Find Luxury Hotels in Key West, FL

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Pick from 64 Key West Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Oceans Edge Key West Resort, Hotel & Marina
Pool
Oceans Edge Key West Resort, Hotel & Marina
4.0 star property
8.8 out of 10, Excellent, (1510)
"Great facility and staff."
The price is AED 632
AED 925 total
includes taxes & fees
3 Dec 2024 - 4 Dec 2024
Oceans Edge Key West Resort, Hotel & Marina
The Marker Key West Harbor Resort
Exterior
The Marker Key West Harbor Resort
4.0 star property
8.8 out of 10, Excellent, (1001)
"It was very clean, close to everything we needed! Would stay again! "
The price is AED 888
AED 1,205 total
includes taxes & fees
1 Dec 2024 - 2 Dec 2024
The Marker Key West Harbor Resort
Casa Marina Key West, Curio Collection by Hilton
Exterior
Casa Marina Key West, Curio Collection by Hilton
5.0 star property
7.0 out of 10, Good, (1016)
"A Great and lovely service "
The price is AED 1,124
AED 1,468 total
includes taxes & fees
5 Nov 2024 - 6 Nov 2024
Casa Marina Key West, Curio Collection by Hilton
Southernmost Beach Resort
Exterior
Southernmost Beach Resort
4.0 star property
8.6 out of 10, Excellent, (2173)
"The oversized showers "
The price is AED 865
AED 1,204 total
includes taxes & fees
1 Dec 2024 - 2 Dec 2024
Southernmost Beach Resort
H2O Suites - Adults Only
Room
H2O Suites - Adults Only
3.5 star property
9.8 out of 10, Exceptional, (518)
"WOW I thought I would love this property but the staff was just not the best. Now not everyone but some just were not kind and some could not help us out with simple questions "
The price is AED 1,282
AED 1,579 total
includes taxes & fees
4 Nov 2024 - 5 Nov 2024
H2O Suites - Adults Only
Seashell Motel & Key West Hostel
Exterior
Seashell Motel & Key West Hostel
1.5 star property
7.8 out of 10, Good, (1001)
"X"
The price is AED 360
AED 405 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Seashell Motel & Key West Hostel
The Mansion on the Sea - Southernmost House in the USA
Front of property
The Mansion on the Sea - Southernmost House in the USA
3.0 star property
9.2 out of 10, Wonderful, (1007)
"Staff is fantastic, breakfast is delicious, location cannot be beat!!! The cottages have a gorgeous view of the ocean and the sunrise! Will definitely recommend and stay here again! "
The price is AED 1,833
AED 2,134 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
The Mansion on the Sea - Southernmost House in the USA
Fairfield Inn & Suites by Marriott Key West at the Keys Collection
Pool
Fairfield Inn & Suites by Marriott Key West at the Keys Collection
3.5 star property
8.2 out of 10, Very Good, (1010)
"Good place for the price. Far from most things so the free shuttle to Old Town was very useful. Not a perfect score since the wifi never worked for us and we were doing a work-cation for some of our trip. Were told by the front desk that they were aware of the issue, "the wifi works on phones but not laptops" and we were welcome to come use the lobby wifi. No plans to fix it either apparently. Cell signal was also limited so hotspotting was less than ideal. "
The price is AED 558
AED 721 total
includes taxes & fees
20 Nov 2024 - 21 Nov 2024
Fairfield Inn & Suites by Marriott Key West at the Keys Collection
Santa Maria Suites
Room
Santa Maria Suites
4.0 star property
9.6 out of 10, Exceptional, (1005)
"The absolute best!"
The price is AED 1,319
AED 1,619 total
includes taxes & fees
5 Nov 2024 - 6 Nov 2024
Santa Maria Suites
Southwinds Motel
Front of property
Southwinds Motel
2.0 star property
8.8 out of 10, Excellent, (1017)
"Will definitely be back - a small jem right by Duval St and the Southernmost Point!! "
The price is AED 673
AED 846 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Southwinds Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Key West?
Known for its ocean views and sunsets, Key West also has some interesting things to see and do including Duval Street and Mallory Square, so you may want to take in the local sights during your visit.
What's the best luxury place to stay in Key West?
Casa Marina Key West, Curio Collection by Hilton is a luxury resort with a private beach and a full-service spa, and it’s a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale option for your vacation is The Porch on Frances Inn.
How many luxury hotels will I be able to find in Key West?
Lie in the lap of luxury during your getaway to Key West in one of Expedia’s 10 luxury hotels.
When can I expect good weather in Key West?
Planning for the weather is a good way to make your trip to Key West relaxing and enjoyable, especially when you’re splurging. The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 73°F. Average annual precipitation for Key West is 38 inches.
What's there to see and do in Key West?
Experience Key West with a stop at Duval Street, Mallory Square, and Ernest Hemingway Home and Museum. If you have spare time during your trip, you might want to make a stop at Key West Lighthouse and Keeper’s Quarters Museum and Curry Mansion Museum.