Find Resorts & Hotels with Spas in St. Louis, MO

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Pick from 33 St. Louis Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Four Seasons Hotel St Louis
Terrace/patio

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (968)
"Wonderful stay! Thank you!"
The price is AED 1,377
AED 1,611 total
includes taxes & fees
3 Jan - 4 January 2025
Four Seasons Hotel St Louis
Embassy Suites by Hilton St. Louis St. Charles
Exterior

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1158)
"Check in was quick and easy. Our room was very comfortable and clean. "
The price is AED 438
AED 503 total
includes taxes & fees
29 Dec - 30 Dec
Embassy Suites by Hilton St. Louis St. Charles
Drury Plaza Hotel St. Louis at the Arch
Exterior

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (2338)
"Hotel was perfect for our weekend in St. Louis. Walking distance to the arch and a short Uber ride to the Blues game."
The price is AED 463
AED 541 total
includes taxes & fees
22 Dec - 23 Dec
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch
Exterior

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (3534)
"It was a perfect stay! The valet and concierge was great! Also had amazing dinner at Ruth's Criss Steakhouse which is located inside the hotel. Only issue was only 2 of the elevators were working. Was a wonderful stay and will definitely stay again."
The price is AED 340
AED 392 total
includes taxes & fees
1 Jan - 2 January 2025
Hyatt Regency St. Louis at The Arch
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Exterior

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3.0 star property
9.0 out of 10, Wonderful, (799)
"It was fine. Served its purpose. The breakfast was ok. Could have used some fruit or healthier items. And would like to have housekeeping services daily. "
The price is AED 465
AED 537 total
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Drury Inn & Suites St. Louis Arnold
Exterior

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1000)
"Always enjoy Drury Inn. This one is close to family and the breakfast and happy hour deal is amazing. Appreciate the very friendly staff as well. Feels like staying with friends!"
The price is AED 413
AED 478 total
includes taxes & fees
22 Dec - 23 Dec
Drury Inn & Suites St. Louis Arnold
Homewood Suites by Hilton St. Louis Riverport - Airport West
Exterior

Homewood Suites by Hilton St. Louis Riverport - Airport West

3.0 star property
7.4 out of 10, Good, (1003)
"Rooms was spacious "
The price is AED 300
AED 348 total
includes taxes & fees
29 Dec - 30 Dec
Homewood Suites by Hilton St. Louis Riverport - Airport West
Drury Inn & Suites St. Louis Brentwood
Pool

Drury Inn & Suites St. Louis Brentwood

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Very clean and friendly staff."
The price is AED 441
AED 524 total
includes taxes & fees
22 Dec - 23 Dec
Drury Inn & Suites St. Louis Brentwood
Drury Inn & Suites St. Louis Airport
Exterior

Drury Inn & Suites St. Louis Airport

3.0 star property
9.2 out of 10, Wonderful, (1002)
"Felt very safe as a solo traveler. Easy parking and very close to airport! Will definitely stay again when flying out of STL!"
The price is AED 397
AED 465 total
includes taxes & fees
22 Dec - 23 Dec
Drury Inn & Suites St. Louis Airport
Pear Tree Inn St. Louis Convention Center
Exterior

Pear Tree Inn St. Louis Convention Center

3.0 star property
8.8 out of 10, Excellent, (1001)
"👍"
The price is AED 364
AED 425 total
includes taxes & fees
22 Dec - 23 Dec
Pear Tree Inn St. Louis Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers love the fascinating museums and live music scene in St. Louis so get ready for a cultural tour. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in St. Louis?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, and a 24-hour fitness center. Treat yourself to a facial, body scrub, or hydrotherapy at Ara. Other popular spa hotels in St. Louis include Four Seasons Hotel St Louis and Hotel Saint Louis, Autograph Collection.
How many spa hotels will I find in St. Louis?
Among Expedia’s 1903 accommodation options in St. Louis, there are 3 spa hotels.
What's there to see and do in St. Louis?
Experience St. Louis and visit St. Louis Union Station, St. Louis Aquarium at Union Station, and Enterprise Center. If you have spare time during your trip, you might want to make a stop at Peabody Opera House and Washington Avenue Historic District.
What is a St. Louis spa hotel?
Spa hotels in St. Louis provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.