Find Resorts & Hotels with Spas in Otay Mesa, CA

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Check availability on Otay Mesa Resorts & Hotels with Spas

Tonight
28 Feb - 1 Mar
Tomorrow
1 Mar - 2 Mar
This weekend
28 Feb - 2 Mar
Next weekend
7 Mar - 9 Mar

Compare Otay Mesa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites San Diego Otay Mesa
Outdoor pool

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1001)
"Easy check in late at night"
The price is AED 385
AED 433 total
includes taxes & fees
23 Mar - 24 Mar
Quality Suites San Diego Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Otay Mesa?
Treat yourself to some pampering and book a hotel with a spa. Check out the theater scene and shopping in Otay Mesa—your day trip starts here. Discover the beaches and many popular restaurants during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your holiday.
How many spa hotels will I find in Otay Mesa?
Among Expedia’s 3 accommodation options in Otay Mesa, there are 2 spa hotels.
What's there to see and do in Otay Mesa?
Enjoy Otay Mesa with a stop at San Ysidro Border Crossing, San Diego Zoo, and Petco Park. If you have spare time during your trip, you might want to make a stop at Balboa Park and USS Midway Museum.
What is a Otay Mesa spa hotel?
Spa hotels in Otay Mesa provide lodging and have a full on-site spa which offers services like massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.