Find 4 Star Hotels in Port Saint Lucie, FL
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Port Saint Lucie 4 Star Hotels
Compare Port Saint Lucie 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Luxury 5 Bedroom Villa on Champions Gate Resort, Orlando Villa 1756
Luxury 5 Bedroom Villa on Champions Gate Resort, Orlando Villa 1756
2.0 out of 10, (1)

Boho Chic Retreat
Boho Chic Retreat
10.0 out of 10, Exceptional, (5)
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Port Saint Lucie
Escape to Port Saint Lucie! Enjoy its sports, culture, and food.

Explore a world of travel with Expedia
Explore a world of travel with Expedia
Port Saint Lucie Hotels by Star Rating
Stay near popular Port Saint Lucie attractions
- Hotels near Clover Park
- Hotels near PGA Village
- Hotels near Port St. Lucie Botanical Gardens
- Hotels near The Saints at Port St. Lucie Golf Course
- Hotels near River Park Marina
- Hotels near St. Lucie Shooting Center
- Hotels near Veterans Memorial Park
- Hotels near Superplay USA
- Hotels near Savannas Preserve State Park
- Hotels near PGA Center for Golf Learning and Performance
- Hotels near Oxbow Eco-Center
- Hotels near Treasure Coast Model Railroads
- Hotels near Paleo Hammock Preserve
- Hotels near Spruce Bluff Preserve
- Hotels near Lake Okeechobee
- Hotels near Bathtub Beach
- Hotels near Stuart Beach
- Hotels near Fort Pierce Beach
- Hotels near Roger Dean Stadium
- Hotels near McKee Botanical Garden
More Hotel Options in Port Saint Lucie
- Adventure Hotels in Port Saint Lucie
- Beach Hotels in Port Saint Lucie
- Boutique Hotels in Port Saint Lucie
- Business Hotels in Port Saint Lucie
- Cheap Hotels in Port Saint Lucie
- Family Hotels in Port Saint Lucie
- Golf Hotels in Port Saint Lucie
- Green Hotels in Port Saint Lucie
- Historic Hotels in Port Saint Lucie
- Hotel Wedding Venues in Port Saint Lucie
- Hotel with a Concierge in Port Saint Lucie
- Hotels with Bars in Port Saint Lucie
- Hotels with Free Parking in Port Saint Lucie
- Hotels with Hot Tubs in Port Saint Lucie
- Hotels with WiFi in Port Saint Lucie
- Hotels with a Pool in Port Saint Lucie
- Hotels with smoking rooms in Port Saint Lucie
- Luxury Hotels in Port Saint Lucie
- Pet-friendly Hotels in Port Saint Lucie
- Resorts & Hotels with Spas in Port Saint Lucie
- Romantic Hotels in Port Saint Lucie
- Shopping Hotels in Port Saint Lucie
More Accommodation Types in Port Saint Lucie
Explore more hotels
- TownePlace Suites by Marriott Port St. Lucie I-95
- Sheraton PGA Vacation Resort, Port St. Lucie
- Holiday Inn Express & Suites Port St. Lucie West by IHG
- Sleep Inn at PGA Village
- Residence Inn by Marriott Port St. Lucie
- Right Direction Rentals
- Cozy Oasis
- Sandpiper Bay All-Inclusive, Trademark Collection by Wyndham
- Luxurious Pool Cottage Sleep 2
- Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach
- Great Pool Home with Movie Room !
- Luxury Riverfront Home Pool Dock 20 Min To beach 15 Min to Mets Stadium Pets OK
- Beautiful Water Front home in Port St Lucie FL
- Beach like you've never seen! Heated pool/spa!
- Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach!
- Beautiful, spacious, family friendly private home! one
- Clean & Comfortable 3-bedroom, 2-bath home! Only 2 bedrooms are for rent.
- A Slice of Paradise pool and pool table
- Private 1 bedroom apt/full kitchen/big shower.
- The Perfect Place now with washer and dryer.