Photo by Ryan Coleman
Find All Sikeston Hotels
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Find All Sikeston Hotels
We have found 255 Sikeston Hotels
- Days Inn and Suites by Wyndham Sikeston
- Pear Tree Inn Sikeston
- Drury Inn & Suites Sikeston, MO
- Best Western Plus Sikeston
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Hampton Inn Sikeston
- Comfort Inn & Suites Sikeston I-55
- Country Yard Inn and Suite
- Super 8 by Wyndham Sikeston/Miner Area
- TownePlace Suites by Marriott Sikeston
- Fairfield by Marriott Inn & Suites Sikeston
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Pear Tree Inn Cape Girardeau West
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Candlewood Suites Cape Girardeau by IHG
- Courtyard by Marriott Cape Girardeau Downtown
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Quality Inn
- Drury Inn & Suites Jackson MO
- Holiday Inn Express & Suites Perryville by IHG
- Hampton Inn Cape Girardeau I 55 East
- Town House Inn Cape Giradreau
- Super 8 by Wyndham Perryville
- Town House Inn
- Bullwinkles Rustic Lodge
- Hotel 7 Inn Anna
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Comfort Suites Jackson-Cape Girardeau
- Super 8 by Wyndham Charleston/Sikeston East MO
- Dexter Inn
- Econo Lodge Dexter
- Quality Inn Perryville I-55
- Days Inn by Wyndham Perryville
- Travelodge by Wyndham Dexter
- NEW property! Lakeside covered hot tub, A-frame 3 King Beds, Shawnee Forest
- Quality Inn Charleston - Sikeston
- Hickory House Inn
- Rockwood Inn
- Davie School Inn
- EC Reed's Mercantile and Hotel
- Tru By Hilton Cape Girardeau
- Regency Inn
- The Weber Farm - Enjoy a beautiful 100 acre farm!
- Quality Inn Cairo I-57
- Makanda Inn
- Eagle Inn Charleston
- Outdoorsman Paradise
- Nanny's Place -In Heart of Wine Trail/Hiking. Winter Special Rate Dec 1 -Feb 27
- Giant City Lodge
- Beautifully Renovated Farmhouse in Jackson, MO
- La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau
- SOLAR ECLIPSE! Lodge on10ac open field. 4 bed, 1 bath. Family/Pet friendly
- OYO Malden Airport Inn
- Charming 1-bedroom B&B with AC, WiFi in historic Cape Girardeau