Find 2 Star Hotels in Southeast Missouri, MO
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Compare Southeast Missouri 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
8.0 out of 10, Very Good, (906)
The price is AED 194
AED 221 total
includes taxes & fees
27 Apr - 28 Apr

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
8.0 out of 10, Very Good, (1001)
The price is AED 290
AED 306 total
includes taxes & fees
12 Apr - 13 Apr

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1001)
The price is AED 297
AED 338 total
includes taxes & fees
13 Apr - 14 Apr

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1002)
The price is AED 378
AED 427 total
includes taxes & fees
4 May - 5 May

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
9.0 out of 10, Wonderful, (529)
The price is AED 303
AED 328 total
includes taxes & fees
10 Apr - 11 Apr

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff
9.4 out of 10, Exceptional, (710)
The price is AED 342
AED 386 total
includes taxes & fees
13 Apr - 14 Apr

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1003)
The price is AED 314
AED 361 total
includes taxes & fees
14 Apr - 15 Apr

The Farmstead Hotel
The Farmstead Hotel
8.8 out of 10, Excellent, (324)
The price is AED 324
AED 368 total
includes taxes & fees
10 Apr - 11 Apr
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Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Recent reviews of Southeast Missouri hotels
Recent reviews of Southeast Missouri hotels

Super 8 by Wyndham Perryville
5/5 Excellent
"The staff was very friendly and the guy at the front desk was helpful with ever thing we asked about hotel was nice clean and quiet. Thus was my second time staying at this same hotel"
A verified traveler stayed at Super 8 by Wyndham Perryville
Posted 9 days ago

Motel 6 Poplar Bluff, MO
5/5 Excellent
"."
A verified traveler from Clinton stayed at Motel 6 Poplar Bluff, MO
Posted 9 days ago
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Southeast Missouri Hotels by Star Rating
Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Hotels near Elephant Rocks State Park
- Hotels near Johnson's Shut-ins State Park
- Hotels near Southeast Missouri State University
- Hotels near Ozark National Scenic Riverways
- Hotels near Echo Bluff State Park
- Hotels near Lake Wappapello
- Hotels near Isle Casino Cape Girardeau
- Hotels near Alley Spring & Mill
- Hotels near Big Spring
- Hotels near Century Casino Caruthersville
- Hotels near Bonne Terre Mine
- Hotels near Current River State Park
- Hotels near Taum Sauk Mountain State Park
- Hotels near Sainte Genevieve Winery
- Hotels near Hunter Valley Winery
- Hotels near Rocky Falls
- Hotels near K Bridge Recreation Area
- Hotels near Crown Valley Winery
- Hotels near Black River Coliseum
- Hotels near National Shrine of Our Lady of the Miraculous Medal
More Hotel Options in Southeast Missouri
- Adults Only Resorts & Hotels in Southeast Missouri
- Adventure Hotels in Southeast Missouri
- Business Hotels in Southeast Missouri
- Casinos in Southeast Missouri
- Cheap Hotels in Southeast Missouri
- Family Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Historic Hotels in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Hotel with a Concierge in Southeast Missouri
- Hotels with Bars in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Waterslides in Southeast Missouri
- Hotels with WiFi in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Resorts & Hotels with Spas in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Shopping Hotels in Southeast Missouri
- Ski Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
More Accommodation Types in Southeast Missouri
- Vacation Homes in Southeast Missouri
- Cabin Rentals in Southeast Missouri
- Cottages in Southeast Missouri
- Apartments in Southeast Missouri
- Motels in Southeast Missouri
- Farmstay in Southeast Missouri
- RV Parks in Southeast Missouri
- Condo Rentals in Southeast Missouri
- Lodges in Southeast Missouri
- Aparthotels in Southeast Missouri
- B&B in Southeast Missouri
- Villas in Southeast Missouri
Explore more hotels
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Drury Inn & Suites Cape Girardeau
- Best Western Plus Sikeston
- Drury Inn & Suites Sikeston, MO
- Candlewood Suites Cape Girardeau by IHG
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Super 8 by Wyndham Perryville
- Hampton Inn Sikeston
- Quality Inn
- Comfort Inn Festus - St Louis South
- Drury Inn & Suites Jackson MO
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Hayti Caruthersville
- Days Inn and Suites by Wyndham Sikeston
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- New Orleans Inn Portageville
- Town House Inn Cape Giradreau
- Tru By Hilton Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Hampton Inn Cape Girardeau I 55 East