Find hotels in East Prairie, MO from AED 204

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Compare 80 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Union City by IHG

2.5 star property
9.2 out of 10, Wonderful, (257)
"Very nice and clean. Keurig coffee makers and Dove shampoo and soap, in the rooms. Warm indoor swimming. Nice breakfast with bacon, sausage, and biscuits. It is right next to the Discovery Museum. "
The price is AED 422
AED 502 total
includes taxes & fees
27 Apr - 28 Apr
Holiday Inn Express & Suites Union City by IHG

Country Hearth Inn & Suites Union City

2.5 star property
8.8 out of 10, Excellent, (512)
"A clean room at a decent price. The owners are friendly as well. I always stay at Country Hearth when I'm in the Union City, TN. area."
The price is AED 248
AED 294 total
includes taxes & fees
14 Apr - 15 Apr
Country Hearth Inn & Suites Union City

Hampton Inn Union City

2.5 star property
9.4 out of 10, Exceptional, (120)
"All was fine, thank you. We look forward to returning. "
The price is AED 432
AED 513 total
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn Union City

Sleep Inn

2.5 star property
9.0 out of 10, Wonderful, (227)
"All good!"
The price is AED 340
AED 404 total
includes taxes & fees
27 Apr - 28 Apr
Sleep Inn

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1002)
"The gentleman at the front desk was super nice , friendly and just fun when we checked in , we had a quick overnight stay in town ! Pool was clean nice and warm , the next morning breakfast was nice clean and stocked and the young lady cleaning and keeping it full was very friendly also , plus we were able to have are Yorkie in room at a reasonable charge "
The price is AED 315
AED 359 total
includes taxes & fees
17 Apr - 18 Apr
Best Western Plus Sikeston

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Excellent costumer service and very clean facility. This is my number one choice hotel while visiting family in Sikeston. Nice kick back dinner with great breakfast options. Well lighted parking lot! "
The price is AED 364
AED 418 total
includes taxes & fees
20 Apr - 21 Apr
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1006)
"This hotel is very comfortable clean and staff goes out of their way to be friendly!!!! I love staying at this hotel!"
The price is AED 314
AED 361 total
includes taxes & fees
15 Apr - 16 Apr
Pear Tree Inn Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (645)
"Easy check-in, clean queen non smoking room. Absolutely worth the price. The continental breakfast was weak. The oj machine serves orange water and the raisin bran was exceptionally old. So much so that the raisins were hard as pebbles; not kidding. "
The price is AED 277
AED 316 total
includes taxes & fees
13 Apr - 14 Apr
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Quality Inn Union City US 51

2.5 star property
8.4 out of 10, Very Good, (422)
"We were returning guests, and ha"
The price is AED 274
AED 326 total
includes taxes & fees
4 May - 5 May
Quality Inn Union City US 51

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (248)
"It was okay, quiet and helpful."
The price is AED 340
AED 388 total
includes taxes & fees
4 May - 5 May
Comfort Inn & Suites Sikeston I-55

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (329)
"Friendly staff, comfortable beds, spacious room (313). "
The price is AED 403
AED 456 total
includes taxes & fees
17 Apr - 18 Apr
Hampton Inn Sikeston

New Orleans Inn Portageville

2.5 star property
8.2 out of 10, Very Good, (645)
"Good "
The price is AED 204
AED 220 total
includes taxes & fees
13 Apr - 14 Apr
New Orleans Inn Portageville

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (400)
"Clean "
The price is AED 450
AED 510 total
includes taxes & fees
20 Apr - 21 Apr
Holiday Inn Express & Suites Sikeston Southwest by IHG

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"Very accommodating staff"
The price is AED 297
AED 338 total
includes taxes & fees
20 Apr - 21 Apr
Days Inn and Suites by Wyndham Sikeston

Super 8 By Wyndham Marston

2.0 star property
7.8 out of 10, Good, (16)
"It was ok with refurbished rooms. We had only one towel in the bathroom and had to get someone to fill up the soap dispenser. Not alot of good restaurants in the area."
The price is AED 301
AED 344 total
includes taxes & fees
12 Apr - 13 Apr
Super 8 By Wyndham Marston

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (375)
"Staff were very friendly. Room was spacious and well designed."
The price is AED 263
AED 292 total
includes taxes & fees
4 May - 5 May
Quality Inn Charleston - Sikeston

Hospitality House Union City US 51

2.5 star property
7.0 out of 10, Good, (284)
"It's just an older property that could use some upgrades. It was an ok stay and the staff was very nice. Breakfast was lacking."
The price is AED 205
AED 243 total
includes taxes & fees
11 May - 12 May
Hospitality House Union City US 51

Rosewood Inn By OYO Union City I-69

2.0 star property
4.4 out of 10, (103)
"Was really nice"
The price is AED 206
AED 268 total
includes taxes & fees
1 May - 2 May
Rosewood Inn By OYO Union City I-69
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about East Prairie

Explore attractions like Big Oak Tree State Park and Mississippi River as you discover things to see and do in East Prairie.

Frequently asked questions

What's the best place for a stay in East Prairie?

Pear Tree Inn Sikeston, located 11.4 mi (18.3 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Drury Inn & Suites Sikeston, MO and Best Western Plus Sikeston. See all available top hotels, or vacation rentals in East Prairie.

What are some of the best vacation rentals that East Prairie has to offer?

For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier: Visitors like this East Prairie vacation home rental. It is located on a lake and has a balcony, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in East Prairie.

If I need to cancel my hotel reservation in East Prairie, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.

Where can I learn more about changing or cancelling my trip to East Prairie?

To access more information about rescheduling or cancelling your trip to East Prairie, click here.

What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

What's it like to stay in East Prairie?

Visitors are sure to enjoy all that East Prairie has to offer. There are 30 hotels and other accommodations in the surrounding area. Find out more about East Prairie.

What should I do while I'm visiting East Prairie?

The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find The Book Bug and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.

What's the weather like in East Prairie?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.