Photo by Ryan Coleman

Find Family Hotels in Sikeston, MO

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Pick from 25 Sikeston Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Auburn Place Hotel And Suites
Indoor pool
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1005)
"Sorry that they tearing down this wonderful place"
Auburn Place Hotel And Suites
Drury Inn & Suites Sikeston, MO
Pool
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1001)
"Very impressed with the customer service!"
The price is AED 364
AED 418 total
includes taxes & fees
24 Nov - 25 Nov
Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Exterior
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1006)
"It was wonderful. As soon as I walked in I was met with amazing customer service. Check in was easy and quick, I actually arrived at noon and was able to check in early. Evening snacks were pretzels and assortment of chips, cheese dip and salsa. The wine was yummy. The breakfast was a hot breakfast buffet. The I ddor pool and hot tub were so clean and provided towels in the area. I will definitely stay again.thank you! "
The price is AED 297
AED 342 total
includes taxes & fees
22 Nov - 23 Nov
Pear Tree Inn Sikeston
Best Western Plus Sikeston
Exterior
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1002)
"Good hotel. Stains on light shade and lining of bed ripped on the bottom. "
The price is AED 314
AED 351 total
includes taxes & fees
17 Nov - 18 Nov
Best Western Plus Sikeston
Drury Inn & Suites Cape Girardeau
Exterior
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (813)
"Great"
The price is AED 314
AED 354 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Exterior
Comfort Suites Jackson-Cape Girardeau
2.5 star property
8.2 out of 10, Very Good, (668)
"Quiet and comfortable. Room had a few minor problems - brown stains on tub, torn upholstery - but these were minor. Breakfast was okay. Hard to find any staff but they were friendly when found. "
The price is AED 267
AED 286 total
includes taxes & fees
1 Dec - 2 Dec
Comfort Suites Jackson-Cape Girardeau
Drury Inn & Suites Jackson MO
Exterior
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (1003)
"Hotel was very clean and put together. All staff was incredibly friendly! Would definitely recommend and stay here again. "
The price is AED 331
AED 349 total
includes taxes & fees
21 Nov - 22 Nov
Drury Inn & Suites Jackson MO
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (1000)
"Our only complaint was the kids channels weren’t working on the TV. Other than that clean, quiet, polite, good eating area"
The price is AED 349
AED 387 total
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Dexter Inn
Outdoor pool
Dexter Inn
2.5 star property
7.0 out of 10, Good, (272)
"The breakfast was fresh but few choices. desk service excellent"
The price is AED 239
AED 263 total
includes taxes & fees
16 Nov - 17 Nov
Dexter Inn
Quality Inn Charleston - Sikeston
Exterior
Quality Inn Charleston - Sikeston
2.5 star property
6.8 out of 10, (358)
"Great bed. "
The price is AED 213
AED 230 total
includes taxes & fees
7 Dec - 8 Dec
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Sikeston like for family-friendly vacations?
The welcoming destination of Sikeston is a great choice if you’ve been considering a vacation with the kids. The excursions, museums, and cafes are just some of the things that make this an attractive family vacation spot. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city center.
What's the best place to stay for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it’s a top choice on Expedia for families. Pear Tree Inn Sikeston is another good option for your family trip.
How many family-friendly hotels should I expect to find in Sikeston?
Expedia has 16 hotels in Sikeston that are rated for being family-friendly.
When's the best time to book a family-friendly vacation in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do with your family in Sikeston?
While you are vacationing in Sikeston, you and the family might want to see interesting spots such as The Book Bug and Front Street Studio & Art Gallery. Make sure you have lots of time for activities like Central Park and Mississippi River.