Find Luxury Hotels in Otay Mesa, CA

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Check availability on Otay Mesa Luxury Hotels

Tonight
23 Feb - 24 Feb
Tomorrow
24 Feb - 25 Feb
Next weekend
28 Feb - 2 Mar
In two weeks
7 Mar - 9 Mar

Compare Otay Mesa Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites San Diego Otay Mesa
Exterior

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1002)
"Easy check in late at night"
The price is AED 385
AED 433 total
includes taxes & fees
23 Mar - 24 Mar
Quality Suites San Diego Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Otay Mesa?
Use Expedia to arrange your flight to Tijuana Intl. Airport (TIJ) airport or San Diego Intl. Airport (SAN) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to get what you want to make your stay special. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Otay Mesa has to offer. During your visit, you might want to enjoy the restaurants which Otay Mesa is known for.
What's the best time to vacation in Otay Mesa?
The hottest months are usually August and September with an average temperature of 71°F,
  • Coldest months: February, January, December, and March
  • Driest months: June, July, September, and August
  • Rainiest months: December, February, January, and March
What's there to see and do in Otay Mesa?
Enjoy Otay Mesa and visit San Ysidro Border Crossing, San Diego Zoo, and Petco Park. If you have a bit of extra time while you’re in the area, you might want to check out Balboa Park and USS Midway Museum.