Find hotels in Otay Mesa, San Diego from AED 129

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Discover 4,428 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Rosarito Beach Hotel
3.0 star property
8.0 out of 10, Very Good, (1037)
"We liked the room and the view but one thing we couldn’t find was ice."
The price is AED 400
AED 452 total
includes taxes & fees
24 Nov - 25 Nov
Rosarito Beach Hotel
Hotel Festival Plaza Playas Rosarito
3.0 star property
7.2 out of 10, Good, (1357)
"Great Service Great Experience…"
The price is AED 290
AED 328 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Festival Plaza Playas Rosarito
SureStay Hotel by Best Western Chula Vista San Diego Bay
3.0 star property
7.6 out of 10, Good, (1292)
"Staff was so friendly and made sure everything was ok. There where a lot of food options near the hotel "
The price is AED 281
AED 305 total
includes taxes & fees
17 Dec - 18 Dec
SureStay Hotel by Best Western Chula Vista San Diego Bay
The Rambler Motel
3.0 star property
9.0 out of 10, Wonderful, (1850)
"Great "
The price is AED 364
AED 421 total
includes taxes & fees
24 Nov - 25 Nov
The Rambler Motel
Hotel Corona Plaza
3.0 star property
6.6 out of 10, (1456)
"Great staff and convient area"
The price is AED 214
AED 242 total
includes taxes & fees
5 Dec - 6 Dec
Hotel Corona Plaza
Hotel Wellintown
3.0 star property
9.2 out of 10, Wonderful, (634)
"Great location close to many restaurants and shops "
The price is AED 242
AED 293 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Wellintown
Hotel West Plaza
3.0 star property
9.4 out of 10, Exceptional, (309)
"Nice hotel, u can go anywhre from here"
The price is AED 260
AED 315 total
includes taxes & fees
24 Nov - 25 Nov
Hotel West Plaza
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel
2.5 star property
7.4 out of 10, Good, (1328)
"Good quiet convenient "
The price is AED 393
AED 435 total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel
Quartz Hotel & SPA
4.5 star property
9.2 out of 10, Wonderful, (1012)
"It’s always a pleasure to stay there, such nice atmosphere and place. "
The price is AED 588
AED 664 total
includes taxes & fees
25 Nov - 26 Nov
Quartz Hotel & SPA
Del Mar Inn Rosarito
3.0 star property
8.0 out of 10, Very Good, (1001)
"Good"
The price is AED 283
AED 320 total
includes taxes & fees
4 Dec - 5 Dec
Del Mar Inn Rosarito
Ibis Tijuana Zona Rio
3.0 star property
8.4 out of 10, Very Good, (1508)
"DEJAR MAS AGUA PARA BEBER EN EL CUARTO"
The price is AED 261
AED 294 total
includes taxes & fees
8 Dec - 9 Dec
Ibis Tijuana Zona Rio
Hercor Hotel - Urban Boutique
3.0 star property
8.4 out of 10, Very Good, (1048)
"There were limited parking area inside the hotel. There were lots of homeless people in the late evening and in the morning too."
The price is AED 378
AED 410 total
includes taxes & fees
5 Dec - 6 Dec
Hercor Hotel - Urban Boutique
Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
7.6 out of 10, Good, (721)
"Rooms were comfortable and excellent management."
The price is AED 257
AED 290 total
includes taxes & fees
15 Dec - 16 Dec
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Hotel Grand One Plaza
3.0 star property
8.6 out of 10, Excellent, (941)
"I love the terrazzo,the top of building it gourgeos 😍😍😍"
The price is AED 243
AED 294 total
includes taxes & fees
24 Nov - 25 Nov
Hotel Grand One Plaza
Hotel Castillos del Mar
3.0 star property
6.6 out of 10, (1005)
"The property was good. The only thing is that they are very limited on power outlets and there was areas that weren't cleaned. But the view was beautiful and the service was great. "
The price is AED 210
AED 237 total
includes taxes & fees
5 Dec - 6 Dec
Hotel Castillos del Mar
La Quinta Inn by Wyndham San Diego Chula Vista
2.5 star property
8.6 out of 10, Excellent, (1048)
"I loved the stay nice and cozy "
The price is AED 372
AED 403 total
includes taxes & fees
2 Dec - 3 Dec
La Quinta Inn by Wyndham San Diego Chula Vista
Hotel Real del Río
3.5 star property
9.2 out of 10, Wonderful, (1005)
"After looking at different hotel this place was the best decision ever. "
The price is AED 388
AED 439 total
includes taxes & fees
24 Nov - 25 Nov
Hotel Real del Río
Hotel Revolución
3.0 star property
7.2 out of 10, Good, (561)
"Is an old property but super located"
The price is AED 129
AED 146 total
includes taxes & fees
25 Nov - 26 Nov
Hotel Revolución
Holiday Inn Tijuana Zona Rio, an IHG Hotel
3.5 star property
8.6 out of 10, Excellent, (1326)
"location and service"
The price is AED 264
AED 303 total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Tijuana Zona Rio, an IHG Hotel
Hotel Palmeras Chula Vista
2.0 star property
7.0 out of 10, Good, (1686)
"Bums"
The price is AED 264
AED 291 total
includes taxes & fees
24 Nov - 25 Nov
Hotel Palmeras Chula Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Quality Suites San Diego Otay Mesa is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.