Photo by Ryan Coleman

Find Family Hotels in Sikeston, MO

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Sikeston Family Hotels

This weekend
Next weekend

Compare Sikeston Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Great staff. Called you by your name and were super helpful. The room was very spacious and comfortable. The whole property was clean and well maintained. The breakfast was very tasty and ample with a nice attendant making sure everything was available."
The price is AED 364
AED 418 total
includes taxes & fees
4 May - 5 May
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Great experience! Nice clean hotel with many travelers on site. Safe and well lit parking lot."
The price is AED 314
AED 361 total
includes taxes & fees
4 May - 5 May
Pear Tree Inn Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1003)
"Room had an unsanitary smell. Staff was willing to move me to another room but it had same animal or dirty smell"
The price is AED 331
AED 377 total
includes taxes & fees
27 Apr - 28 Apr
Best Western Plus Sikeston

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (923)
"Excellent hotel! The evening dinner is a nice feature. The breakfast was very good. Overall I would recommend this hotel."
The price is AED 364
AED 410 total
includes taxes & fees
6 May - 7 May
Drury Inn & Suites Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (699)
"Big room on the corner!!"
The price is AED 356
AED 386 total
includes taxes & fees
27 Apr - 28 Apr
Comfort Suites Jackson-Cape Girardeau

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Pam who took care of the breakfast was so nice! Lovely place, clean, and great breakfast, definitely recommend!"
The price is AED 331
AED 349 total
includes taxes & fees
29 Apr - 30 Apr
Drury Inn & Suites Jackson MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1004)
"I chose this hotel because I stayed 8 months ago when I daughter was scheduled for a C-section and I was so happy with the staff, location of the property and condition of the room I had to return. "
The price is AED 378
AED 427 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Dexter Inn

2.5 star property
7.0 out of 10, Good, (291)
"Quiet"
The price is AED 233
AED 262 total
includes taxes & fees
27 Apr - 28 Apr
Dexter Inn

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (377)
"Customer service is what sets them apart."
The price is AED 261
AED 290 total
includes taxes & fees
2 May - 3 May
Quality Inn Charleston - Sikeston

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Very nice accommodating staff. "
The price is AED 215
AED 242 total
includes taxes & fees
29 Apr - 30 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Sikeston

Frequently asked questions

What's Sikeston like for family-friendly vacations?
The welcoming destination of Sikeston is a great choice if you’ve been considering a vacation with the kids. The excursions, museums, and cafes are just some of the things that make this an attractive family vacation spot. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city center.
What's the best place to stay for a family vacation in Sikeston?
Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it’s a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good option for your family trip.
How many family-friendly hotels should I expect to find in Sikeston?
Expedia has 16 hotels in Sikeston that are rated for being family-friendly.
When's the best time to book a family-friendly vacation in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do with your family in Sikeston?
While you are vacationing in Sikeston, you and the family might want to see interesting spots such as The Book Bug and Front Street Studio & Art Gallery. Make sure you have lots of time for activities like Central Park and Big Oak Tree State Park.