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Find Business Hotels in Cape Girardeau, MO

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Check availability on Cape Girardeau Business Hotels

Compare Cape Girardeau Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Will definitely stay there again!!"
The price is AED 378
AED 427 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (917)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, all was good. Oh yeah the dinner & breakfast was great the place was clean and our room was fantastic. Value was excellent. Allen B."
The price is AED 347
AED 392 total
includes taxes & fees
18 Apr - 19 Apr
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Nicr"
The price is AED 264
AED 298 total
includes taxes & fees
17 Apr - 18 Apr
Pear Tree Inn Cape Girardeau West
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (563)
"It was okay"
The price is AED 246
AED 278 total
includes taxes & fees
14 Apr - 15 Apr
Quality Inn
Candlewood Suites Cape Girardeau by IHG
Exterior

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (765)
"Very nice place to stay and friendly people"
The price is AED 301
AED 360 total
includes taxes & fees
20 Apr - 21 Apr
Candlewood Suites Cape Girardeau by IHG
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1005)
"We stay here several times a year and it’s always a wonderful time. All of the staff go above and beyond and we are always very comfortable "
The price is AED 347
AED 392 total
includes taxes & fees
17 Apr - 18 Apr
Drury Plaza Hotel Cape Girardeau Conference Center
Hampton Inn Cape Girardeau I 55 East
Reception

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (701)
"Great experience "
The price is AED 403
AED 454 total
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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