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Find Family Hotels in Cape Girardeau, MO

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Pick from 10 Cape Girardeau Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1001)
"We stayed here about six-months ago and enjoyed it so well, we booked it again. It is a great value for the money. The breakfast is very good!"
The price is AED 360
AED 402 total
includes taxes & fees
6 Nov - 7 Nov
Auburn Place Hotel And Suites
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (811)
"Wonderful"
The price is AED 364
AED 410 total
includes taxes & fees
10 Nov - 11 Nov
Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (1003)
"Clean beds and lobby was nice. "
The price is AED 349
AED 387 total
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1003)
"I cannot say enough things about the entire staff. Everyone from the front desk personnel to the breakfast attendants to housekeeping were so friendly, efficient, and obviously happy in their jobs. Drury Inn should be very proud."
The price is AED 218
AED 246 total
includes taxes & fees
10 Nov - 11 Nov
Pear Tree Inn Cape Girardeau Near the Medical Center
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, (671)
"Room well kept; beds comfortable, and breakfast was delicious. We love the cookies each night. "
The price is AED 403
AED 447 total
includes taxes & fees
17 Nov - 18 Nov
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1000)
"We had excellent stays at this hotel. The staff is friendly and the hotel is very clean. "
The price is AED 235
AED 265 total
includes taxes & fees
10 Nov - 11 Nov
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (693)
"Definitely loud on the freeway side, and the bedroom doesn’t get very cool with the wall fan replacing an AC in there, but, the people are great. Everything is clean, parking is great. The outdoor grill is an awesome extra. The gym could use a bench and maybe a cable machine or something? I’d definitely appreciate more gym options. That said, I always stay here when I come to town because it’s nice andI love having the kitchen. "
The price is AED 301
AED 360 total
includes taxes & fees
24 Nov - 25 Nov
Candlewood Suites Cape Girardeau, an IHG Hotel
Quality Inn
2.5 star property
7.0 out of 10, Good, (513)
"We really enjoyed our 2 day stay there. Staff nice, rooms clean, parking was easy. My only complaint was breakfast. There could/should have had a better selection. Overall....a great stay. "
The price is AED 224
AED 253 total
includes taxes & fees
6 Nov - 7 Nov
Quality Inn
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1003)
"The evening food & drinks was great! The breakfast was good too!"
The price is AED 364
AED 410 total
includes taxes & fees
10 Nov - 11 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Cape Girardeau like for family-friendly vacations?
You might want to consider the historic destination of Cape Girardeau if you’ve been thinking about a trip for the whole family. The restaurants here makes this an attractive vacation spot for families. Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is the closest airport, or Cairo, IL (CIR-Cairo Regional), which is located 23.4 mi (37.6 km) from the city center.
How many family-friendly hotels are there in Cape Girardeau?
Expedia has 12 family-friendly hotels and other accommodations in Cape Girardeau.
When's the best time to book a family-friendly vacation in Cape Girardeau?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What's there to see and do with your family in Cape Girardeau?
While you and your family are visiting Cape Girardeau, you might want to check out some kid-friendly attractions such as Show Me Center, Cape Splash Family Aquatic Center, and Trail of Tears State Park. Make sure you have lots of time for activities like Shawnee National Forest and Cape Girardeau Conservation Nature Center.