Find hotels in East Prairie, MO from AED 204
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Compare 80 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
9.2 out of 10, Wonderful, (257)
The price is AED 422
AED 502 total
includes taxes & fees
27 Apr - 28 Apr

Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union City
8.8 out of 10, Excellent, (512)
The price is AED 248
AED 294 total
includes taxes & fees
14 Apr - 15 Apr

Hampton Inn Union City
Hampton Inn Union City
9.4 out of 10, Exceptional, (120)
The price is AED 432
AED 513 total
includes taxes & fees
20 Apr - 21 Apr

Sleep Inn
Sleep Inn
9.0 out of 10, Wonderful, (227)
The price is AED 340
AED 404 total
includes taxes & fees
27 Apr - 28 Apr

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1002)
The price is AED 315
AED 359 total
includes taxes & fees
17 Apr - 18 Apr

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1001)
The price is AED 364
AED 418 total
includes taxes & fees
20 Apr - 21 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about East Prairie
Explore attractions like Big Oak Tree State Park and Mississippi River as you discover things to see and do in East Prairie.
More cheap stays in East Prairie
More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is AED 297 per night from Apr 20 to Apr 21
AED 297
AED 338 total
includes taxes & fees
20 Apr - 21 Apr
7.2/10 Good! (992 reviews)
Hotels in East Prairie with star-rating
Hotels in East Prairie with star-rating

3 Star Hotels
3 properties

2 Star Hotels
28 properties
Stay near popular East Prairie attractions
Stay near popular East Prairie attractions
Big Oak Tree State Park
4.5/5(3 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
Recent reviews of East Prairie hotels
Recent reviews of East Prairie hotels

Pear Tree Inn Sikeston
5/5 Excellent
"This hotel is very comfortable clean and staff goes out of their way to be friendly!!!! I love staying at this hotel!"
A verified traveler stayed at Pear Tree Inn Sikeston
Posted 19 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Stay near popular East Prairie attractions
- Hotels near Big Oak Tree State Park
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Reelfoot Lake State Park
- Hotels near Discovery Park of America
- Hotels near Columbus-Belmont State Park
- Hotels near Union City Masquerade Theatre
- Hotels near The Book Bug
- Hotels near Campbell's Point
- Hotels near Fort Defiance State Park
- Hotels near New Madrid Historical Museum
- Hotels near Marston Community Center
- Hotels near Central Park
- Hotels near Graham Park
- Hotels near Sikeston Depot Museum
- Hotels near River Ridge Winery
More Accommodation Types in East Prairie
East Prairie Hotels by Brand
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Explore more hotels
- For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier
- Quality Inn Union City US 51
- Country Yard Inn and Suite
- Country Hearth Inn & Suites Union City
- Comfort Inn & Suites Sikeston I-55
- Sleep Inn
- Super 8 By Wyndham Marston
- Super 8 by Wyndham Charleston/Sikeston East MO
- Hampton Inn Union City
- Quality Inn Charleston - Sikeston
- Lake House scales and duck
- Lakeside View Lodge overlooking beautiful Reelfoot Lake