Find hotels in Otay Mesa, San Diego from AED 237

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Discover 4,529 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel

2.5 star property
7.6 out of 10, Good, (1367)
"We had good service "
The price is AED 437
AED 492 total
includes taxes & fees
26 Jan - 27 Jan
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1001)
"I had a very comfortable stay. Close to Cbx."
The price is AED 360
AED 405 total
includes taxes & fees
28 Jan - 29 Jan
Quality Suites San Diego Otay Mesa

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1101)
"Clean, very kind and helpful receptionists, gave us a room on the floor we wanted with a nice view since we had an upgrade option"
The price is AED 237
AED 300 total
includes taxes & fees
2 Feb - 3 Feb
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.8 out of 10, Good, (1001)
"Excellent"
The price is AED 322
AED 354 total
includes taxes & fees
2 Feb - 3 Feb
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.4 out of 10, Good, (1001)
"The greatest place ever "
The price is AED 307
AED 338 total
includes taxes & fees
26 Jan - 27 Jan
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1001)
"Large rooms"
The price is AED 455
AED 501 total
includes taxes & fees
26 Jan - 27 Jan
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (208)
"Clean "
The price is AED 610
AED 672 total
includes taxes & fees
26 Jan - 27 Jan
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1128)
"Excellent location, great hotel. The beds were so comfortable and they offered a good breakfast for free of omelets made to my specifications. Highly recommended. "
The price is AED 610
AED 672 total
includes taxes & fees
2 Feb - 3 Feb
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.2 out of 10, (1005)
"Would be nice if it offered breakfast or microwave in the room"
The price is AED 242
AED 267 total
includes taxes & fees
26 Jan - 27 Jan
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1013)
"One of the cleanest places I have stayed at."
The price is AED 452
AED 500 total
includes taxes & fees
26 Jan - 27 Jan
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.6 out of 10, Good, (1308)
"I love the service Keneth help me through my stay he was helpful, patien, understanding and always made sure i understood everything thank you so much keneth"
The price is AED 387
AED 426 total
includes taxes & fees
2 Feb - 3 Feb
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

2.5 star property
8.6 out of 10, Excellent, (1098)
"Great choice"
The price is AED 340
AED 374 total
includes taxes & fees
9 Feb - 10 Feb
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (847)
"The outside of the property smelled like sewage and the inside of the room could have been cleaner. The staff was very nice. "
The price is AED 257
AED 290 total
includes taxes & fees
23 Jan - 24 Jan
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1001)
"Place is safe, quiet, rooms are big and comfortable, a little outdated but clean, had problems with the remote control, it’s a pain trying to use it but I stayed to rest not to watch tv so not a big issue. Fast food restaurant right in front. "
The price is AED 288
AED 324 total
includes taxes & fees
2 Feb - 3 Feb
Valli Hi Motel

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1066)
"Muy limpio el cuarto en general todo muy bien y el desayuno muy completo y gran variedad excelente estancia Gracias a todo el personal "
The price is AED 309
AED 348 total
includes taxes & fees
29 Jan - 30 Jan
Best Western Americana Inn

Chula Vista Inn

2.5 star property
6.2 out of 10, (1003)
"My teenage daughter and I got a late start heading to Tijuana. We ended up reaching the boarder around 1am and checked in to get some sleep before crossing in the morning. Staff was so kind. Rooms are spacious, but not fancy. They do have a microwave and a mini fridge which was great as we had left overs. We'd stay again before or after crossing."
The price is AED 298
AED 327 total
includes taxes & fees
23 Jan - 24 Jan
Chula Vista Inn

Quality Inn

2.5 star property
7.6 out of 10, Good, (811)
"It was a very pleasant stay! Will be back soon."
The price is AED 262
AED 288 total
includes taxes & fees
29 Jan - 30 Jan
Quality Inn

Days Inn by Wyndham Chula Vista/San Diego

2.5 star property
6.2 out of 10, (790)
"Good pricing "
The price is AED 250
AED 275 total
includes taxes & fees
23 Jan - 24 Jan
Days Inn by Wyndham Chula Vista/San Diego

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1684)
"Everything was good"
The price is AED 294
AED 323 total
includes taxes & fees
23 Jan - 24 Jan
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1080)
"Will return here"
The price is AED 325
AED 358 total
includes taxes & fees
4 Feb - 5 Feb
Hercor Hotel - Urban Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.