Photo by Ronald Wilson

Find Luxury Hotels in Lake City, FL

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Check availability on Lake City Luxury Hotels

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Compare Lake City Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (528)
"Family owned and operated. Plenty if great lighting and brand new state of the art security cameras. 2 huge truckstops close by, Subway, Dunkin' etc Hotel currently undergoing remodel/refresh. Staff is super friendly and accommodating. Rates are great. I"ve stayed here several times and will continue to stay inbthe future. Also goid wifi and satellite tv with lot's of channels :-)"
The price is AED 246
AED 277 total
includes taxes & fees
2 Apr - 3 Apr
Palms Garden Inn

Americas Best Value Inn Lake City

2.0 star property
8.8 out of 10, Excellent, (1034)
"Super friendly staff"
The price is AED 278
AED 312 total
includes taxes & fees
6 Apr - 7 Apr
Americas Best Value Inn Lake City

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (727)
"This was a bare bones hotel. The room was clean and the beds were comfortable. There was Wi-Fi and a tv, and not much else. If all you want is a comfortable bed, then this is the place for you. "
The price is AED 264
AED 298 total
includes taxes & fees
2 Apr - 3 Apr
Driftwood Inn

Econo Lodge Lake City-North

2.0 star property
6.8 out of 10, (386)
"Great staff"
The price is AED 274
AED 309 total
includes taxes & fees
2 Apr - 3 Apr
Econo Lodge Lake City-North

Comfort Suites Lake City

2.5 star property
9.6 out of 10, Exceptional, (1010)
"This hotel is hands down the best in Lake City!"
The price is AED 395
AED 444 total
includes taxes & fees
20 Apr - 21 Apr
Comfort Suites Lake City

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1051)
"Clean, well priced, close to interstate "
The price is AED 265
AED 299 total
includes taxes & fees
30 Mar - 31 Mar
Days Inn by Wyndham Lake City I-10

Super 8 by Wyndham Lake City

2.0 star property
7.0 out of 10, Good, (598)
"It was a good place to stay it was clean and quiet. I’d stay there again."
The price is AED 324
AED 364 total
includes taxes & fees
30 Mar - 31 Mar
Super 8 by Wyndham Lake City

Rodeway Inn Lake City I-75

2.0 star property
6.6 out of 10, (370)
"quite "
The price is AED 248
AED 279 total
includes taxes & fees
9 Apr - 10 Apr
Rodeway Inn Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in Lake City?
Use Expedia to arrange your flight to Gainesville Regional Airport (GNV) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Lake City has to offer. While you’re visiting, you might want to think about enjoying the festivals and sporting events, which Lake City is known for.
How many luxury hotels will I find in Lake City?
Lie in the lap of luxury during your getaway to Lake City in one of Expedia’s 12 luxury hotels.
When can I expect good weather in Lake City?
Planning for the weather is an important factor for making your trip to Lake City a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Lake City is 51 inches.
What's there to see and do in Lake City?
When you’re in Lake City, enjoy exploring the sights and attractions here including Columbia County Courthouse, Florida Department of Transportation, and Southside Recreation Complex. If you have spare time during your trip, you might want to make a stop at Southside Sports Complex and Lake City Mall.