Find Resorts & Hotels with Spas in Big Pine Key, FL

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Check availability on Big Pine Key Resorts & Hotels with Spas

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Compare Big Pine Key Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Old Wooden Bridge Resort and Marina

2.5 star property
8.6 out of 10, Excellent, (227)
"Very nice and quiet! "
The price is AED 511
AED 942 total
includes taxes & fees
11 May - 12 May
Old Wooden Bridge Resort and Marina

Deer Run Bed & Breakfast

2.5 star property
8.0 out of 10, Very Good, (1)
"Loved it. Beautiful property."
Deer Run Bed & Breakfast

Tropical Caribbean Paradise with pool!

9.2 out of 10, Wonderful, (86)
"The camper was clean and easy to find. There’s a bath/shower house 2campsites away. We enjoyed our stay."
Tropical Caribbean Paradise with pool!

🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

10.0 out of 10, Exceptional, (4)
"The house is amazing. The rooftop views are second to none and the boating access is some of the best in the keys. And the fishing is amazing restaurants within walking distance"
🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

Banana Republics - Located in Paradise

10.0 out of 10, Exceptional, (1)
"We loved the property! The area was wonderful to walk the dog and see the key deer. The owner was very helpful with all our needs. We would absolutely stay there again!"
Banana Republics - Located in Paradise

La Tortuga: Amazing 2BR Canal Front Home on Big Pine Key, Private Pool, Spa, Dockage & Dog-Friendly

2.0 star property
La Tortuga: Amazing 2BR Canal Front Home on Big Pine Key, Private Pool, Spa, Dockage & Dog-Friendly

The most setup home in BPK TIKI HUT,POOL ,GRILL ,CANAL FRONT, FREE UNLIMITED ICE

9.2 out of 10, Wonderful, (5)
"Love,loved the pool.. neighbors were great!"
The most setup home in BPK TIKI HUT,POOL ,GRILL ,CANAL FRONT, FREE UNLIMITED ICE

Big Pine Key Unique Direct Ocean Access with 10K lbs private dock boat lift

9.2 out of 10, Wonderful, (7)
"The property was amazing. The house, canal and boat lift made our fishing and boating a breeze. I hope they're house is available next time were visiting. Also with any issues that came up which were not too many they were always available to answer questions. "
Big Pine Key Unique Direct Ocean Access with 10K lbs private dock boat lift

Serene Canal home in the Heart of the Keys

Serene Canal home in the Heart of the Keys

Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool

10.0 out of 10, Exceptional, (2)
"The house is in a nice quiet neighborhood. The road is not busy and ideal for a long walk which can be extended by adding the Monroe bridge to the walk. The house is well-maintained and was very clean. It has a well-equipped kitchen with knives that can actually be used. We loved sitting out on the verandah enjoying the beautiful ocean view and watching the bird life. The large heated pool is ideal for evening relaxation after a day's activity. We used the kayaks that were available to...
Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Big Pine Key?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Big Pine Key?
Among Expedia’s 88 accommodation options in Big Pine Key, there are 2 spa hotels.
What's there to see and do in Big Pine Key?
Enjoy all that Big Pine Key has to offer and visit Calusa Beach, Bahia Honda State Park, and Florida Keys Beaches. If you have extra time while you’re in the area, you might want to see Big Pine Key Flea Market and Cook Island.
What is a Big Pine Key spa hotel?
Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.