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Find hotels in Cape Girardeau, MO from AED 220
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Compare 153 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1003)
The price is AED 347
AED 391 total
includes taxes & fees
31 Mar - 1 Apr

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1002)
The price is AED 364
AED 410 total
includes taxes & fees
23 Mar - 24 Mar

The Riverview
The Riverview
9.2 out of 10, Wonderful, (173)
The price is AED 311
AED 351 total
includes taxes & fees
27 Mar - 28 Mar

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1003)
The price is AED 248
AED 280 total
includes taxes & fees
25 Mar - 26 Mar

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
9.4 out of 10, Exceptional, (91)
The price is AED 342
AED 385 total
includes taxes & fees
27 Mar - 28 Mar

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
8.2 out of 10, Very Good, (741)
The price is AED 286
AED 343 total
includes taxes & fees
30 Mar - 31 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Cape Girardeau
Trip time! Discover the riverfront, history, and university life in Cape Girardeau.

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More cheap stays in Cape Girardeau
More cheap stays in Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
The price is AED 364 per night from Mar 23 to Mar 24
AED 364
AED 410 total
includes taxes & fees
23 Mar - 24 Mar
9.4/10 Exceptional! (999 reviews)
Stay near popular Cape Girardeau attractions
Stay near popular Cape Girardeau attractions
Southeast Missouri State University
4.5/5(76 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Recent reviews of Cape Girardeau hotels
Recent reviews of Cape Girardeau hotels

Hampton Inn Cape Girardeau I 55 East
5/5 Excellent
"family trip to Cape G. This Hampton Inn is right off I-55 and also right off the roads to downtown Cape G. Plenty of places to eat and walk the dogs"
A verified traveler stayed at Hampton Inn Cape Girardeau I 55 East
Posted 2 days ago
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Stay near popular Cape Girardeau attractions
- Hotels near Southeast Missouri State University
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Cape Rock Park
- Hotels near Hunter Valley Winery
- Hotels near Riverfront Park
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Lazy L Safari Park
- Hotels near eDen Spa & Salon
- Hotels near Fort D Historic Site
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Giant City State Park
- Hotels near Trail of Tears State Park
- Hotels near Stone Creek Golf Club and Resort
- Hotels near StarView Vineyards
- Hotels near Bollinger Mill State Historic Site
- Hotels near Pomona Winery
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- Hotel Wedding Venues in Cape Girardeau
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Hotels near Cape Girardeau Airports
Cape Girardeau Hotels by Brand
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Explore more hotels
- Hampton Inn Cape Girardeau I 55 East
- Town House Inn Cape Giradreau
- Serenity South -- Gardens, River-Views, and Refreshing Space
- 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
- Rockwood Inn
- Tru By Hilton Cape Girardeau
- The Twisted Sassafras Treehouse
- "Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
- Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
- 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
- Loft Apartment Across From Semo University Houch Field House. Walk To Events
- Charming Secluded Getaway Cabin within minutes of amenities