Photo by Michele Butts

Find Resorts & Hotels with Spas in La Mesa, CA

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Check availability on La Mesa Resorts & Hotels with Spas

Compare La Mesa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1015)
"Quiet & close to shopping."
The price is AED 281
AED 310 total
includes taxes & fees
16 Apr - 17 Apr
Heritage Inn La Mesa

Motel 6 La Mesa, CA - San Diego

2.0 star property
7.4 out of 10, Good, (879)
"Super polite staff."
The price is AED 327
AED 360 total
includes taxes & fees
20 Apr - 21 Apr
Motel 6 La Mesa, CA - San Diego

Holiday Inn Express La Mesa Near SDSU by IHG

3.0 star property
8.4 out of 10, Very Good, (289)
"We arrived 10 mins before check in and was told expedia overbooked our room, double king suite, so we didn't get the room we booked. We didn't check in until about 3:20. The staff was accomodating and put us in 2 rooms side by side, a little inconvient for us logistically, but it was okay. The walls are thin, you can hear every step and noise from the next rooms and in the hall. The hotel was fully booked the weekend we were there and it seemed there were people outside in the parking lot and...
The price is AED 466
AED 514 total
includes taxes & fees
20 Apr - 21 Apr
Holiday Inn Express La Mesa Near SDSU by IHG

Motel 6 La Mesa, CA

2.0 star property
7.2 out of 10, Good, (1002)
"One of the best motels I’ve stayed at while visiting San Diego! The front desk staff were incredibly friendly and polite, making check-in a breeze. The rooms appeared to be recently remodeled. I also appreciated the convenience of having a mini refrigerator and microwave in the room. Overall, a great stay—I would definitely book this location again! "
The price is AED 386
AED 424 total
includes taxes & fees
20 Apr - 21 Apr
Motel 6 La Mesa, CA

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1005)
" Easy to get in"
The price is AED 408
AED 449 total
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus La Mesa San Diego

***Luxurious VRBO Estate Home -Sumptuous Views - Resort like!!!***

9.8 out of 10, Exceptional, (119)
"There were 4 adults staying at this home. Clean rooms. Not clear until you read all the fine print was that the owner lives on main floor and the rental was for lower level space. One bathroom was also entrance into the home which also had washer and dryer in this space. Also not clear in description was the very steep driveway so not able to go for a walk but had to drive somewhere. Townhouse on the property was rented to a really nice couple with a young boy and an infant at same time we...
***Luxurious VRBO Estate Home -Sumptuous Views - Resort like!!!***

Zen Resort 🏡 hilltop, heated Infinity Pool/Spa/Casita & 360° views ⛰ 🌅 🌆 🎆 !

10.0 out of 10, Exceptional, (10)
"We had the limit of guests. All adults. It still felt spacious and we all enjoyed our stay! "
Zen Resort 🏡 hilltop, heated Infinity Pool/Spa/Casita & 360° views ⛰ 🌅 🌆 🎆 !

Luxurious Estate Home-Sumptuous Views - Resort Like!!!

9.6 out of 10, Exceptional, (112)
"It was a comfortable place to have a nice visit with my son. "
Luxurious Estate Home-Sumptuous Views - Resort Like!!!

Pool Side Safari Cabin

10.0 out of 10, Exceptional, (53)
"The Safari Cabin is a beautiful, relaxing place to stay. It has a lot of room and is well stocked to make your stay feel like home. Sandy is fantastic and very helpful. Will stay here again when back in San Diego "
Pool Side Safari Cabin

Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground

10.0 out of 10, Exceptional, (29)
"We spent a weekend celebrating my mother's 84th birthday in the house: eleven of us ranging in age from 84 to 14 years old. The house was spacious, clean and well appointed. The backyard was amazing--pool, hot tub, sauna, games, ample seating and more! The arcade was a huge hit with our family as well.The kitchen had all of the plates, pots, etc. we needed. The host, Alvin, was incredible. The best host we have ever encountered. "
Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in La Mesa?
Treat yourself to some pampering and book a hotel with a spa. Travelers recommend the gourmet restaurants in La Mesa. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in La Mesa?
Among Expedia’s 147 accommodation options in La Mesa, there are 4 spa hotels.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo, and Mission Bay. If you have extra time while you’re in the area, you might want to stop by Petco Park and Port of San Diego.
What is a La Mesa spa hotel?
Spa hotels in La Mesa provide lodging and have an on-site spa which offers services such as facials and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.