Find Resorts & Hotels with Spas in San Luis Obispo, CA

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Check availability on San Luis Obispo Resorts & Hotels with Spas

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Compare San Luis Obispo Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites Downtown San Luis Obispo

3.0 star property
9.4 out of 10, Exceptional, (1069)
"Wonderful location and staff"
The price is AED 459
AED 596 total
includes taxes & fees
26 May - 27 May
Quality Suites Downtown San Luis Obispo

Hotel San Luis Obispo

4.5 star property
9.6 out of 10, Exceptional, (486)
"Beautiful property Rooms are spacious Excellent food options and location "
The price is AED 1,484
AED 1,685 total
includes taxes & fees
5 May - 6 May
Hotel San Luis Obispo

University Inn

2.0 star property
8.0 out of 10, Very Good, (1001)
"Great location. "
University Inn

Madonna Inn

3.5 star property
9.2 out of 10, Wonderful, (1168)
"Great property, great room, pool, bar and restraurant"
The price is AED 768
AED 997 total
includes taxes & fees
11 May - 12 May
Madonna Inn

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1458)
"Nice place to stay in SLO, walking distance to restaurants a big plus. "
The price is AED 506
AED 575 total
includes taxes & fees
26 May - 27 May
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

Vagabond Inn San Luis Obispo

2.0 star property
8.4 out of 10, Very Good, (1081)
"Cheap & easy place to stay."
The price is AED 235
AED 311 total
includes taxes & fees
18 May - 19 May
Vagabond Inn San Luis Obispo

Mission Inn San Luis Obispo

2.0 star property
7.8 out of 10, Good, (792)
"Great area! Nice rooms and close to dinning areas."
The price is AED 215
AED 286 total
includes taxes & fees
20 May - 21 May
Mission Inn San Luis Obispo

HOTEL CERRO, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (443)
"Hotel CERRO is a beautiful boutique hotel. The suites are lovely. Perfect location!"
The price is AED 1,219
AED 1,497 total
includes taxes & fees
11 May - 12 May
HOTEL CERRO, Autograph Collection

Motel 6 San Luis Obispo, CA - South

2.0 star property
8.2 out of 10, Very Good, (1013)
"good place to stay"
The price is AED 331
AED 376 total
includes taxes & fees
11 May - 12 May
Motel 6 San Luis Obispo, CA - South

Best Western Plus Royal Oak Hotel

2.5 star property
8.6 out of 10, Excellent, (1002)
"Nice next door too Madonna Inn"
The price is AED 454
AED 517 total
includes taxes & fees
11 May - 12 May
Best Western Plus Royal Oak Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your vacation. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness center, tennis courts, a bar, and an outdoor pool. Spend an afternoon at The Spa at Madonna Inn. where you’ll find facials, body scrubs, and Swedish massages and more. Other popular spa hotels in San Luis Obispo include Hotel San Luis Obispo and HOTEL CERRO, Autograph Collection.
How many spa hotels will I find in San Luis Obispo?
Among Expedia’s 207 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers’ Market, and San Luis Obispo Superior Court. If you have extra time while you’re in the area, you might want to see Mission San Luis Obispo de Tolosa and Ah Louis Store.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.