Photo by Skyy

Find Family Hotels in Cape Girardeau, MO

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Cape Girardeau Family Hotels

This weekend
Next weekend

Compare Cape Girardeau Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (927)
"Always The best hotel "
The price is AED 347
AED 392 total
includes taxes & fees
1 Jun - 2 Jun
Drury Inn & Suites Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Will definitely stay there again!!"
The price is AED 364
AED 410 total
includes taxes & fees
18 May - 19 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Continental breakfast where the hostess made the waffles for you; friendly staff."
The price is AED 215
AED 242 total
includes taxes & fees
11 May - 12 May
Pear Tree Inn Cape Girardeau Near the Medical Center

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

10.0 out of 10, Exceptional, (214)
"Clean and large space. Easy access to lots of shops and restaurants. Great hosts."
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (707)
"Great location"
The price is AED 403
AED 454 total
includes taxes & fees
18 May - 19 May
Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"Nice place, would stay here again "
The price is AED 264
AED 298 total
includes taxes & fees
11 May - 12 May
Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (779)
"Was clean and comfortable "
The price is AED 286
AED 343 total
includes taxes & fees
1 Jun - 2 Jun
Candlewood Suites Cape Girardeau by IHG

Quality Inn

2.5 star property
7.0 out of 10, Good, (572)
"Love it very clean and very quiet love the experience"
The price is AED 245
AED 276 total
includes taxes & fees
13 May - 14 May
Quality Inn

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great stay!!"
The price is AED 331
AED 373 total
includes taxes & fees
11 May - 12 May
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Cape Girardeau

Frequently asked questions

What's Cape Girardeau like for family-friendly vacations?
You might want to consider the historic destination of Cape Girardeau if you’ve been thinking about a trip for the whole family. The restaurants here makes this an attractive vacation spot for families. Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is the closest airport, or Cairo, IL (CIR-Cairo Regional), which is located 23.4 mi (37.6 km) from the city center.
What's the best accommodation for a family vacation to Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it’s a top choice on Expedia for families. Other good options for your family trip include Pear Tree Inn Cape Girardeau Near the Medical Center and Pear Tree Inn Cape Girardeau West.
How many family-friendly hotels are there in Cape Girardeau?
Expedia has 12 family-friendly hotels and other accommodations in Cape Girardeau.
When's the best time to book a family-friendly vacation in Cape Girardeau?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What's there to see and do with your family in Cape Girardeau?
While you and your family are visiting Cape Girardeau, you might want to check out some kid-friendly attractions such as Show Me Center, Cape Splash Family Aquatic Center, and Shawnee National Forest. Make sure you have lots of time for activities like Cape Girardeau Conservation Nature Center and Lazy L Safari Park.