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Find Family Hotels in Cape Girardeau, MO

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Compare Cape Girardeau Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites Cape Girardeau
Exterior

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (845)
"The staff was super friendly. Really good!"
The price is AED 331
AED 373 total
includes taxes & fees
28 Dec - 29 Dec
Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (1001)
"I stayed over with 6 of my volleyball players for a tournament. Staff was friendly and helpful. Room was clean. "
The price is AED 364
AED 410 total
includes taxes & fees
12 Jan - 13 January 2025
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"clean room. barking dog"
The price is AED 239
AED 269 total
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Hampton Inn Cape Girardeau I 55 East
Pool

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (683)
"Always a nice stay"
The price is AED 403
AED 454 total
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West
Exterior

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Always a great place to stay. "
The price is AED 231
AED 261 total
includes taxes & fees
26 Dec - 27 Dec
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 star property
8.2 out of 10, Very Good, (708)
"Very spacious room with very comfortable bed."
The price is AED 242
AED 294 total
includes taxes & fees
5 Jan - 6 January 2025
Candlewood Suites Cape Girardeau, an IHG Hotel
Quality Inn
Exterior

Quality Inn

2.5 star property
7.0 out of 10, Good, (523)
"It was quite and clean"
The price is AED 224
AED 253 total
includes taxes & fees
23 Dec - 24 Dec
Quality Inn
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Really good. My kiddo had a tonsillectomy done at the hospital there and the staff were very helpful. Got us extra yogurts so she could eat etc…. Thank you! "
The price is AED 364
AED 410 total
includes taxes & fees
27 Dec - 28 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Cape Girardeau like for family-friendly vacations?
You might want to consider the historic destination of Cape Girardeau if you’ve been thinking about a trip for the whole family. The restaurants here makes this an attractive vacation spot for families. Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is the closest airport, or Cairo, IL (CIR-Cairo Regional), which is located 23.4 mi (37.6 km) from the city center.
What's the best accommodation for a family vacation to Cape Girardeau?
Pear Tree Inn Cape Girardeau West is a hotel with free parking and free continental breakfast, and it’s a top choice on Expedia for families. Other good options for your family trip include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau Near the Medical Center.
How many family-friendly hotels are there in Cape Girardeau?
Expedia has 12 family-friendly hotels and other accommodations in Cape Girardeau.
When's the best time to book a family-friendly vacation in Cape Girardeau?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What's there to see and do with your family in Cape Girardeau?
While you and your family are visiting Cape Girardeau, you might want to check out some kid-friendly attractions such as Show Me Center, Trail of Tears State Park, and Shawnee National Forest. Make sure you have lots of time for activities like Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center.