Find Resorts & Hotels with Spas in Otay Mesa, CA

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Check availability on Otay Mesa Resorts & Hotels with Spas

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Compare Otay Mesa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (998)
"location was ok. location is close to cbx"
The price is AED 375
AED 426 total
includes taxes & fees
11 May - 12 May
Quality Suites San Diego Otay Mesa

Modern 3-bedroom SD Townhome with WiFi, Office, AC, EV Charger, Garage & More

Modern 3-bedroom SD Townhome with WiFi, Office, AC, EV Charger, Garage & More
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Otay Mesa?
Treat yourself to some pampering and book a hotel with a spa. Check out the theater scene and shopping in Otay Mesa—your day trip starts here. Discover the beaches and many popular restaurants during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your holiday.
How many spa hotels will I find in Otay Mesa?
Among Expedia’s 3 accommodation options in Otay Mesa, there are 2 spa hotels.
What's there to see and do in Otay Mesa?
Enjoy Otay Mesa with a stop at San Diego Zoo, San Ysidro Border Crossing, and Petco Park. If you have spare time during your trip, you might want to make a stop at Coronado Beach and Rosarito Beach.
What is a Otay Mesa spa hotel?
Spa hotels in Otay Mesa provide lodging and have a full on-site spa which offers services like massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.