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Hotels near popular Sikeston Attractions
- Hotels near The Book Bug
- Hotels near Sikeston Depot Museum
- Hotels near Boot Heel Golf Club
- Hotels near Central Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
Sikeston Hotels by Star Rating
Explore more hotels
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Drury Inn & Suites Cape Girardeau
- Pear Tree Inn Cape Girardeau West
- Drury Plaza Hotel Cape Girardeau Conference Center
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Courtyard by Marriott Cape Girardeau Downtown
- The Riverview
- Quality Inn
- Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
- Hampton Inn Cape Girardeau I 55 East
- Holiday Inn Express & Suites Perryville, an IHG Hotel
- Hotel 7 Inn Anna
- Super 8 by Wyndham Perryville
- New cabin in the woods with private hot tub
- Comfort Suites Jackson-Cape Girardeau
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.
- Drury Inn & Suites Jackson MO
- Town House Inn