Find Resorts & Hotels with Spas in Port Saint Lucie, FL

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Pick from 200 Port Saint Lucie Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

TownePlace Suites by Marriott Port St. Lucie I-95
Pool
TownePlace Suites by Marriott Port St. Lucie I-95
2.5 star property
9.4 out of 10, Exceptional, (826)
"Sooo quiet. Clean. Safe. Staff were super nice and helpful. Room is awesome with real fridge that is cold, microwave, stove and dishwasher. Lighting was great and AC was cold and quiet. "
The price is AED 393
AED 435 total
includes taxes & fees
15 Dec - 16 Dec
TownePlace Suites by Marriott Port St. Lucie I-95
Hampton Inn & Suites Port St. Lucie, West
Exterior
Hampton Inn & Suites Port St. Lucie, West
2.5 star property
8.8 out of 10, Excellent, (1000)
"Great spot"
The price is AED 309
AED 342 total
includes taxes & fees
16 Dec - 17 Dec
Hampton Inn & Suites Port St. Lucie, West
Homewood Suites by Hilton Port Saint Lucie-Tradition
Exterior
Homewood Suites by Hilton Port Saint Lucie-Tradition
3.0 star property
8.8 out of 10, Excellent, (1002)
"Property was very clean, pool was amazing just missing towels. Staff was very helpful and kind."
The price is AED 372
AED 410 total
includes taxes & fees
15 Dec - 16 Dec
Homewood Suites by Hilton Port Saint Lucie-Tradition
Residence Inn by Marriott Port St. Lucie
Exterior
Residence Inn by Marriott Port St. Lucie
3.0 star property
9.2 out of 10, Wonderful, (1025)
"Absolutely love this hotel close to a lot "
The price is AED 378
AED 416 total
includes taxes & fees
15 Dec - 16 Dec
Residence Inn by Marriott Port St. Lucie
Mainstay Suites at PGA Village
Exterior
Mainstay Suites at PGA Village
2.5 star property
6.6 out of 10, (635)
"Excellent as always! The comforters are super comfy and rooms are spacious and full size fridge. Great to spend a long weekend and be able to cook and not spend tons of money eating out and all. "
The price is AED 395
AED 435 total
includes taxes & fees
28 Nov - 29 Nov
Mainstay Suites at PGA Village
Tru by Hilton Port St. Lucie Tradition
Exterior
Tru by Hilton Port St. Lucie Tradition
2.5 star property
9.2 out of 10, Wonderful, (404)
"It was exactly what we were looking for. "
The price is AED 328
AED 362 total
includes taxes & fees
15 Dec - 16 Dec
Tru by Hilton Port St. Lucie Tradition
Sleep Inn at PGA Village
Exterior
Sleep Inn at PGA Village
2.5 star property
6.6 out of 10, (264)
"The property was a solid good place to stay the rates were reasonable the staff was effective and pleasurable the beds were excellent to sleep on . Clean linens . The only aspect of the room that was not very good was floors were a little grimmy. I took some of the extra towels and cleaned them it took about 10 minutes. Other than that I had a very good stay . I would stay again ."
The price is AED 291
AED 320 total
includes taxes & fees
8 Dec - 9 Dec
Sleep Inn at PGA Village
Best Western Port St. Lucie
Pool
Best Western Port St. Lucie
2.5 star property
8.6 out of 10, Excellent, (1005)
"We have stayed here multiple times. The rooms are nice and the price is reasonable. It's in a good location for our annual migration to the Florida Keys. Big bonus is the Casa Amigos restaurant just next door!"
The price is AED 389
AED 436 total
includes taxes & fees
24 Nov - 25 Nov
Best Western Port St. Lucie
Sheraton PGA Vacation Resort, Port St. Lucie
Pool
Sheraton PGA Vacation Resort, Port St. Lucie
3.5 star property
9.0 out of 10, Wonderful, (593)
"Very nice clean room with a fully equipped kitchen. Pleasant checkin with staff. Property is immaculate and very well kept."
The price is AED 378
AED 418 total
includes taxes & fees
8 Dec - 9 Dec
Sheraton PGA Vacation Resort, Port St. Lucie
Beautiful home with pool-minutes to beaches, golf courses & Clover,Mets Stadium
Pool
Beautiful home with pool-minutes to beaches, golf courses & Clover,Mets Stadium
9.8 out of 10, Exceptional, (26)
"Great place."
Beautiful home with pool-minutes to beaches, golf courses & Clover,Mets Stadium
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Port Saint Lucie?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend the restaurants in Port Saint Lucie. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Port Saint Lucie?
Among Expedia’s 575 accommodation options in Port Saint Lucie, there is 1 spa hotel.
What's there to see and do in Port Saint Lucie?
Take in the sights and attractions that Port Saint Lucie offers with a visit to Port St. Lucie Botanical Gardens, The Saints at Port St. Lucie Golf Course, and River Park Marina. If you have some spare time during your trip, you might want to check out Clover Park and PGA Village.
What is a Port Saint Lucie spa hotel?
Spa hotels in Port Saint Lucie provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.