Find hotels in Cairo, IL from AED 228

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Check prices for these dates

Tonight
16 Mar - 17 Mar
Tomorrow
17 Mar - 18 Mar
Next weekend
21 Mar - 23 Mar
In two weeks
28 Mar - 30 Mar

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Compare 24 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (247)
"Convenient"
The price is AED 294
AED 326 total
includes taxes & fees
20 Mar - 21 Mar
Quality Inn Cairo I-57
La Center Motel
Basic Double Room | Free WiFi

La Center Motel

2.0 star property
7.4 out of 10, Good, (12)
"Great place for hunters and what not close to Ballard and boat wright stay here several times and really don’t have no complaints "
The price is AED 239
AED 275 total
includes taxes & fees
18 Mar - 19 Mar
La Center Motel
Regency Inn
Reception

Regency Inn

2.0 star property
The price is AED 350
AED 389 total
includes taxes & fees
18 Mar - 19 Mar
Regency Inn
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (95)
"Comfortable bed, easy access to room"
The price is AED 234
AED 260 total
includes taxes & fees
18 Mar - 19 Mar
Eagle Inn Charleston
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (547)
"I was passing by and decided to take a break here. The bed was clean, had hot water and the heat was working. Took a quick 5 hour sleep and was back on the road. "
The price is AED 228
AED 253 total
includes taxes & fees
19 Mar - 20 Mar
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (372)
"Bathroom was dirty.. think dried pee on the toilet seat (thankful to have taken Clorox wipes) and brown ring in the bath tub. The floor on the sink area had not been swept. "
The price is AED 271
AED 301 total
includes taxes & fees
6 Apr - 7 Apr
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Cairo

Escape to quaint Cairo! Enjoy its ruins, history, and food.

See all hotels in Cairo

Frequently asked questions

Where is the best place for a stay in Cairo?

Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and Quality Inn Charleston - Sikeston. See all available top hotels, or vacation rentals in Cairo.

What are some of the best vacation rentals in Cairo?

Charming Home just minutes from Interstate and Mall: This vacation home rental near Cairo is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Cairo.

If I need to cancel my hotel reservation in Cairo, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.

Where can I learn more about changing or cancelling my trip to Cairo?

For more information about updating your trip to Cairo or cancelling it, head over to our customer service page.

Where is the best hotel to stay close to Fort Defiance?

Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.9 mi (7.8 km) from Fort Defiance. Other good options around the area include Victorian Splendor in So. Illinois: wallmanor.com and Eagle Inn Charleston.

What's the best hotel for staying near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Cairo like?

Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 24 hotels and other accommodations in the surrounding area. Find out more about Cairo.

What should I see while I'm in Cairo?

A couple of favorite places to visit are Mississippi River and Fort Defiance State Park. You'll also find Mound City National Cemetery and Columbus-Belmont State Park in the area. Check out what more to see and do in Expedia's Cairo guide.

What's the seasonal weather like in Cairo?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.