Find Resorts & Hotels with Spas in Sanibel, FL

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from 302 Sanibel Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Sanibel Island Beach Resort
Exterior
Sanibel Island Beach Resort
3.0 star property
8.6 out of 10, Excellent, (1079)
"Very fresh and clean. Captiva unfortunately closed due to storm damage. Let us pray these islands avoid hurricanes for a while. "
The price is AED 951
AED 1,131 total
includes taxes & fees
6 Nov - 7 Nov
Sanibel Island Beach Resort
Island Inn
Beach/ocean view
Island Inn
3.5 star property
9.4 out of 10, Exceptional, (1059)
"beautiful condo room. wish we planned to stay longer. Loved the decor and the view. the beach was amazing and loved all the shells, so amazing! Great stay here "
The price is AED 988
AED 1,079 total
includes taxes & fees
7 Nov - 8 Nov
Island Inn
Tarpon Tale Inn
Property grounds
Tarpon Tale Inn
3.0 star property
9.6 out of 10, Exceptional, (375)
"A gem! Quaint property that makes your stay enjoyable. They have everything that you need for a day at the beach/shell seeking. The chairs, umbrella, shovels, buckets, towels, and wagon are there to use. Loved it! "
Tarpon Tale Inn
THE Palmview AND Sandpiper Inns
Exterior
THE Palmview AND Sandpiper Inns
3.5 star property
9.4 out of 10, Exceptional, (142)
"Wonderful property very close to the beach, easily walkable and the optional bikes were great! Would happily stay there again and recommend to others!"
THE Palmview AND Sandpiper Inns
Casa Ybel Resort
Aerial view
Casa Ybel Resort
2.5 star property
8.8 out of 10, Excellent, (289)
"Both the staff and resort were wonderful. Very clean place. Staff at the hotel, restaurants and pool were all very sweet and helpful. Would highly recommend this resort for families as the units are spacious, have full kitchens, and an outdoor screened in porch. The only negative was that the beach chairs are not included in the stay. You would need to rent them daily or by the week or get your own beach chairs and umbrellas from a local shop and bring them to the beach. Even with that...
Casa Ybel Resort
Sanibel Home ready for rentals !
ExteriorFront1e
Sanibel Home ready for rentals !
Sanibel Home ready for rentals !
FULLY RESTORED! Rare Walkout Condo On Sanibel Beach
Ground floor condo with walk-out patio, just steps to the pool or Sanibel beach.
FULLY RESTORED! Rare Walkout Condo On Sanibel Beach
10.0 out of 10, Exceptional, (80)
"From the condo, there was a nice, easy access to the beach, and the pool was great. The condo was fully stocked. It had all the amenities of a hotel (toiletries, sheets, and towels provided) plus those of a beach condo (beach items) which was great when flying in for a vacation. "
FULLY RESTORED! Rare Walkout Condo On Sanibel Beach
SANIBEL SUN CASTLE - Splendid home, great location, heated pool, bike to beach
THE SUN CASTLE - Backyard view of house showing pool, sun deck and porches.
SANIBEL SUN CASTLE - Splendid home, great location, heated pool, bike to beach
9.8 out of 10, Exceptional, (88)
"Ralph was the most responsive and helpful host I have ever dealt with in all the years I have been using VRBO and other on line rental sites. Pool was great and view was amazing. Close to many things in Sanibel which of course is a great island and recovering from the storms but still has its charm."
SANIBEL SUN CASTLE - Splendid home, great location, heated pool, bike to beach
Stunning Luxury villa "Sandpiper" across the street from the beach!
Stunning Luxury villa "Sandpiper" across the street from the beach!
9.2 out of 10, Wonderful, (30)
"No issues at all. In fact , we got to get in early, which was nice!"
The price is AED 680
AED 1,835 total
includes taxes & fees
8 Nov - 9 Nov
Stunning Luxury villa "Sandpiper" across the street from the beach!
Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW!
your perfect private cottage entrance
Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW!
9.8 out of 10, Exceptional, (37)
"Great place - thanks so much!"
The price is AED 694
AED 1,162 total
includes taxes & fees
19 Nov - 20 Nov
Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Sanibel

Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Sanibel?
Among Expedia’s 922 accommodation options in Sanibel, there are 2 spa hotels.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you’re in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.