Find 4 Star Hotels in Otay Mesa, CA from AED 379

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Compare Otay Mesa 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
8.2 out of 10, Very Good, (1058)
"I recently stayed at this property over the weekend and enjoyed it. The staff was friendly, property was well decorated and our rooms were clean. I would recommend this property and stay again the future when visiting San Diego. "
The price is AED 528
AED 577 total
includes taxes & fees
24 Nov - 25 Nov
DoubleTree by Hilton Hotel San Diego - Mission Valley
Wyndham San Diego Bayside
4.0 star property
8.2 out of 10, Very Good, (5523)
"This hotel was very comfortable. Most of the staff was very accommodating. One desk personal was a bit rude and made us uncomfortable. The restaurants were great and the transportation from the airport was easy and fast. We really enjoyed our stay. "
The price is AED 559
AED 618 total
includes taxes & fees
29 Nov - 30 Nov
Wyndham San Diego Bayside
Hyatt Regency Mission Bay Spa and Marina
4.0 star property
8.6 out of 10, Excellent, (1439)
"Daily resort fee and parking fee too high, price for daily resort nor parking wasnt listed on listing. "
The price is AED 559
AED 780 total
includes taxes & fees
17 Dec - 18 Dec
Hyatt Regency Mission Bay Spa and Marina
Hard Rock Hotel San Diego
4.0 star property
8.8 out of 10, Excellent, (2510)
"I love how clean the hotel room was and the mini fridge was awesome."
The price is AED 643
AED 866 total
includes taxes & fees
22 Dec - 23 Dec
Hard Rock Hotel San Diego
Manchester Grand Hyatt San Diego
4.0 star property
9.0 out of 10, Wonderful, (2865)
"Wonderful stay!"
The price is AED 621
AED 862 total
includes taxes & fees
25 Nov - 26 Nov
Manchester Grand Hyatt San Diego
Sheraton San Diego Hotel and Marina
4.0 star property
8.0 out of 10, Very Good, (2476)
"Clean, great view of bay, very helpful staff"
The price is AED 455
AED 614 total
includes taxes & fees
27 Nov - 28 Nov
Sheraton San Diego Hotel and Marina
Palihotel San Diego
4.0 star property
8.6 out of 10, Excellent, (961)
"Love it "
The price is AED 404
AED 550 total
includes taxes & fees
19 Dec - 20 Dec
Palihotel San Diego
Marriott Marquis San Diego Marina
4.0 star property
9.0 out of 10, Wonderful, (1611)
"Marina right behind, severely dinning options in walking distance "
The price is AED 591
AED 784 total
includes taxes & fees
27 Nov - 28 Nov
Marriott Marquis San Diego Marina
Town and Country San Diego
4.0 star property
8.4 out of 10, Very Good, (1103)
"The property had a lot of activities for children and adults. Very friendly staff and great food options."
The price is AED 555
AED 696 total
includes taxes & fees
24 Nov - 25 Nov
Town and Country San Diego
Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
8.8 out of 10, Excellent, (1129)
"San Diego was fun and the hotel was great"
The price is AED 715
AED 899 total
includes taxes & fees
19 Dec - 20 Dec
Embassy Suites by Hilton San Diego Bay Downtown
Paradise Point Resort & Spa
4.0 star property
8.6 out of 10, Excellent, (1934)
"I like that the rooms were separate bungalows."
The price is AED 488
AED 720 total
includes taxes & fees
22 Nov - 23 Nov
Paradise Point Resort & Spa
Sheraton Mission Valley San Diego Hotel
4.0 star property
8.4 out of 10, Very Good, (1215)
"Nice"
The price is AED 379
AED 421 total
includes taxes & fees
24 Nov - 25 Nov
Sheraton Mission Valley San Diego Hotel
Hilton San Diego Mission Valley
4.0 star property
7.8 out of 10, Good, (1320)
"Very good location, nice breakfast option"
The price is AED 459
AED 511 total
includes taxes & fees
28 Nov - 29 Nov
Hilton San Diego Mission Valley
San Diego Marriott Gaslamp Quarter
4.0 star property
8.6 out of 10, Excellent, (1228)
"."
The price is AED 528
AED 587 total
includes taxes & fees
22 Dec - 23 Dec
San Diego Marriott Gaslamp Quarter
San Diego Marriott Mission Valley
4.0 star property
8.6 out of 10, Excellent, (1000)
"Great stay and rather close to many things . Would definitely stay again and recommend "
The price is AED 493
AED 544 total
includes taxes & fees
24 Nov - 25 Nov
San Diego Marriott Mission Valley
Omni San Diego Hotel
4.0 star property
9.0 out of 10, Wonderful, (1757)
"This place is great"
The price is AED 559
AED 780 total
includes taxes & fees
26 Nov - 27 Nov
Omni San Diego Hotel
Lafayette Hotel & Club
4.0 star property
9.2 out of 10, Wonderful, (445)
"Very Nice place 😍Love it!"
The price is AED 735
AED 810 total
includes taxes & fees
22 Nov - 23 Nov
Lafayette Hotel & Club
Hilton San Diego Bayfront
4.0 star property
8.4 out of 10, Very Good, (1526)
"Room was still a little dirty after check in. Cleaning staff was friendly and re cleaned room for us. Overall a good stay. "
The price is AED 462
AED 688 total
includes taxes & fees
22 Dec - 23 Dec
Hilton San Diego Bayfront
Legacy Resort Hotel & Spa
4.0 star property
9.2 out of 10, Wonderful, (2901)
"Place was amazing and really helpful and nice staff"
The price is AED 694
AED 765 total
includes taxes & fees
24 Nov - 25 Nov
Legacy Resort Hotel & Spa
Alma San Diego Downtown, a Tribute Portfolio Hotel
4.0 star property
8.6 out of 10, Excellent, (326)
"Was a very nice stay. Room was clean, staff was friendly, pretty quiet."
The price is AED 414
AED 602 total
includes taxes & fees
22 Nov - 23 Nov
Alma San Diego Downtown, a Tribute Portfolio Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa.
THE US GRANT, a Luxury Collection Hotel, San Diego

THE US GRANT, a Luxury Collection Hotel, San Diego

326 Broadway, San Diego, CA
The price is AED 974 per night from Dec 10 to Dec 11
AED 974
AED 1,082 total
includes taxes & fees
10 Dec - 11 Dec
9/10 Wonderful! (998 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?
To book a 4-star hotel in Otay Mesa that fits your budget, take advantage of Expedia’s handy filters. Browse the availability during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most economical stay first.

  • Search for the lowest price from AED 974

What's the difference between 5-star and 4-star hotels in Otay Mesa?
Treat yourself to refined living during your Otay Mesa escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually filled with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more lavish and memorable one. Concierge assistance, elegant décor and world-class dining are a few of the exclusive conveniences and services you’ll likely be able to enjoy.
Does Otay Mesa have any 4-star all-inclusive resorts?
Finding your dream resort in Otay Mesa is as easy as typing in your travel details and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your accommodations, meals, activities and entertainment, or opt for a standard 4-star resort in or around this much-loved destination.