Find Business Hotels in Southeast Missouri, MO

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Check availability on Southeast Missouri Business Hotels

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Compare Southeast Missouri Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Clean, friendly and affordable. We would definitely stay here again!"
The price is AED 314
AED 361 total
includes taxes & fees
13 Apr - 14 Apr
Pear Tree Inn Sikeston

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"We enjoyed our stay both times on our vacation to New Orleans."
The price is AED 378
AED 427 total
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1004)
"In addition to being clean and very quiet, they offered a wide selection of breakfast foods. We would definitely stay here again."
The price is AED 331
AED 349 total
includes taxes & fees
10 Apr - 11 Apr
Drury Inn & Suites Jackson MO

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1004)
"The gentleman at the front desk was super nice , friendly and just fun when we checked in , we had a quick overnight stay in town ! Pool was clean nice and warm , the next morning breakfast was nice clean and stocked and the young lady cleaning and keeping it full was very friendly also , plus we were able to have are Yorkie in room at a reasonable charge "
The price is AED 315
AED 359 total
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus Sikeston

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (916)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, all was good. Oh yeah the dinner & breakfast was great the place was clean and our room was fantastic. Value was excellent. Allen B."
The price is AED 347
AED 392 total
includes taxes & fees
27 Apr - 28 Apr
Drury Inn & Suites Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
8.8 out of 10, Excellent, (558)
"We skipped the breakfast - all cold and unappealing."
The price is AED 294
AED 328 total
includes taxes & fees
27 Apr - 28 Apr
Microtel Inn & Suites by Wyndham Sainte Genevieve

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1007)
"I"
The price is AED 264
AED 298 total
includes taxes & fees
5 May - 6 May
Pear Tree Inn Cape Girardeau West

Quality Inn Festus

3.0 star property
6.8 out of 10, (894)
"Room and bathroom were clean, our room’s carpet had holes and was ripped up by the AC the room smelled moldy. Employees were polite"
The price is AED 282
AED 322 total
includes taxes & fees
19 Apr - 20 Apr
Quality Inn Festus

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (906)
"Great stay."
The price is AED 197
AED 224 total
includes taxes & fees
13 Apr - 14 Apr
Baymont Inn and Suites by Wyndham Farmington, MO

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"Everything was good for a guick one night stay. Nothing fancy but there were 5 of us and plenty of room. Breakfast not great but just enough choices for 3 adults and 2 kids. Only problem was pull out sofa bed was broken but it was big enough to just sleep on top. For the price it was good. I would recommend. "
The price is AED 281
AED 320 total
includes taxes & fees
9 Apr - 10 Apr
Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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