Otay Mesa, CA

San Diego


Popular places to visit


Otay Mesa Hotel Deals

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is AED 621 per night from Apr 20 to Apr 21
AED 621
AED 700 total
includes taxes & fees
20 Apr - 21 Apr
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,161 reviews)
"The hotel was nice but it was difficult to find any information. It’s the only hotel I’ve ever stayed in that didn’t offer a map of the property, a list of amenities with the times available (pool, etc.) or the dining options. It’s in a nice area that is convenient to public transportation."

Reviewed on 23 March 2025

The Dana on Mission Bay
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is AED 559 per night from Apr 18 to Apr 19
AED 559
AED 630 total
includes taxes & fees
18 Apr - 19 Apr
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,631 reviews)
"If you are taking a cruise this is the hotel for you. Any closer and you would be on the Pier! Friendly, efficient employees. Very satisfied with the room and the amenities. Will definitely return!"

Reviewed on 22 March 2025

Wyndham San Diego Bayside
San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
The price is AED 621 per night from Apr 21 to Apr 22
AED 621
AED 865 total
includes taxes & fees
21 Apr - 22 Apr
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,146 reviews)
"The service and Staff were excellent in providing information and follow-up. This may sound silly, but for someone like me with a bad back, the toilet bowl was far too low to the ground making it difficult to stand up."

Reviewed on 21 March 2025

San Diego Mission Bay Resort
Best Western Seven Seas
Best Western Seven Seas
3 out of 5
411 Hotel Circle South, San Diego, CA
The price is AED 334 per night from Mar 25 to Mar 26
AED 334
AED 376 total
includes taxes & fees
25 Mar - 26 Mar
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
7.6/10 Good! (2,658 reviews)
"I already did"

Reviewed on 22 March 2025

Best Western Seven Seas
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
The price is AED 413 per night from Apr 6 to Apr 7
AED 413
AED 465 total
includes taxes & fees
6 Apr - 7 Apr
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,794 reviews)
"Hotel was clean and well maintained. Only complaint is that although the breakfast food was good with warm full breakfast, the seating area is much too small for the hotel’s capacity."

Reviewed on 22 March 2025

Comfort Inn Sea World Area
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4 out of 5
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AED 731 per night from Mar 30 to Mar 31
AED 731
AED 824 total
includes taxes & fees
30 Mar - 31 Mar
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,858 reviews)
"I picked this place because it was central but also pretty new. It is well taken care of and the lobby is gorgeous."

Reviewed on 23 March 2025

Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa

Lake Murray in San Diego

Mid-City

If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Gaslamp Quarter
US Grant Hotel

Downtown San Diego

4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Downtown San Diego
Try the tamale eggs Benedict!

North Park

4/5(78 area reviews)

North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

North Park
Little Italy

Little Italy

Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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Del Cerro

3.5/5(122 area reviews)

Del Cerro might not have many top sights, but Cal Coast Credit Union Open Air Theater and Viejas Arena are two attractions nearby that you can check out.

Del Cerro

Otay Mesa, CA

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