Find Resorts & Hotels with Spas in Big Pine Key, FL

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Check availability on Big Pine Key Resorts & Hotels with Spas

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Compare Big Pine Key Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Old Wooden Bridge Resort and Marina

2.5 star property
8.4 out of 10, Very Good, (194)
"Everything about it was great"
The price is AED 731
AED 1,189 total
includes taxes & fees
5 Mar - 6 Mar
Old Wooden Bridge Resort and Marina

Deer Run Bed & Breakfast

2.5 star property
8.0 out of 10, Very Good, (1)
"Loved it. Beautiful property."
Deer Run Bed & Breakfast

Tropical Caribbean Paradise with pool!

9.2 out of 10, Wonderful, (81)
"We just basically used this as a place to sleep so I can’t say anything about the amenities offered in the RV park such as the pool, etc. It was quiet. The only thing was it was a little difficult figuring out which RV was the right one. However, we went in the 2nd drive instead of the 1st, so that was partly our fault. Rick was responsive to questions."
Tropical Caribbean Paradise with pool!

🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

10.0 out of 10, Exceptional, (4)
"This house and location was beautiful. Large enough to entertain friends.The kitchen and bathrooms were very well stocked with high end provisions. The views were great! We watched the sunrise from the living room and went up on top to watch the sunsets. We saw dolphins in the bay from the top and played cornhole with friends. We loved the swim spa...perfect combination of hot tub and pool. Martina was the best part of it, she was the perfect host! Very accommodating and prompt to solve any...
🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

Newly Remodeled Corner House on the Water

10.0 out of 10, Exceptional, (1)
"we stayed the month of febuary. We really enjoyed the property"
Newly Remodeled Corner House on the Water

Water Views / Heated Swimming Pool / Hot Tub / Boat Dock

10.0 out of 10, Exceptional, (1)
"This home is amazing. We really enjoyed the beautiful ocean view from the house and pool. We spent a lot of time in the heated pool and hot tub. There is a great downstairs and upstairs screened in area for relaxing. The kitchen was fully stocked and all beds were comfortable. This home has a large dock for a boat. It's easy boating access to both Bay and Ocean side. It's only 6 miles away from Lone Key, which is one of the greatest reefs in the world. It great for diving or snorkeling. We'll...
Water Views / Heated Swimming Pool / Hot Tub / Boat Dock

Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool

10.0 out of 10, Exceptional, (1)
"The house is in a nice quiet neighborhood. The road is not busy and ideal for a long walk which can be extended by adding the Monroe bridge to the walk. The house is well-maintained and was very clean. It has a well-equipped kitchen with knives that can actually be used. We loved sitting out on the verandah enjoying the beautiful ocean view and watching the bird life. The large heated pool is ideal for evening relaxation after a day's activity. We used the kayaks that were available to...
Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool

The most setup home in BPK TIKI HUT,POOL ,GRILL ,CANAL FRONT, FREE UNLIMITED ICE

9.2 out of 10, Wonderful, (5)
"Love,loved the pool.. neighbors were great!"
The most setup home in BPK TIKI HUT,POOL ,GRILL ,CANAL FRONT, FREE UNLIMITED ICE

Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!

10.0 out of 10, Exceptional, (31)
"After over a decade of staying in Big Pine Key every summer, this property was by far the best. The views were absolutely stunning. The location was spectacular. So close to everything we needed. All the stores, shops, restaurants, bait shops, etc. Just a couple miles up the road if that. Diana was an amazing host and all-around kind person to communicate with. All correspondences between us were very prompt and helpful. As this was our first experience renting with VRBO, she made the whole...
Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!

Banana Republics - Located in Paradise

10.0 out of 10, Exceptional, (1)
"We loved the property! The area was wonderful to walk the dog and see the key deer. The owner was very helpful with all our needs. We would absolutely stay there again!"
Banana Republics - Located in Paradise
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Big Pine Key?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Big Pine Key?
Among Expedia’s 88 accommodation options in Big Pine Key, there are 2 spa hotels.
What's there to see and do in Big Pine Key?
Enjoy all that Big Pine Key has to offer and visit Calusa Beach, Bahia Honda State Park, and Florida Keys Beaches. If you have extra time while you’re in the area, you might want to see Big Pine Key Flea Market and Coupon Bight Aquatic Preserve.
What is a Big Pine Key spa hotel?
Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.