Find Luxury Hotels in Key West, FL

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Pick from 64 Key West Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Oceans Edge Key West Resort, Hotel & Marina
Pool
Oceans Edge Key West Resort, Hotel & Marina
4.0 star property
8.8 out of 10, Excellent, (1499)
"I thoroughly enjoyed my stay at oceans edge. I like how it is quaint and relaxing. On the other hand, the shuttle makes it easy to go downtown where all the business is happening. When i return to Key West i plan to stay with Oceans Edge."
The price is AED 659
AED 955 total
includes taxes & fees
1 Dec - 2 Dec
Oceans Edge Key West Resort, Hotel & Marina
The Marker Key West Harbor Resort
Exterior
The Marker Key West Harbor Resort
4.0 star property
8.8 out of 10, Excellent, (1001)
"Location was outstanding and staff was exceptional. "
The price is AED 919
AED 1,257 total
includes taxes & fees
1 Dec - 2 Dec
The Marker Key West Harbor Resort
Casa Marina Key West, Curio Collection by Hilton
Exterior
Casa Marina Key West, Curio Collection by Hilton
4.0 star property
7.0 out of 10, Good, (1004)
"Absolutely loved this place. Historic, newly renovated, close enough to tourist attractions without being right in the action. My only regret was not staying another day or two to enjoy the private beach! Very large room, beautiful bathroom with wonderful rainfall showerhead. "
The price is AED 1,086
AED 1,433 total
includes taxes & fees
3 Dec - 4 Dec
Casa Marina Key West, Curio Collection by Hilton
Southernmost Beach Resort
Exterior
Southernmost Beach Resort
4.0 star property
8.6 out of 10, Excellent, (2181)
"I loved this place. They tried to do anything we asked and smiled about it. We will be back."
The price is AED 893
AED 1,235 total
includes taxes & fees
17 Dec - 18 Dec
Southernmost Beach Resort
H2O Suites - Adults Only
Room
H2O Suites - Adults Only
3.5 star property
9.8 out of 10, Exceptional, (521)
"Lovely rooms and courtyard, and the pool bar is intimate and pleasant with complimentary mimosas etc all day. The staff is friendly and knowledgeable. We would definitely stay again."
The price is AED 1,319
AED 1,619 total
includes taxes & fees
19 Dec - 20 Dec
H2O Suites - Adults Only
Seashell Motel & Key West Hostel
Exterior
Seashell Motel & Key West Hostel
1.5 star property
7.8 out of 10, Good, (1000)
"Good location"
The price is AED 440
AED 495 total
includes taxes & fees
24 Nov - 25 Nov
Seashell Motel & Key West Hostel
The Mansion on the Sea - Southernmost House in the USA
Front of property
The Mansion on the Sea - Southernmost House in the USA
3.0 star property
9.4 out of 10, Exceptional, (1001)
"It is a well maintained historical home with beauty and charm"
The price is AED 1,649
AED 1,931 total
includes taxes & fees
24 Nov - 25 Nov
The Mansion on the Sea - Southernmost House in the USA
Fairfield Inn & Suites by Marriott Key West at the Keys Collection
Pool
Fairfield Inn & Suites by Marriott Key West at the Keys Collection
3.5 star property
8.2 out of 10, Very Good, (1003)
"Good place to stay "
The price is AED 547
AED 709 total
includes taxes & fees
4 Dec - 5 Dec
Fairfield Inn & Suites by Marriott Key West at the Keys Collection
Santa Maria Suites
Room
Santa Maria Suites
4.0 star property
9.6 out of 10, Exceptional, (1000)
"Our room was perfect! The entire property is super clean. Upon arrival, we were greeted by the very nice Matilda, the front desk receptionist. She was very friendly, and was able to accommodate our early check-in! Once she got us quickly checked in, we told her after driving all day, we were starving. She recommended a great place down the street to eat with lobster pizza. Great recommendation, as it was delicious. After the good meal, we enjoyed happy hour at the pool with Wilfredo serving us...
The price is AED 1,392
AED 1,688 total
includes taxes & fees
2 Dec - 3 Dec
Santa Maria Suites
Southwinds Motel
Front of property
Southwinds Motel
2.0 star property
8.8 out of 10, Excellent, (1016)
"Cute room close to Duval Street. Would stay again"
The price is AED 602
AED 762 total
includes taxes & fees
3 Dec - 4 Dec
Southwinds Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Key West?
Known for its ocean views and sunsets, Key West also has some interesting things to see and do including Duval Street, so you may want to take in the local sights during your visit.
What's the best luxury place to stay in Key West?
The Porch on Frances Inn is a luxury inn and popular for Expedia travelers looking for an elegant place to stay.
How many luxury hotels will I be able to find in Key West?
Lie in the lap of luxury during your getaway to Key West in one of Expedia’s 10 luxury hotels.
When can I expect good weather in Key West?
Planning for the weather is a good way to make your trip to Key West relaxing and enjoyable, especially when you’re splurging. The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 73°F. Average annual precipitation for Key West is 38 inches.
What's there to see and do in Key West?
Experience Key West with a stop at Duval Street, Ernest Hemingway Home and Museum, and Key West Lighthouse and Keeper’s Quarters Museum. If you have spare time during your trip, you might want to make a stop at Harry S. Truman Little White House and Audubon House and Tropical Gardens.