Photo by Ryan Coleman
Find all hotels by Independent in Sikeston, MO from AED 231
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Compare rooms and suites by Independent in Sikeston with rates, reviews, and availability. Most hotels are fully refundable.

The Riverview
The Riverview
9.2 out of 10, Wonderful, (225)
The price is AED 356
AED 402 total
includes taxes & fees
14 Apr - 15 Apr

Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
6.0 out of 10, (178)
The price is AED 231
AED 270 total
includes taxes & fees
14 Apr - 15 Apr

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very Good, (645)
The price is AED 247
AED 281 total
includes taxes & fees
14 Apr - 15 Apr

Hotel 7 Inn Anna
Hotel 7 Inn Anna
6.6 out of 10, (197)
The price is AED 247
AED 274 total
includes taxes & fees
14 Apr - 15 Apr

Town House Inn
Town House Inn
7.8 out of 10, Good, (393)

Bullwinkles Rustic Lodge
Bullwinkles Rustic Lodge
8.6 out of 10, Excellent, (204)

Country Yard Inn and Suite
Country Yard Inn and Suite
7.0 out of 10, Good, (86)
The price is AED 236
AED 281 total
includes taxes & fees
14 Apr - 15 Apr

Dexter Inn
Dexter Inn
7.0 out of 10, Good, (290)
The price is AED 248
AED 279 total
includes taxes & fees
15 Apr - 16 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Sikeston hotels
Recent reviews of Sikeston hotels

Pear Tree Inn Cape Girardeau Near the Medical Center
5/5 Excellent
"Absolutely wonderful friendly people great location very clean! I love it "
A verified traveler stayed at Pear Tree Inn Cape Girardeau Near the Medical Center
Posted 17 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Sikeston Hotels by Brand
Hotels near popular Sikeston Attractions
- Hotels near The Book Bug
- Hotels near Central Park
- Hotels near Sikeston Depot Museum
- Hotels near Boot Heel Golf Club
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
More Hotel Options in Sikeston
- Adults Only Resorts & Hotels in Sikeston
- Adventure Hotels in Sikeston
- Business Hotels in Sikeston
- Casinos in Sikeston
- Cheap Hotels in Sikeston
- Family Hotels in Sikeston
- Golf Hotels in Sikeston
- Historic Hotels in Sikeston
- Hotel Wedding Venues in Sikeston
- Hotels with Bars in Sikeston
- Hotels with Free Parking in Sikeston
- Hotels with Hot Tubs in Sikeston
- Hotels with WiFi in Sikeston
- Hotels with a Pool in Sikeston
- Hotels with an Indoor Pool in Sikeston
- Hotels with smoking rooms in Sikeston
- Luxury Hotels in Sikeston
- Pet-friendly Hotels in Sikeston
- Resorts & Hotels with Spas in Sikeston
- Romantic Hotels in Sikeston
- Shopping Hotels in Sikeston
- Winery Hotels in Sikeston
More Accommodation Types in Sikeston
Explore more hotels
- TownePlace Suites by Marriott Sikeston
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Drury Inn & Suites Cape Girardeau
- Pear Tree Inn Cape Girardeau West
- Candlewood Suites Cape Girardeau by IHG
- Super 8 by Wyndham Perryville
- Quality Inn
- Drury Inn & Suites Jackson MO
- Courtyard by Marriott Cape Girardeau Downtown
- Town House Inn Cape Giradreau
- Tru By Hilton Cape Girardeau
- Hampton Inn Cape Girardeau I 55 East
- Holiday Inn Express & Suites Perryville by IHG
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Comfort Suites Jackson-Cape Girardeau