Photo by Ryan Coleman

Find Family Hotels in Sikeston, MO

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Check availability on Sikeston Family Hotels

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Compare Sikeston Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1067)
"Night time snacks were a perfect dinner option for us! Great breakfast to get us on the road for a long travel day. Very nice accommodations. "
The price is AED 364
AED 418 total
includes taxes & fees
13 Apr - 14 Apr
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1018)
"Very nice hotel. Except when we went to the hot tub, there was a bowel movement in the water. Didn't notice till we got out. Reported to hotel staff."
The price is AED 314
AED 361 total
includes taxes & fees
2 Apr - 3 Apr
Pear Tree Inn Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1058)
"It was a very late arrival and they were very accomodating. Friendly staff. Very good breakfast."
The price is AED 344
AED 392 total
includes taxes & fees
30 Mar - 31 Mar
Best Western Plus Sikeston

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (910)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."
The price is AED 347
AED 392 total
includes taxes & fees
27 Apr - 28 Apr
Drury Inn & Suites Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (692)
"Room looked great when we got there. There was a few things that needed attention. I left them a note."
The price is AED 356
AED 386 total
includes taxes & fees
30 Mar - 31 Mar
Comfort Suites Jackson-Cape Girardeau

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1043)
"The property was clean and quiet. The breakfast options were very good."
The price is AED 364
AED 384 total
includes taxes & fees
1 Apr - 2 Apr
Drury Inn & Suites Jackson MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1070)
"This hotel was clan and the staff was friendly. The workout room and the pool were small but clean. The staff were friendly."
The price is AED 378
AED 427 total
includes taxes & fees
6 Apr - 7 Apr
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Dexter Inn

2.5 star property
6.8 out of 10, (289)
"Quiet"
The price is AED 238
AED 268 total
includes taxes & fees
3 Apr - 4 Apr
Dexter Inn

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (374)
"Staff were very friendly. Room was spacious and well designed."
The price is AED 277
AED 307 total
includes taxes & fees
20 Apr - 21 Apr
Quality Inn Charleston - Sikeston

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1020)
"It was small room but was okay "
The price is AED 248
AED 280 total
includes taxes & fees
20 Apr - 21 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Sikeston like for family-friendly vacations?
The welcoming destination of Sikeston is a great choice if you’ve been considering a vacation with the kids. The excursions, museums, and cafes are just some of the things that make this an attractive family vacation spot. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city center.
What's the best place to stay for a family vacation in Sikeston?
Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it’s a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good option for your family trip.
How many family-friendly hotels should I expect to find in Sikeston?
Expedia has 16 hotels in Sikeston that are rated for being family-friendly.
When's the best time to book a family-friendly vacation in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do with your family in Sikeston?
While you are vacationing in Sikeston, you and the family might want to see interesting spots such as The Book Bug and Front Street Studio & Art Gallery. Make sure you have lots of time for activities like Big Oak Tree State Park and Shawnee National Forest.