Find Luxury Hotels in Key West, FL

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Key West Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Oceans Edge Key West Resort, Hotel & Marina

4.0 star property
8.8 out of 10, Excellent, (1530)
"Great place to stay "
The price is AED 1,055
AED 1,406 total
includes taxes & fees
8 Jan - 9 January 2025
Oceans Edge Key West Resort, Hotel & Marina

The Marker Key West Harbor Resort

4.0 star property
8.8 out of 10, Excellent, (1008)
"We like that The Marker is located in a quieter, more laid back part of town but centrally located for our favorite places. This was our 3rd stay! "
The price is AED 1,245
AED 1,623 total
includes taxes & fees
15 Jan - 16 January 2025
The Marker Key West Harbor Resort

Casa Marina Key West, Curio Collection by Hilton

4.0 star property
7.0 out of 10, Good, (1005)
"Amazing place for vacation! "
The price is AED 1,714
AED 2,160 total
includes taxes & fees
6 Jan - 7 January 2025
Casa Marina Key West, Curio Collection by Hilton

Southernmost Beach Resort

4.0 star property
8.6 out of 10, Excellent, (2202)
"Different types of accommodations, walking distance many things. Right on the beach. Activities daily at the resort. Super friendly staff, very welcoming!"
The price is AED 1,312
AED 1,723 total
includes taxes & fees
14 Jan - 15 January 2025
Southernmost Beach Resort

H2O Suites - Adults Only

3.5 star property
9.8 out of 10, Exceptional, (524)
"Incredible! Service, staff, amenities were all outstanding! We’ve stayed in 10 other places in Key West but this was by far the best. We’ll be back."
The price is AED 1,833
AED 2,227 total
includes taxes & fees
5 Jan - 6 January 2025
H2O Suites - Adults Only

Seashell Motel & Key West Hostel

1.5 star property
7.8 out of 10, Good, (1001)
"Nice peop’e"
The price is AED 562
AED 632 total
includes taxes & fees
5 Jan - 6 January 2025
Seashell Motel & Key West Hostel

The Mansion on the Sea - Southernmost House in the USA

3.0 star property
9.4 out of 10, Exceptional, (1000)
"The view is beautiful, gorgeous sunsets, the service is really friendly, clean rooms, and a great pool."
The price is AED 1,539
AED 1,844 total
includes taxes & fees
23 Dec - 24 Dec
The Mansion on the Sea - Southernmost House in the USA

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3.5 star property
8.2 out of 10, Very Good, (1010)
"Great pool bar , breakfast and convient shuttle "
The price is AED 1,054
AED 1,289 total
includes taxes & fees
7 Jan - 8 January 2025
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Santa Maria Suites

4.0 star property
9.6 out of 10, Exceptional, (1001)
"Our stay was perfect, great location, great pool, easy walking to restaurants and shops! "
The price is AED 1,815
AED 2,207 total
includes taxes & fees
13 Jan - 14 January 2025
Santa Maria Suites

Southwinds Motel

2.0 star property
8.8 out of 10, Excellent, (1046)
"This is an older, motel style property in a great location. It was clean and the staff were great but the rooms need updating which includes storage and ventilation. The room air was running all the time and left us sweaty and chilly at the same time due to the humidity in the room. There was not a bathroom fan which precluded anything drying. They remind you to reuse your towels but do not provide anywhere to actually hang them where they will dry between uses. We had the shower handle come...
The price is AED 1,030
AED 1,262 total
includes taxes & fees
23 Dec - 24 Dec
Southwinds Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Key West

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Key West?
Known for its ocean views and sunsets, Key West also has some interesting things to see and do including Duval Street, so you may want to take in the local sights during your visit.
What's the best luxury place to stay in Key West?
The Porch on Frances Inn is a luxury inn and popular for Expedia travelers looking for an elegant place to stay.
How many luxury hotels will I be able to find in Key West?
Lie in the lap of luxury during your getaway to Key West in one of Expedia’s 10 luxury hotels.
When can I expect good weather in Key West?
Planning for the weather is a good way to make your trip to Key West relaxing and enjoyable, especially when you’re splurging. The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 73°F. Average annual precipitation for Key West is 38 inches.
What's there to see and do in Key West?
Experience Key West with a stop at Duval Street, Ernest Hemingway Home and Museum, and Key West Lighthouse and Keeper’s Quarters Museum. If you have spare time during your trip, you might want to make a stop at Curry Mansion Museum and Harry S. Truman Little White House.