Find 4 Star Hotels in Otay Mesa, CA from AED 364

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Otay Mesa 4 Star Hotels

Tonight
26 Mar - 27 Mar
Tomorrow
27 Mar - 28 Mar
This weekend
28 Mar - 30 Mar
Next weekend
4 Apr - 6 Apr

Compare Otay Mesa 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham San Diego Bayside
Exterior

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very Good, (5694)
"Buen hotel, muy bien ubicado frente a bayside"
The price is AED 559
AED 630 total
includes taxes & fees
18 Apr - 19 Apr
Wyndham San Diego Bayside
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1017)
"It was a beautiful stay the pools were heated easy walk to the beach "
The price is AED 768
AED 1,020 total
includes taxes & fees
8 Apr - 9 Apr
Loews Coronado Bay Resort
San Diego Mission Bay Resort
Outdoor pool, open 9:00 AM to 9:00 PM, cabanas (surcharge)

San Diego Mission Bay Resort

4.0 star property
8.2 out of 10, Very Good, (1161)
"Great relaxing place to spend a weekend. "
The price is AED 694
AED 948 total
includes taxes & fees
2 Apr - 3 Apr
San Diego Mission Bay Resort
Legacy Resort Hotel & Spa
Lobby

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2875)
"Stay one night while shopping in San Diego. Conveniently located across Fashion Valley. The hotel is modern and clean with a good restaurant and day spa on site. Will consider staying again. "
The price is AED 731
AED 824 total
includes taxes & fees
30 Mar - 31 Mar
Legacy Resort Hotel & Spa
Sheraton San Diego Resort
View from room

Sheraton San Diego Resort

4.0 star property
8.0 out of 10, Very Good, (2595)
"Only place I would stay when in San Diego. "
The price is AED 558
AED 778 total
includes taxes & fees
20 Apr - 21 Apr
Sheraton San Diego Resort
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2649)
"Great location, exceptional Services! "
The price is AED 643
AED 890 total
includes taxes & fees
20 Apr - 21 Apr
Hard Rock Hotel San Diego
Hilton San Diego Mission Valley
Lobby

Hilton San Diego Mission Valley

4.0 star property
8.0 out of 10, Very Good, (1555)
"Loved everything about the stay "
The price is AED 459
AED 518 total
includes taxes & fees
13 Apr - 14 Apr
Hilton San Diego Mission Valley
Manchester Grand Hyatt San Diego
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2817)
"Close to Petco Park for events. Close for going anywhere in the Gaslamp area "
The price is AED 694
AED 957 total
includes taxes & fees
17 Apr - 18 Apr
Manchester Grand Hyatt San Diego
Lafayette Hotel & Club
Outdoor pool, open 7:00 AM to 9:00 PM, cabanas (surcharge)

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (694)
"Beautiful spot! Loved the decor and had a great vibe. Didn’t want to leave!"
The price is AED 757
AED 851 total
includes taxes & fees
27 Mar - 28 Mar
Lafayette Hotel & Club
The Little Italy Hotel Downtown San Diego
View from property

The Little Italy Hotel Downtown San Diego

4.0 star property
7.8 out of 10, Good, (1098)
"The night crew were especially awesome and very friendly."
The price is AED 496
AED 559 total
includes taxes & fees
20 Apr - 21 Apr
The Little Italy Hotel Downtown San Diego
Omni San Diego Hotel
Lobby sitting area

Omni San Diego Hotel

4.0 star property
9.0 out of 10, Wonderful, (1927)
"Great hotel with very friendly staff! "
The price is AED 732
AED 986 total
includes taxes & fees
18 Apr - 19 Apr
Omni San Diego Hotel
San Diego Marriott Gaslamp Quarter
Exterior

San Diego Marriott Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1359)
"Loved how close this was to Petco Park! There were many food and drink options available. Night life is fun and safe. "
The price is AED 528
AED 595 total
includes taxes & fees
17 Apr - 18 Apr
San Diego Marriott Gaslamp Quarter
Marriott Marquis San Diego Marina
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)

Marriott Marquis San Diego Marina

4.0 star property
9.0 out of 10, Wonderful, (1642)
"Nice gym and pool "
The price is AED 808
AED 1,041 total
includes taxes & fees
20 Apr - 21 Apr
Marriott Marquis San Diego Marina
Paradise Point Resort & Spa
Aerial view

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2121)
"Loved feeding the ducks!"
The price is AED 780
AED 1,061 total
includes taxes & fees
30 Mar - 31 Mar
Paradise Point Resort & Spa
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1197)
"Absolutely great location. Loved the rooftop and the on site restaurant. Right in the heart of the Gaslamp district. "
The price is AED 364
AED 513 total
includes taxes & fees
27 Mar - 28 Mar
Palihotel San Diego Gaslamp Quarter
Hotel del Coronado, Curio Collection by Hilton
Ice skating

Hotel del Coronado, Curio Collection by Hilton

4.0 star property
7.8 out of 10, Good, (1013)
"It’s always an amazing experience with The Hotel Del Coronado! We appreciate the staff and their commitment to making it awesome!"
The price is AED 1,769
AED 2,168 total
includes taxes & fees
23 Apr - 24 Apr
Hotel del Coronado, Curio Collection by Hilton
Hyatt Regency Mission Bay Spa and Marina
3 outdoor pools, cabanas (surcharge), pool umbrellas

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
8.6 out of 10, Excellent, (1468)
"Great interactions with staff and quick response when needed extra linens/pillows. Overall great location and stay "
The price is AED 657
AED 902 total
includes taxes & fees
27 Mar - 28 Mar
Hyatt Regency Mission Bay Spa and Marina
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Terrace/patio

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (798)
"Had an amazing trip with my wife. The room was very clean and comfortable. Staff were attentive and welcoming. We will definitely be back here. "
The price is AED 474
AED 534 total
includes taxes & fees
20 Apr - 21 Apr
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Sheraton Mission Valley San Diego Hotel
Outdoor pool

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.4 out of 10, Very Good, (1380)
"Very clean and the staff was very friendly"
The price is AED 433
AED 488 total
includes taxes & fees
31 Mar - 1 Apr
Sheraton Mission Valley San Diego Hotel
San Diego Marriott Mission Valley
Property amenity

San Diego Marriott Mission Valley

4.0 star property
8.6 out of 10, Excellent, (1018)
"Had a very smooth experience "
The price is AED 528
AED 595 total
includes taxes & fees
30 Mar - 31 Mar
San Diego Marriott Mission Valley
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa.
Pendry San Diego

Pendry San Diego

550 J Street, San Diego, CA
The price is AED 1,010 per night from Apr 10 to Apr 11
AED 1,010
AED 1,326 total
includes taxes & fees
10 Apr - 11 Apr
9.2/10 Wonderful! (1,003 reviews)
Still don't see what you're looking for?
See all properties in Otay Mesa.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?
To book a 4-star hotel in Otay Mesa that fits your budget, take advantage of Expedia’s handy filters. Browse the availability during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most economical stay first.

  • Search for the lowest price from AED 933

What's the difference between 5-star and 4-star hotels in Otay Mesa?
Treat yourself to refined living during your Otay Mesa escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually filled with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more lavish and memorable one. Concierge assistance, elegant décor and world-class dining are a few of the exclusive conveniences and services you’ll likely be able to enjoy.
Does Otay Mesa have any 4-star all-inclusive resorts?
Finding your dream resort in Otay Mesa is as easy as typing in your travel details and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your accommodations, meals, activities and entertainment, or opt for a standard 4-star resort in or around this much-loved destination.