Find Resorts & Hotels with Spas in Sanibel, FL

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Check availability on Sanibel Resorts & Hotels with Spas

Tonight
6 Mar - 7 Mar
Tomorrow
7 Mar - 8 Mar
This weekend
7 Mar - 9 Mar
Next weekend
14 Mar - 16 Mar

Compare Sanibel Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sanibel Island Beach Resort
Exterior

Sanibel Island Beach Resort

3.0 star property
8.8 out of 10, Excellent, (1054)
"Cute hotel right on the beach with chairs. Our room was on the 2nd floor. It wasn’t completely remodeled like the pictures but was still clean and contemporary. The pool area was very nice. All staff were friendly and kind. "
The price is AED 1,465
AED 1,726 total
includes taxes & fees
1 Apr - 2 Apr
Sanibel Island Beach Resort
Island Inn
Luxury Suite, Sea View | Beach/ocean view

Island Inn

3.5 star property
9.4 out of 10, Exceptional, (1071)
"Exactly as shown and described. "
The price is AED 1,723
AED 1,921 total
includes taxes & fees
30 Mar - 31 Mar
Island Inn
Tarpon Tale Inn
Exterior

Tarpon Tale Inn

3.0 star property
9.6 out of 10, Exceptional, (378)
"This place was beautiful and very accommodating. It was a short walk or bike ride to the beach. The room had everything we needed and beach chairs, beach cart and bicycles were provided. It was right across from a coffee and ice cream shop and a nice restaurant and a gift shop. I will definitely be back to visit."
The price is AED 1,539
AED 1,716 total
includes taxes & fees
11 Mar - 12 Mar
Tarpon Tale Inn
THE Palmview AND Sandpiper Inns
Exterior

THE Palmview AND Sandpiper Inns

3.5 star property
9.4 out of 10, Exceptional, (157)
"Amazing location! Nice room! So dog friendly! Outside area so nice. Lots of amenities!"
THE Palmview AND Sandpiper Inns
Casa Ybel Resort
Aerial view

Casa Ybel Resort

2.5 star property
8.8 out of 10, Excellent, (289)
"Both the staff and resort were wonderful. Very clean place. Staff at the hotel, restaurants and pool were all very sweet and helpful. Would highly recommend this resort for families as the units are spacious, have full kitchens, and an outdoor screened in porch. The only negative was that the beach chairs are not included in the stay. You would need to rent them daily or by the week or get your own beach chairs and umbrellas from a local shop and bring them to the beach. Even with that...
Casa Ybel Resort
Sanibel Home ready for rentals ! Now reduced for April and May 2025!
A heated pool

Sanibel Home ready for rentals ! Now reduced for April and May 2025!

Sanibel Home ready for rentals ! Now reduced for April and May 2025!
Shell Island Beach Club
Beach nearby, sun loungers, beach towels

Shell Island Beach Club

2.0 star property
8.0 out of 10, Very Good, (1)
Shell Island Beach Club
Stunning Luxury villa "Sandpiper" across the street from the beach!
Beach nearby

Stunning Luxury villa "Sandpiper" across the street from the beach!

9.2 out of 10, Wonderful, (35)
"Let me start by saying that we've been to Sanibel many times - it's one of our favorite places. We've rented all over the island.Property is in a great location. It's near many restaurants, shops, markets, etc. (within a 5 min drive). Very short walk to the stunning beach. Property management company was outstanding to work with, and check-in/check-out was flawless. Unit offers everything you need.The only issue was the condition of the unit. The vertical blinds in the living room were broken...
The price is AED 1,465
AED 2,843 total
includes taxes & fees
5 Apr - 6 Apr
Stunning Luxury villa "Sandpiper" across the street from the beach!
Sundial Beach Resort & Spa
Outdoor pool, cabanas (surcharge), pool umbrellas

Sundial Beach Resort & Spa

5.0 star property
8.6 out of 10, Excellent, (2559)
"Inside are great. These condos on the west side should not be open for business. First-The construction workers parking next to you personal vehicle and using power equipment. 2nd we had no hot water, spent most of the morning changing rooms twice. The first night of dining we were sat at a table with people we didn’t know and very loud and attire was not observed. 3rd, my credit card was charged by Expedia and also by the resort, two times. I will be reporting that to my banking instruction....
The price is AED 2,200
AED 2,854 total
includes taxes & fees
23 Mar - 24 Mar
Sundial Beach Resort & Spa
Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!
Aerial view

Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!

9.6 out of 10, Exceptional, (47)
"Great location! Loved access to beach chairs, towels and bikes. Cute rental that has everything you need. Beach is walking distance. Wickies restaurant across the street is amazing!"
The price is AED 1,208
AED 1,859 total
includes taxes & fees
29 Mar - 30 Mar
Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Sanibel?
Among Expedia’s 922 accommodation options in Sanibel, there are 2 spa hotels.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you’re in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.