Otay Mesa, CA

San Diego


Popular places to visit


Otay Mesa Hotel Deals

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is AED 388 per night from Apr 21 to Apr 22
AED 388
AED 437 total
includes taxes & fees
21 Apr - 22 Apr
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,470 reviews)
"This was a great property for location to the beach. A short 10 minute drive. There was also a shopping area just 5 minutes away with a ton of restaurants and a mall. The pool and hot tub were great, and pool was heated. The property was a little run down, but the staff did a great job keeping it ..."

Reviewed on 13 April 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is AED 621 per night from Apr 21 to Apr 22
AED 621
AED 700 total
includes taxes & fees
21 Apr - 22 Apr
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,667 reviews)
"Rooms were so nice and view was perfect! I will definitely stay here again!"

Reviewed on 15 April 2025

Wyndham San Diego Bayside
San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
The price is AED 694 per night from Apr 20 to Apr 21
AED 694
AED 948 total
includes taxes & fees
20 Apr - 21 Apr
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,174 reviews)
"First time in San Diego and this hotel was perfect. The room was spacious, parking was easy and lots to do on the property. The gym was good, the covewood restaurant on property was delicious! The nearby park was great with a really nice playground that our daughter enjoyed. My husband agrees this ..."

Reviewed on 15 April 2025

San Diego Mission Bay Resort
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is AED 621 per night from Apr 20 to Apr 21
AED 621
AED 700 total
includes taxes & fees
20 Apr - 21 Apr
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,314 reviews)
"A few insects in the bathroom in the morning"

Reviewed on 13 April 2025

The Dana on Mission Bay
Paradise Point Resort & Spa
Paradise Point Resort & Spa
4 out of 5
1404 Vacation Rd, San Diego, CA
The price is AED 780 per night from Apr 20 to Apr 21
AED 780
AED 1,061 total
includes taxes & fees
20 Apr - 21 Apr
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,138 reviews)
"Pretty grounds. Friendly staff"

Reviewed on 14 April 2025

Paradise Point Resort & Spa
Hilton San Diego Mission Valley
Hilton San Diego Mission Valley
4 out of 5
901 Camino Del Rio S, San Diego, CA
The price is AED 459 per night from Apr 21 to Apr 22
AED 459
AED 518 total
includes taxes & fees
21 Apr - 22 Apr
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
7.8/10 Good! (1,596 reviews)
"Great"

Reviewed on 14 April 2025

Hilton San Diego Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa

Petco Park featuring a statue or sculpture

East Village

Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.

East Village
Lake Murray in San Diego

Mid-City

If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Gaslamp Quarter
US Grant Hotel

Downtown San Diego

4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Downtown San Diego
Try the tamale eggs Benedict!

North Park

4/5(78 area reviews)

North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

North Park
Little Italy

Little Italy

Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.

Little Italy

Otay Mesa, CA

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