Photo by Michele Butts

Find Resorts & Hotels with Spas in La Mesa, CA

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Check availability on La Mesa Resorts & Hotels with Spas

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Compare La Mesa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Heritage Inn La Mesa

2.0 star property
6.4 out of 10, (1217)
"Everyone is so helpful "
The price is AED 281
AED 310 total
includes taxes & fees
6 Apr - 7 Apr
Heritage Inn La Mesa

Motel 6 La Mesa, CA - San Diego

2.0 star property
7.4 out of 10, Good, (877)
"I am mostly worried about bed bugs and safety. I have gone to this hotel a few times in different rooms and I did not find any bed bugs, nor have I brought any home. The area is relatively safe and they have security cameras. I traveled with my dogs and the staff are always nice."
The price is AED 305
AED 336 total
includes taxes & fees
3 Apr - 4 Apr
Motel 6 La Mesa, CA - San Diego

Holiday Inn Express La Mesa Near SDSU by IHG

2.5 star property
8.4 out of 10, Very Good, (276)
"We had a nice stay."
The price is AED 466
AED 514 total
includes taxes & fees
20 Apr - 21 Apr
Holiday Inn Express La Mesa Near SDSU by IHG

Motel 6 La Mesa, CA

2.0 star property
7.2 out of 10, Good, (1025)
"Customer service was excellent . Patient and compromising when needed "
The price is AED 356
AED 392 total
includes taxes & fees
6 Apr - 7 Apr
Motel 6 La Mesa, CA

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1077)
"It was a great an quite stay staff very helpful "
The price is AED 394
AED 433 total
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus La Mesa San Diego

***Luxurious VRBO Estate Home -Sumptuous Views - Resort like!!!***

9.8 out of 10, Exceptional, (119)
"There were 4 adults staying at this home. Clean rooms. Not clear until you read all the fine print was that the owner lives on main floor and the rental was for lower level space. One bathroom was also entrance into the home which also had washer and dryer in this space. Also not clear in description was the very steep driveway so not able to go for a walk but had to drive somewhere. Townhouse on the property was rented to a really nice couple with a young boy and an infant at same time we...
***Luxurious VRBO Estate Home -Sumptuous Views - Resort like!!!***

Zen Resort 🏡 hilltop, heated Infinity Pool/Spa/Casita & 360° views ⛰ 🌅 🌆 🎆 !

10.0 out of 10, Exceptional, (10)
"We had the limit of guests. All adults. It still felt spacious and we all enjoyed our stay! "
Zen Resort 🏡 hilltop, heated Infinity Pool/Spa/Casita & 360° views ⛰ 🌅 🌆 🎆 !

Luxurious Estate Home-Sumptuous Views - Resort Like!!!

9.6 out of 10, Exceptional, (111)
"The views and peacefulness of this location made it a great month-long stay for my spouse and me. Jeff met us on our arrival to give us a tour of the unit and was very communicative during the stay. He helped with a few things we needed, which we appreciated very much.Some of the nice things about the unit include: - Mountain View outside the dining room window- Plenty of place settings, pots, and pans- The outdoor patio space, garden, fruit trees, seating options- Number of towels- Closet...
Luxurious Estate Home-Sumptuous Views - Resort Like!!!

Pool Side Safari Cabin

10.0 out of 10, Exceptional, (53)
"The Safari Cabin is a beautiful, relaxing place to stay. It has a lot of room and is well stocked to make your stay feel like home. Sandy is fantastic and very helpful. Will stay here again when back in San Diego "
Pool Side Safari Cabin

Spacious Home Away From Home

9.2 out of 10, Wonderful, (63)
"Love the house. Very clean and spacious. Close to everything. "
Spacious Home Away From Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in La Mesa?
Treat yourself to some pampering and book a hotel with a spa. Travelers recommend the gourmet restaurants in La Mesa. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in La Mesa?
Among Expedia’s 147 accommodation options in La Mesa, there are 4 spa hotels.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo, and Mission Bay. If you have extra time while you’re in the area, you might want to stop by Petco Park and Port of San Diego.
What is a La Mesa spa hotel?
Spa hotels in La Mesa provide lodging and have an on-site spa which offers services such as facials and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.