Find Luxury Hotels in Sanibel, FL

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Pick from 15 Sanibel Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Sundial Beach Resort & Spa
5.0 star property
8.6 out of 10, Excellent, (2557)
"Nice hotel"
Sundial Beach Resort & Spa
Seaside Inn
3.5 star property
8.8 out of 10, Excellent, (1299)
"Main issue was that the door does not have a toddler proof lock. Like there is no chain or bar at top. So basically my toddler could open the door and run outside to the pool at will. So that was very stressful. They were hard to get ahold of at front desk but besides those things amenities were nice and we enjoyed the trip"
Seaside Inn
Sunset Beach Inn
2.0 star property
8.2 out of 10, Very Good, (1000)
"We enjoyed our stay very much . We loved being so close to the beautiful beach. The room was a bit outdated but very clean and comfortable."
Sunset Beach Inn
Anchor Inn and Cottages
3.0 star property
8.4 out of 10, Very Good, (606)
"Very nice stay - the host was exceptionally friendly and it is a peaceful place - great location and the room was exactly what we were looking for. Nice mini-lake with lots of nature behind the property. Would highly recommend this place!"
Anchor Inn and Cottages
West Wind Inn
3.0 star property
8.8 out of 10, Excellent, (1001)
"Nice"
West Wind Inn
Sanibel Inn
3.5 star property
8.8 out of 10, Excellent, (1000)
"The property is rather old but the staff and their attention to details and humble approach makes this place remarkable. I have asked for some modifications in my reservation and they were very caring about it, if you are looking for peace then this is the place. It has everyone that you might need for unwinding. "
Sanibel Inn
Island Inn
3.5 star property
9.4 out of 10, Exceptional, (1059)
"beautiful condo room. wish we planned to stay longer. Loved the decor and the view. the beach was amazing and loved all the shells, so amazing! Great stay here "
The price is AED 988
AED 1,079 total
includes taxes & fees
7 Nov - 8 Nov
Island Inn
Gulf Breeze Cottages
2.0 star property
9.4 out of 10, Exceptional, (197)
"Perfect, private getaway, steps from the beach. Already booked a week for next year. "
Gulf Breeze Cottages
Casa Ybel Resort
2.5 star property
8.8 out of 10, Excellent, (289)
"Both the staff and resort were wonderful. Very clean place. Staff at the hotel, restaurants and pool were all very sweet and helpful. Would highly recommend this resort for families as the units are spacious, have full kitchens, and an outdoor screened in porch. The only negative was that the beach chairs are not included in the stay. You would need to rent them daily or by the week or get your own beach chairs and umbrellas from a local shop and bring them to the beach. Even with that...
Casa Ybel Resort
Song of the Sea
2.0 star property
9.0 out of 10, Wonderful, (1001)
"I liked the proximity to the beach. I would have liked more restaurants within walking distance. The rooms were decent and clean, but the beds were a bit uncomfortable. "
Song of the Sea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in Sanibel?
Use Expedia and let us help you arrange a flight to Southwest Florida Intl. Airport (RSW) airport or Punta Gorda Airport (PGD) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Sanibel offers. During your visit, you might want to enjoy the beaches and sunsets which Sanibel is known for.
How many luxury hotels will I find in Sanibel?
Lie in the lap of luxury during your getaway to Sanibel in one of Expedia’s 6 luxury hotels.
When can I expect good weather in Sanibel?
Planning for the weather is an important factor for making your trip to Sanibel a success, especially when you’re splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 68°F. The rainiest months in Sanibel are August, September, July, and June, with each month seeing an average of 9 inches of rainfall.
What's there to see and do in Sanibel?
Enjoy all that Sanibel has to offer when you visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have a little extra time during your trip, you might want to check out Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.