Photo by Ronald Wilson

Find Luxury Hotels in Lake City, FL

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Lake City Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Palms Garden Inn
Property entrance

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (511)
"Property was clean and convenient to highway and quick dining, room was a bit musty but well kept"
The price is AED 246
AED 277 total
includes taxes & fees
29 Dec - 30 Dec
Palms Garden Inn
Americas Best Value Inn Lake City
Exterior

Americas Best Value Inn Lake City

2.0 star property
8.6 out of 10, Excellent, (1003)
"The room was very clean"
The price is AED 262
AED 295 total
includes taxes & fees
1 Jan - 2 January 2025
Americas Best Value Inn Lake City
Driftwood Inn
Exterior

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (724)
"Doesn’t look like much from the street, but the rooms were very nice. Obviously the bath room fixtures weren’t new, but no complaints. Very easy parking at the door. Be aware there is no breakfast, but that is reflected in the price. Lots of dining options close by. Walmart is right across the street. Room had refrigerator and microwave. I would return. "
The price is AED 360
AED 405 total
includes taxes & fees
23 Dec - 24 Dec
Driftwood Inn
Econo Lodge Lake City-North
Exterior

Econo Lodge Lake City-North

2.0 star property
6.8 out of 10, (372)
"N/a"
The price is AED 274
AED 309 total
includes taxes & fees
2 Jan - 3 January 2025
Econo Lodge Lake City-North
Comfort Suites Lake City
Exterior

Comfort Suites Lake City

2.5 star property
9.6 out of 10, Exceptional, (1004)
"Excellent location . Very convenient to I 75 "
The price is AED 428
AED 482 total
includes taxes & fees
5 Jan - 6 January 2025
Comfort Suites Lake City
Days Inn by Wyndham Lake City I-10
Lobby

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1002)
"We needed a stop over during a long trip to see family. This was along the way and was a good stop-over place for the night."
The price is AED 297
AED 334 total
includes taxes & fees
25 Dec - 26 Dec
Days Inn by Wyndham Lake City I-10
Super 8 by Wyndham Lake City
Pool

Super 8 by Wyndham Lake City

2.0 star property
7.0 out of 10, Good, (585)
"Sharon the manager does an excellent job of taking care of facililties."
The price is AED 474
AED 533 total
includes taxes & fees
16 Jan - 17 January 2025
Super 8 by Wyndham Lake City
Rodeway Inn Lake City I-75
Exterior

Rodeway Inn Lake City I-75

2.0 star property
6.8 out of 10, (353)
"The manager came to my room and helped program the remote for the TV....he was so kind and fun!"
The price is AED 231
AED 260 total
includes taxes & fees
29 Dec - 30 Dec
Rodeway Inn Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Lake City

Frequently asked questions

Are you looking for a luxury hotel for your stay in Lake City?
Use Expedia to arrange your flight to Gainesville Regional Airport (GNV) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Lake City has to offer. While you’re visiting, you might want to think about enjoying the festivals and sporting events, which Lake City is known for.
How many luxury hotels will I find in Lake City?
Lie in the lap of luxury during your getaway to Lake City in one of Expedia’s 12 luxury hotels.
When can I expect good weather in Lake City?
Planning for the weather is an important factor for making your trip to Lake City a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Lake City is 51 inches.
What's there to see and do in Lake City?
When you’re in Lake City, enjoy exploring the sights and attractions here including Florida Department of Transportation, Southside Sports Complex, and Lake City Mall. If you have spare time during your trip, you might want to make a stop at North Florida Speedway and O’Leno State Park.