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Find Resorts & Hotels with Spas in Cape Girardeau, MO

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Check availability on Cape Girardeau Resorts & Hotels with Spas

Compare Cape Girardeau Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (692)
"family trip to Cape G. This Hampton Inn is right off I-55 and also right off the roads to downtown Cape G. Plenty of places to eat and walk the dogs"
The price is AED 403
AED 454 total
includes taxes & fees
30 Mar - 31 Mar
Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Nice place and affordable. The breakfast is pretty simple. "
The price is AED 248
AED 280 total
includes taxes & fees
24 Mar - 25 Mar
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (908)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."
The price is AED 347
AED 391 total
includes taxes & fees
30 Mar - 31 Mar
Drury Inn & Suites Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Great stay. Love the atmosphere and food. Our stay was for basketball tournament. Enjoyed every bit of the stay."
The price is AED 347
AED 391 total
includes taxes & fees
30 Mar - 31 Mar
Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Love everything "
The price is AED 364
AED 410 total
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (741)
"Every thing was handled quickly. The room was awesome. The shower was great. I would say the only drawback was the refrigerator and freezer were not on and I did not realize that. I was on at my previous stay earlier in the week and some ice cream I put in the freezer melted."
The price is AED 286
AED 343 total
includes taxes & fees
30 Mar - 31 Mar
Candlewood Suites Cape Girardeau by IHG

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"The beds and linens were wonderful and the room smelled so fresh. Great stay and at a affordable price. Highly recommend it."
The price is AED 248
AED 280 total
includes taxes & fees
17 Mar - 18 Mar
Pear Tree Inn Cape Girardeau Near the Medical Center

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (172)
"This is a unique place, having a kitchen and clean and spacious rooms, very comfortable "
The price is AED 220
AED 257 total
includes taxes & fees
16 Mar - 17 Mar
Town House Inn Cape Giradreau

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (27)
"Amazing property that we simply didn't stay long enough to enjoy in its completeness. Billiards and Putt-Putt on entry, so attractive that we started playing before we even unpacked! I'm very artsy interior, and lots of room and outdoor fire pit, multiple decks, and an in-ground pool. The home is even on the grounds, an event venue. Probably a wonderful combination for them! Would enjoy returning, but for a longer stay will you could enjoy all with the property had to offer! Highly recommend it"
The price is AED 551
AED 862 total
includes taxes & fees
16 Mar - 17 Mar
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (128)
"We had a wonderful time at Serenity South! The house is quiet and very clean, in walking distance of fantastic shops and fun places to eat. We look forward to returning next year!"
The price is AED 551
AED 900 total
includes taxes & fees
16 Mar - 17 Mar
Serenity South -- Gardens, River-Views, and Refreshing Space
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Cape Girardeau?
Treat yourself to some pampering and book a hotel with a spa. Travelers recommend the gourmet restaurants in Cape Girardeau. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness center.
How many spa hotels will I find in Cape Girardeau?
Among Expedia’s 56 accommodation options in Cape Girardeau, there is 1 spa hotel.
What's there to see and do in Cape Girardeau?
Experience all that Cape Girardeau has to offer when you visit Isle Casino Cape Girardeau, Show Me Center, and Hunter Valley Winery. If you have a bit of extra time while you’re in the area, you might want to check out Trail of Tears State Park and Shawnee National Forest.
What is a Cape Girardeau spa hotel?
Spa hotels in Cape Girardeau have full on-site spas offering services such as massages and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.