Find hotels in Southeast Missouri, MO from AED 191
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![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/91be33e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1000)
The price is AED 364
AED 410 total
includes taxes & fees
23 Feb - 24 Feb
![Exterior](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/8b122520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff
9.4 out of 10, Exceptional, (690)
The price is AED 356
AED 402 total
includes taxes & fees
21 Feb - 22 Feb
![Exterior](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/363ef183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
The Riverview
The Riverview
9.2 out of 10, Wonderful, (149)
The price is AED 356
AED 402 total
includes taxes & fees
17 Feb - 18 Feb
![Pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/81fbb6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (688)
The price is AED 403
AED 454 total
includes taxes & fees
23 Feb - 24 Feb
![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/50bc83ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
9.6 out of 10, Exceptional, (396)
The price is AED 434
AED 492 total
includes taxes & fees
23 Feb - 24 Feb
![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
8.6 out of 10, Excellent, (393)
The price is AED 450
AED 510 total
includes taxes & fees
23 Feb - 24 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.
![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=899&h=541&p=1&q=high)
More cheap stays in Southeast Missouri
More cheap stays in Southeast Missouri
![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f23ff087_y.jpg?impolicy=resizecrop&rw=402&ra=fit)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is AED 234 per night from Feb 23 to Feb 24
AED 234
AED 267 total
includes taxes & fees
23 Feb - 24 Feb
7.2/10 Good! (1,001 reviews)
Hotels in Southeast Missouri with star-rating
Hotels in Southeast Missouri with star-rating
![4 Star Hotels](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae_w.jpg)
4 Star Hotels
2 properties
Stay near popular Southeast Missouri attractions
Stay near popular Southeast Missouri attractions
![Taum Sauk Mountain in located in the St.Francis mountain range of south/central Missouri. It's also the highest point in Missouri. My kids are standing at the spot where the actual marker sign in](https://mediaim.expedia.com/destination/2/86e50eabc9d5592586815e7688be64ef.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Elephant Rocks State Park
5/5(13 reviews)
Explore the great outdoors at Elephant Rocks State Park, a lovely green space in Ironton. Make some time to visit the shops while you're in the area.
Recent reviews of Southeast Missouri hotels
Recent reviews of Southeast Missouri hotels
![Drury Plaza Hotel Cape Girardeau Conference Center](http://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)
Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"The staff have great customer service and very welcoming. "
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Hotels near Elephant Rocks State Park
- Hotels near Johnson's Shut-ins State Park
- Hotels near Southeast Missouri State University
- Hotels near Lake Wappapello
- Hotels near Ozark National Scenic Riverways
- Hotels near Echo Bluff State Park
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
- Hotels near Big Spring
- Hotels near Alley Spring & Mill
- Hotels near Taum Sauk Mountain State Park
- Hotels near Riverfront Bridge Park
- Hotels near Current River State Park
- Hotels near Black River Coliseum
- Hotels near Crown Valley Winery
- Hotels near Sainte Genevieve Winery
- Hotels near Trail of Tears State Park
- Hotels near Bonne Terre Mine
- Hotels near St. Joe State Park
- Hotels near Pickle Springs Natural Area
More Hotel Options in Southeast Missouri
- Adults Only Resorts & Hotels in Southeast Missouri
- Adventure Hotels in Southeast Missouri
- Business Hotels in Southeast Missouri
- Casinos in Southeast Missouri
- Cheap Hotels in Southeast Missouri
- Family Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Historic Hotels in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Hotel with a Concierge in Southeast Missouri
- Hotels with Bars in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Waterslides in Southeast Missouri
- Hotels with WiFi in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Resorts & Hotels with Spas in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Shopping Hotels in Southeast Missouri
- Ski Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
More Accommodation Types in Southeast Missouri
- Vacation Homes in Southeast Missouri
- Cabin Rentals in Southeast Missouri
- Cottages in Southeast Missouri
- Apartments in Southeast Missouri
- Motels in Southeast Missouri
- Farmstay in Southeast Missouri
- RV Parks in Southeast Missouri
- Condo Rentals in Southeast Missouri
- Lodges in Southeast Missouri
- Aparthotels in Southeast Missouri
- B&B in Southeast Missouri
- Villas in Southeast Missouri
Hotels near Southeast Missouri Airports
Southeast Missouri Hotels by Brand
Other Hotels near Southeast Missouri, Missouri
- Cape Girardeau Hotels
- Chesterfield Hotels
- Carbondale Hotels
- Southeastern United States Hotels
- Poplar Bluff Hotels
- Eminence Hotels
- Ozarks Hotels
- Sikeston Hotels
- Ste Genevieve Hotels
- Richmond Heights Hotels
- Fenton Hotels
- Wildwood Hotels
- Farmington Hotels
- Southern Illinois Hotels
- Anna Hotels
- Kirkwood Hotels
- Arnold Hotels
- Brentwood Hotels
- Dyersburg Hotels
- Eureka Hotels
Explore more hotels
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Courtyard by Marriott Cape Girardeau Downtown
- Pear Tree Inn Sikeston
- Fairfield Inn & Suites by Marriott Poplar Bluff
- New Orleans Inn Portageville
- Drury Inn & Suites Sikeston, MO
- Pear Tree Inn Cape Girardeau Near the Medical Center
- The Farmstead Hotel
- Quality Inn
- Drury Inn & Suites Jackson MO
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel