Find Resorts & Hotels with Spas in Key West, FL

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Pick from 65 Key West Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Oceans Edge Key West Resort, Hotel & Marina
Pool
Oceans Edge Key West Resort, Hotel & Marina
4.0 star property
8.8 out of 10, Excellent, (1499)
"I thoroughly enjoyed my stay at oceans edge. I like how it is quaint and relaxing. On the other hand, the shuttle makes it easy to go downtown where all the business is happening. When i return to Key West i plan to stay with Oceans Edge."
The price is AED 659
AED 955 total
includes taxes & fees
1 Dec - 2 Dec
Oceans Edge Key West Resort, Hotel & Marina
Pier House Resort & Spa
Beach
Pier House Resort & Spa
4.0 star property
9.0 out of 10, Wonderful, (1006)
"The Location was excellent! Everyone here was very knowledgeable, nice, and helpful! This place had everything you need! Restaurants, bars, pool, spa, and a private beach, And it was close and walkable to many restaurants, historical sites, retail shops, music, and more! We look forward to staying here again! "
The price is AED 846
AED 1,183 total
includes taxes & fees
1 Dec - 2 Dec
Pier House Resort & Spa
Parrot Key Hotel & Villas
Front of property
Parrot Key Hotel & Villas
4.0 star property
8.8 out of 10, Excellent, (1009)
"Parrot Key Hotel is such a beautiful property. It has a lush tropical feel with 4 gorgeous pools. My week there was so relaxing. "
The price is AED 644
AED 922 total
includes taxes & fees
1 Dec - 2 Dec
Parrot Key Hotel & Villas
Amsterdam's Curry Mansion Inn
Front of property
Amsterdam's Curry Mansion Inn
3.0 star property
8.6 out of 10, Excellent, (813)
"Location is great. Cute little pool. Nice bathrooms ( although vent fans are needed) Check in was convenient "
The price is AED 691
AED 1,133 total
includes taxes & fees
22 Nov - 23 Nov
Amsterdam's Curry Mansion Inn
Hyatt Centric Key West Resort and Spa
Exterior
Hyatt Centric Key West Resort and Spa
4.0 star property
9.0 out of 10, Wonderful, (1001)
"Great place! Will stay again"
The price is AED 1,514
AED 1,913 total
includes taxes & fees
24 Nov - 25 Nov
Hyatt Centric Key West Resort and Spa
The Grand Guesthouse
Property grounds
The Grand Guesthouse
2.5 star property
9.6 out of 10, Exceptional, (963)
"Awesome staff and a great place to stay in KW"
The price is AED 509
AED 653 total
includes taxes & fees
28 Nov - 29 Nov
The Grand Guesthouse
Paradise Inn Key West - Adults Only
Outdoor pool
Paradise Inn Key West - Adults Only
3.5 star property
9.2 out of 10, Wonderful, (1000)
"Great location. Quiet but quick walk to Duval.. Health food and cvs near by "
The price is AED 988
AED 1,255 total
includes taxes & fees
22 Nov - 23 Nov
Paradise Inn Key West - Adults Only
Hampton Inn Key West FL
Pool
Hampton Inn Key West FL
2.5 star property
9.0 out of 10, Wonderful, (1130)
"Other than the battery dying on our door lock we had a great time! Beautiful pool and quiet location "
The price is AED 694
AED 905 total
includes taxes & fees
1 Dec - 2 Dec
Hampton Inn Key West FL
Southernmost Beach Resort
Exterior
Southernmost Beach Resort
4.0 star property
8.6 out of 10, Excellent, (2181)
"I loved this place. They tried to do anything we asked and smiled about it. We will be back."
The price is AED 893
AED 1,235 total
includes taxes & fees
17 Dec - 18 Dec
Southernmost Beach Resort
Simonton Court Historic Inn & Cottages
Exterior detail
Simonton Court Historic Inn & Cottages
2.5 star property
9.8 out of 10, Exceptional, (665)
"It’s in a great location it was so easy to walk to restaurants, shops and activities. The continental breakfast by the pool was really good and the staff was very friendly."
The price is AED 1,061
AED 1,175 total
includes taxes & fees
26 Nov - 27 Nov
Simonton Court Historic Inn & Cottages
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Key West?
Forget the stress of everyday life and book yourself a lush spa hotel. Travelers love Key West for the sunsets and sea views so get ready to explore the great outdoors. Enjoy the live music and bars during your vacation. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key West?
Southernmost Beach Resort is a top beach spa hotel featuring 3 pools, a fitness center, a bar, and a restaurant. Treat yourself to a facial, couples treatments, or massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Key West include Pier House Resort & Spa and Casa Marina Key West, Curio Collection by Hilton.
How many spa hotels will I find in Key West?
Among Expedia’s 2802 accommodation options in Key West, there are 6 spa hotels.
What's there to see and do in Key West?
Take in the sights and attractions that Key West offers with a visit to Duval Street, Ernest Hemingway Home and Museum, and Key West Lighthouse and Keeper’s Quarters Museum. If you have a bit of extra time while you’re in the area, you might want to check out Harry S. Truman Little White House and Audubon House and Tropical Gardens.
What is a Key West spa hotel?
Spa hotels in Key West provide lodging and have an on-site spa which offers services such as couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.