Find hotels near Isle Casino Cape Girardeau, Cape Girardeau from AED 231
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Compare 224 hotels close to Isle Casino Cape Girardeau with room rates, reviews, and availability. Most hotels are fully refundable.

Rockwood Inn
Rockwood Inn
9.8 out of 10, Exceptional, (6)
The price is AED 552
AED 623 total
includes taxes & fees
20 Apr - 21 Apr

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
9.6 out of 10, Exceptional, (406)
The price is AED 459
AED 520 total
includes taxes & fees
27 Apr - 28 Apr

The Riverview
The Riverview
9.2 out of 10, Wonderful, (213)
The price is AED 321
AED 362 total
includes taxes & fees
20 Apr - 21 Apr

Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
6.0 out of 10, (178)
The price is AED 231
AED 270 total
includes taxes & fees
7 Apr - 8 Apr

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (699)
The price is AED 403
AED 454 total
includes taxes & fees
13 Apr - 14 Apr

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1005)
The price is AED 347
AED 392 total
includes taxes & fees
13 Apr - 14 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels near Other Cape Girardeau Attractions
Hotels near Other Cape Girardeau Attractions
Southeast Missouri State University
4.5/5(76 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Recent reviews of Isle Casino Cape Girardeau hotels
Recent reviews of Isle Casino Cape Girardeau hotels

Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
Great roadtrip hotel
"It was a great hotel and the staff were very helpful to us with our kids at breakfast time. The kids loved getting popcorn from the staff after a long day of driving."
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 2 days ago
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Hotels near popular Cape Girardeau Attractions
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Southeast Missouri State University
- Hotels near Hunter Valley Winery
- Hotels near Riverfront Bridge Park
- Hotels near Trail of Tears State Park
- Hotels near Riverfront Park
- Hotels near Cape Rock Park
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Cape Splash Family Aquatic Center
- Hotels near eDen Spa & Salon
- Hotels near Fort D Historic Site
- Hotels near Lazy L Safari Park
- Hotels near Steele Crest Winery
- Hotels near Litz Park
Other Hotels near Isle Casino Cape Girardeau, Cape Girardeau
More Hotel Options in Isle Casino Cape Girardeau
- Adventure Hotels
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- Hotel Wedding Venues
- Hotels with Bars
- Hotels with Free Parking
- Hotels with Hot Tubs
- Hotels with WiFi
- Hotels with a Pool
- Hotels with an Indoor Pool
- Hotels with smoking rooms
- Luxury Hotels
- Pet-friendly Hotels
- Resorts & Hotels with Spas
- Shopping Hotels
- Winery Hotels
Explore more hotels
- Candlewood Suites Cape Girardeau by IHG
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Hampton Inn Cape Girardeau I 55 East
- Quality Inn
- 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Tru By Hilton Cape Girardeau
- Comfort Suites Jackson-Cape Girardeau
- The Twisted Sassafras Treehouse
- Charming Secluded Getaway Cabin within minutes of amenities
- Town House Inn