Photo by Ryan Coleman
Find 2 Star Hotels in Sikeston, MO from AED 231
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Sikeston 2 Star Hotels
Compare Sikeston 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1002)
The price is AED 281
AED 320 total
includes taxes & fees
13 Apr - 14 Apr

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1002)
The price is AED 378
AED 427 total
includes taxes & fees
4 May - 5 May

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
9.0 out of 10, Wonderful, (528)
The price is AED 306
AED 331 total
includes taxes & fees
13 Apr - 14 Apr

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1008)
The price is AED 314
AED 361 total
includes taxes & fees
13 Apr - 14 Apr

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1007)
The price is AED 264
AED 298 total
includes taxes & fees
5 May - 6 May

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1004)
The price is AED 315
AED 359 total
includes taxes & fees
15 Apr - 16 Apr

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
8.2 out of 10, Very Good, (760)
The price is AED 301
AED 360 total
includes taxes & fees
4 May - 5 May

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
9.4 out of 10, Exceptional, (420)
The price is AED 342
AED 379 total
includes taxes & fees
20 Apr - 21 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Sikeston.

The Riverview
777 Main St, Cape Girardeau, MO
The price is AED 354 per night from Apr 21 to Apr 22
AED 354
AED 399 total
includes taxes & fees
21 Apr - 22 Apr
9.2/10 Wonderful! (211 reviews)
Still don't see what you're looking for?
See all properties in Sikeston.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston and related destinations
Explore Sikeston: its food, riverfront, university life, and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman
Explore the historic buildings and museums of this delightful South Carolina city that’s also known for its nature trails and outdoor pursuits.

Once a Mexican migrant settlement, this Californian town is located on the edge of one of the most important wetland regions in North America.

Photo by Jess. LongestBusRide
Open Photo by Jess. LongestBusRide
Experience romantic Olive Branch: its food, entertainment, live music, and more!
Lima awaits: its university life, food, cathedral, and more!

Photo by throwingsofas
Open Photo by throwingsofas
Recent reviews of Sikeston hotels
Recent reviews of Sikeston hotels

Super 8 by Wyndham Sikeston/Miner Area
5/5 Excellent
"Amazing "
A verified traveler stayed at Super 8 by Wyndham Sikeston/Miner Area
Posted 4 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Sikeston Hotels by Star Rating
Stay near popular Sikeston attractions
- Hotels near The Book Bug
- Hotels near Central Park
- Hotels near Sikeston Depot Museum
- Hotels near Boot Heel Golf Club
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
- Hotels near Big Oak Tree State Park
- Hotels near The Heritage House
- Hotels near Mound City National Cemetery
- Hotels near eDen Spa & Salon
- Hotels near Fort D Historic Site
- Hotels near New Madrid Historical Museum
- Hotels near Marston Community Center
- Hotels near Fort Defiance State Park
- Hotels near River Ridge Winery
- Hotels near Stoddard County Civil War Memorial Cemetery
More Hotel Options in Sikeston
- Adults Only Resorts & Hotels in Sikeston
- Adventure Hotels in Sikeston
- Business Hotels in Sikeston
- Casinos in Sikeston
- Cheap Hotels in Sikeston
- Family Hotels in Sikeston
- Golf Hotels in Sikeston
- Historic Hotels in Sikeston
- Hotel Wedding Venues in Sikeston
- Hotels with Bars in Sikeston
- Hotels with Free Parking in Sikeston
- Hotels with Hot Tubs in Sikeston
- Hotels with WiFi in Sikeston
- Hotels with a Pool in Sikeston
- Hotels with an Indoor Pool in Sikeston
- Hotels with smoking rooms in Sikeston
- Luxury Hotels in Sikeston
- Pet-friendly Hotels in Sikeston
- Resorts & Hotels with Spas in Sikeston
- Romantic Hotels in Sikeston
- Shopping Hotels in Sikeston
- Winery Hotels in Sikeston
Explore more hotels
- TownePlace Suites by Marriott Sikeston
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Pear Tree Inn Cape Girardeau West
- Drury Inn & Suites Cape Girardeau
- Candlewood Suites Cape Girardeau by IHG
- Super 8 by Wyndham Perryville
- Quality Inn
- Drury Inn & Suites Jackson MO
- Courtyard by Marriott Cape Girardeau Downtown
- Town House Inn Cape Giradreau
- Tru By Hilton Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Hampton Inn Cape Girardeau I 55 East
- Holiday Inn Express & Suites Perryville by IHG
- Comfort Suites Jackson-Cape Girardeau