Photo by Skyy
Find 3 Star Hotels in Cape Girardeau, MO from AED 331
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Cape Girardeau 3 Star Hotels
Compare Cape Girardeau 3 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Riverview
The Riverview
9.2 out of 10, Wonderful, (191)
The price is AED 345
AED 390 total
includes taxes & fees
23 Mar - 24 Mar

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1006)
The price is AED 347
AED 392 total
includes taxes & fees
30 Mar - 31 Mar

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
9.6 out of 10, Exceptional, (403)
The price is AED 492
AED 558 total
includes taxes & fees
6 Apr - 7 Apr

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (910)
The price is AED 347
AED 392 total
includes taxes & fees
30 Mar - 31 Mar

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (1003)
The price is AED 331
AED 349 total
includes taxes & fees
27 Mar - 28 Mar

EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
9.6 out of 10, Exceptional, (68)
The price is AED 429
AED 467 total
includes taxes & fees
23 Mar - 24 Mar

Makanda Inn
Makanda Inn
10.0 out of 10, Exceptional, (29)

Cozy Anna Home Near Southern Illinois Attractions!
Cozy Anna Home Near Southern Illinois Attractions!
10.0 out of 10, Exceptional, (1)
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Cape Girardeau.

Davie School Inn
300 Freeman St, Anna, IL
The price is AED 617 per night from Mar 23 to Mar 24
AED 617
AED 684 total
includes taxes & fees
23 Mar - 24 Mar
10/10 Exceptional! (47 reviews)
Still don't see what you're looking for?
See all properties in Cape Girardeau.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Cape Girardeau
Trip time! Discover the riverfront, history, and university life in Cape Girardeau.

Photo by Skyy
Open Photo by Skyy
Recent reviews of Cape Girardeau hotels
Recent reviews of Cape Girardeau hotels

Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"lots of room and very clean. The rooms were great and the evening meal and breakfast were great."
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 4 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Cape Girardeau Hotels by Star Rating
Stay near popular Cape Girardeau attractions
- Hotels near Southeast Missouri State University
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Cape Rock Park
- Hotels near Hunter Valley Winery
- Hotels near Riverfront Park
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Fort D Historic Site
- Hotels near Lazy L Safari Park
- Hotels near eDen Spa & Salon
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Giant City State Park
- Hotels near Trail of Tears State Park
- Hotels near Stone Creek Golf Club and Resort
- Hotels near StarView Vineyards
- Hotels near Bollinger Mill State Historic Site
- Hotels near Pomona Winery
More Hotel Options in Cape Girardeau
- Adults Only Resorts & Hotels in Cape Girardeau
- Adventure Hotels in Cape Girardeau
- Business Hotels in Cape Girardeau
- Casinos in Cape Girardeau
- Cheap Hotels in Cape Girardeau
- Family Hotels in Cape Girardeau
- Historic Hotels in Cape Girardeau
- Hotel Wedding Venues in Cape Girardeau
- Hotels with Bars in Cape Girardeau
- Hotels with Free Parking in Cape Girardeau
- Hotels with Hot Tubs in Cape Girardeau
- Hotels with WiFi in Cape Girardeau
- Hotels with a Pool in Cape Girardeau
- Hotels with an Indoor Pool in Cape Girardeau
- Hotels with smoking rooms in Cape Girardeau
- Luxury Hotels in Cape Girardeau
- Pet-friendly Hotels in Cape Girardeau
- Resorts & Hotels with Spas in Cape Girardeau
- Romantic Hotels in Cape Girardeau
- Shopping Hotels in Cape Girardeau
- Winery Hotels in Cape Girardeau
More Accommodation Types in Cape Girardeau
Explore more hotels
- Town House Inn Cape Giradreau
- Hampton Inn Cape Girardeau I 55 East
- Serenity South -- Gardens, River-Views, and Refreshing Space
- Tru By Hilton Cape Girardeau
- 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
- Rockwood Inn
- The Twisted Sassafras Treehouse
- Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
- 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
- Charming Secluded Getaway Cabin within minutes of amenities
- "Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
- Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
- Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
- Historical 'Kage House' Short Term Rental located in "Old Town Cape"
- Loft Apartment Across From Semo University Houch Field House. Walk To Events
- River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi
- Little Blue Cottage on Spanish
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Drury Inn & Suites Jackson MO
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.