Photo by Michele Butts

Find Luxury Hotels in La Mesa, CA

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Check availability on La Mesa Luxury Hotels

Compare La Mesa Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1000)
"Love it ❤️breakfast is wonderful no complaints and its changes every day. They are in the middle of remodeling but didn't disturb us at all."
The price is AED 434
AED 477 total
includes taxes & fees
23 Mar - 24 Mar
Best Western Plus La Mesa San Diego

Motel 6 La Mesa, CA

2.0 star property
7.2 out of 10, Good, (1002)
"I was really shocked; I've stayed at this location several times in the past. My room was clean for the most part (floor not clean). The bathroom was remolded, with new bathtub, the sick area was new as well. Love the bedding, and phone area was also an upgrade. Check in was very easy, and took no time at all, I needed a low-level room and was accommodated. Very close to food places, and 7-11, and other stores, freeway access wasn't bad either. For a 1 night say It wasn't bad at all."
The price is AED 356
AED 392 total
includes taxes & fees
30 Mar - 31 Mar
Motel 6 La Mesa, CA

Heritage Inn La Mesa

2.0 star property
6.2 out of 10, (1004)
"It’s pretty much the same. There empting the trash more often."
The price is AED 265
AED 292 total
includes taxes & fees
13 Mar - 14 Mar
Heritage Inn La Mesa

Holiday Inn Express La Mesa Near SDSU by IHG

2.5 star property
8.4 out of 10, Very Good, (265)
"Great place "
The price is AED 481
AED 530 total
includes taxes & fees
16 Mar - 17 Mar
Holiday Inn Express La Mesa Near SDSU by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in La Mesa?
Use Expedia and let us help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that La Mesa has to offer. During your visit, you might want to enjoy the entertainment which La Mesa is known for.
How many luxury hotels can I expect to find in La Mesa?
Lie in the lap of luxury during your getaway to La Mesa in one of Expedia’s 6 luxury hotels.
When can I expect good weather in La Mesa?
Planning for the weather is an important factor for making your trip to La Mesa a success, especially when you’re splurging. The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo, and Mission Bay. If you have a bit of extra time while you’re in the area, you might want to check out Mission Beach and San Ysidro Border Crossing.
How can I get around La Mesa?
It’s easier to get around town in style when you know your options. Nearby metro stations include La Mesa Boulevard Station, Spring St Trolley Station, and 70th St. Trolley Station.