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Compare 171 Vacation Homes in Southeast Missouri with updated reviews, rates, and availability.

Serenity South -- Gardens, River-Views, and Refreshing Space
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (128)
The price is AED 551
AED 900 total
includes taxes & fees
31 Mar - 1 Apr

The Sutton House 2 blocks from Main Street & Courthouse Square
The Sutton House 2 blocks from Main Street & Courthouse Square
10.0 out of 10, Exceptional, (20)
The price is AED 500
AED 648 total
includes taxes & fees
2 Apr - 3 Apr

"Little Brick House on Main (1865)”
"Little Brick House on Main (1865)”
10.0 out of 10, Exceptional, (39)
The price is AED 485
AED 632 total
includes taxes & fees
2 Apr - 3 Apr

Cozy Three bedroom home in Central Farmington
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (18)
The price is AED 441
AED 961 total
includes taxes & fees
31 Mar - 1 Apr

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
8.8 out of 10, Excellent, (27)
The price is AED 551
AED 858 total
includes taxes & fees
7 Apr - 8 Apr

Shawnee Creek Hideaway - Close to Eminence and the Jacks Fork River!
Shawnee Creek Hideaway - Close to Eminence and the Jacks Fork River!
10.0 out of 10, Exceptional, (60)

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
The price is AED 1,098
AED 1,738 total
includes taxes & fees
7 Apr - 8 Apr

Wren’s Hideaway Sleeps 8 Historic downtown neighborhood Charming & Relaxing
Wren’s Hideaway Sleeps 8 Historic downtown neighborhood Charming & Relaxing
10.0 out of 10, Exceptional, (18)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Southeast Missouri

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
9.4 out of 10, Exceptional, (139)
The price is AED 584
AED 673 total
includes taxes & fees
16 Apr - 17 Apr

Postcard Cabins St. Francois
Postcard Cabins St. Francois
10.0 out of 10, Exceptional, (3)
The price is AED 331
AED 356 total
includes taxes & fees
13 Apr - 14 Apr

River front property HOT TUB, Kayak, tubing, and fishing
River front property HOT TUB, Kayak, tubing, and fishing
9.6 out of 10, Exceptional, (83)
The price is AED 621
AED 1,000 total
includes taxes & fees
30 Mar - 31 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Southeast Missouri hotels
Recent reviews of Southeast Missouri hotels

Pear Tree Inn Sikeston
5/5 Excellent
"well lighted parking"
A verified traveler stayed at Pear Tree Inn Sikeston
Posted 19 hours ago
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