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Find hotels in Cape Girardeau, MO from AED 231

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Compare 156 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1001)
"We stay here several times a year and it’s always a wonderful time. All of the staff go above and beyond and we are always very comfortable "
The price is AED 347
AED 392 total
includes taxes & fees
15 Apr - 16 Apr
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (917)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, all was good. Oh yeah the dinner & breakfast was great the place was clean and our room was fantastic. Value was excellent. Allen B."
The price is AED 347
AED 392 total
includes taxes & fees
18 Apr - 19 Apr
Drury Inn & Suites Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (408)
"Amazing "
The price is AED 459
AED 520 total
includes taxes & fees
11 May - 12 May
Courtyard by Marriott Cape Girardeau Downtown

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (222)
"Very nice place "
The price is AED 356
AED 402 total
includes taxes & fees
14 Apr - 15 Apr
The Riverview

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (97)
"Great place"
The price is AED 342
AED 385 total
includes taxes & fees
4 May - 5 May
Fairfield Inn & Suites by Marriott Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (700)
"It was clean and the beds were actually very comfortable. They never refilled the conditioner in the shower but that was the only complaint. "
The price is AED 408
AED 460 total
includes taxes & fees
18 Apr - 19 Apr
Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1004)
"It was small room but was okay "
The price is AED 248
AED 280 total
includes taxes & fees
15 Apr - 16 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Will definitely stay there again!!"
The price is AED 378
AED 427 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Nicr"
The price is AED 264
AED 298 total
includes taxes & fees
15 Apr - 16 Apr
Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (762)
"Very nice place to stay and friendly people"
The price is AED 301
AED 360 total
includes taxes & fees
27 Apr - 28 Apr
Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

2.5 star property
9.8 out of 10, Exceptional, (6)
"New hotel. very nice."
The price is AED 372
AED 423 total
includes taxes & fees
4 May - 5 May
Tru By Hilton Cape Girardeau

Quality Inn

2.5 star property
7.0 out of 10, Good, (562)
"It was okay"
The price is AED 258
AED 291 total
includes taxes & fees
23 Apr - 24 Apr
Quality Inn

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (178)
"NA"
The price is AED 231
AED 270 total
includes taxes & fees
13 Apr - 14 Apr
Town House Inn Cape Giradreau

Rockwood Inn

2.0 star property
9.8 out of 10, Exceptional, (6)
"Had a wonderful stay at the Rockwood Inn and ready booked additional stay. Perfect location to stay at for football games or any other SEMO event! "
The price is AED 552
AED 623 total
includes taxes & fees
24 Apr - 25 Apr
Rockwood Inn

Davie School Inn

4.0 star property
10.0 out of 10, Exceptional, (47)
"A very unique place to stay, fun to look around at all the old school items!! The room was unique and very spacious.. great bed and hostess!!! Very walkable to restaurants and stores.. "
The price is AED 567
AED 630 total
includes taxes & fees
12 Apr - 13 Apr
Davie School Inn

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Very accommodating and friendly staff! Helpful with stressful travelers😊 Great breakfast and evening kick back snacks and drinks!"
The price is AED 331
AED 349 total
includes taxes & fees
14 Apr - 15 Apr
Drury Inn & Suites Jackson MO

EC Reed's Mercantile and Hotel

3.0 star property
9.6 out of 10, Exceptional, (68)
"EC Reed had the nicest, most attentive staff of anywhere I have ever stayed. The room was very clean. The experience was very unique."
The price is AED 429
AED 467 total
includes taxes & fees
13 Apr - 14 Apr
EC Reed's Mercantile and Hotel

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
9.0 out of 10, Wonderful, (530)
"Nice"
The price is AED 309
AED 335 total
includes taxes & fees
13 Apr - 14 Apr
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Makanda Inn

3.5 star property
10.0 out of 10, Exceptional, (29)
"This visit was a time of reset that I needed after loosing my mom. I could not have found a better place of peace to do just that. The calm that surrounded me was nothing short of a little piece of heaven where mom has finally reached in full splendor 😇 The room was exceptional, along with the beauty of the wood working of the lodge, the patio area and wrap around porch along the wood line is beautiful. Rather your looking for a time to just be still or a couples retreat or a family getaway I...
The price is AED 1,023
AED 1,167 total
includes taxes & fees
16 Apr - 17 Apr
Makanda Inn

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (697)
"V"
The price is AED 356
AED 386 total
includes taxes & fees
13 Apr - 14 Apr
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Cape Girardeau

Trip time! Discover the riverfront, history, and local cuisine in Cape Girardeau.

The Bar - this was one location Gone Girl was filmed at!
Photo by Skyy
Open Photo by Skyy

Frequently asked questions

What's the best place to stay in Cape Girardeau?

Courtyard by Marriott Cape Girardeau Downtown is a favorite property for Expedia customers. This hotel is a short 6-minute walk from Mississippi River, and it offers a restaurant and free parking. Other favorite options based on traveler reviews include The Riverview and Hampton Inn Cape Girardeau I 55 East. See all available top hotels, or vacation rentals in Cape Girardeau.

What are some of the best vacation home rentals in Cape Girardeau?

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool: This highly rated vacation home rental in Cape Girardeau is located in a rural location and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation. Other favorite homes for rent in Cape Girardeau are Serenity South -- Gardens, River-Views, and Refreshing Space and 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More. See all vacation rentals in Cape Girardeau.

If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?

Yes, the majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.

Where can I learn more about changing or cancelling my trip to Cape Girardeau?

For more details about picking new dates or cancelling your trip to Cape Girardeau, head over to our customer service page.

What's the best budget-friendly accommodation in Cape Girardeau?

Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travelers who want a more economical choice, and features free continental breakfast and free WiFi. Another top option for your stay on the cheap is Pear Tree Inn Cape Girardeau Near the Medical Center. View all budget hotels in Cape Girardeau.

What's the best hotel for families in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other good choices to stay with the kids include Pear Tree Inn Cape Girardeau West and Pear Tree Inn Cape Girardeau Near the Medical Center. Attractions like Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also fun for kids of all ages. Find more child-friendly accommodations in Cape Girardeau.

What is the top LGBTQ-friendly place to stay in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG and Candlewood Suites Cape Girardeau by IHG are two other good options for your trip.

What's the best pet-friendly hotel in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good choices to stay with your pet include Candlewood Suites Cape Girardeau by IHG and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.

Where is the best hotel to stay with easy access to Southeast Missouri State University?

Courtyard by Marriott Cape Girardeau Downtown is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers a restaurant and free parking. It's located just a short 0.8 mi (1.3 km) from Southeast Missouri State University. Other good choices within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West.

What about the best place to stay close to Show Me Center?

One of the top choices for your stay is Courtyard by Marriott Cape Girardeau Downtown, located a short 1 mi (1.6 km) from Show Me Center, and this 3-star hotel offers a restaurant and free parking. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options within a few miles.

What are some accommodations with pools in Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa, and free WiFi. View all hotels with pools in Cape Girardeau.

What is the best spa hotel in Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Cape Girardeau.

What's the best place to stay near Cape Girardeau Municipal Airport (CGI)?

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

What is staying in Cape Girardeau like?

History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting, and shopping. In Cape Girardeau, there are 58 hotels and other accommodations to choose from. Find out more about Cape Girardeau.

What are the top places to visit in Cape Girardeau?

Families come for attractions such as Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center, and Lazy L Safari Park. Natural beauty is on display at Cape Rock Park, Shawnee National Forest, and Mississippi River. The university setting is a highlight and Southeast Missouri State University is worth a campus tour. Check out what more to see and do in Expedia's Cape Girardeau guide.

What's the weather like in Cape Girardeau?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.