rental outside of Sikeston offers a patio, a private yard, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a spa tub. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Kids of all ages will also enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

Favorite places to visit include The Book Bug, Boot Heel Golf Club, and Sikeston Depot Museum. Additionally, you might want to add Central Park to your itinerary. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.