Find Resorts & Hotels with Spas in San Luis Obispo, CA

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Pick from 15 San Luis Obispo Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites Downtown San Luis Obispo
3.0 star property
9.4 out of 10, Exceptional, (1016)
"I was pleased with the size of the suite; there were two rooms, each had a tv, The bed was fine but there was just one large comforter and no sheets, it wasn’t ideal for hot sleepers like me. I was surprised to find hair on the ground in the bathroom. Not really sure how housekeeping missed that as it was dark and course. Except for finding hair on the bathroom floor, the stay was near to exceptional. I would like to get a bigger waffle with breakfast (size of a small burger)."
The price is AED 350
AED 464 total
includes taxes & fees
17 Nov 2024 - 18 Nov 2024
Quality Suites Downtown San Luis Obispo
Hotel San Luis Obispo
4.5 star property
9.4 out of 10, Exceptional, (434)
"The room was spacious, and comfortable. The staff are SO friendly and helpful. We really loved the rooftop bar and the pizza and wine on Monday night were delicious! Also, we love the location. We walked everywhere. Made too many trips to Boo Boo Records! A big favorite! Can’t wait to come back. "
The price is AED 1,220
AED 1,384 total
includes taxes & fees
21 Nov 2024 - 22 Nov 2024
Hotel San Luis Obispo
University Inn
2.0 star property
8.2 out of 10, Very Good, (963)
"Everything was as expected "
University Inn
Madonna Inn
3.5 star property
9.2 out of 10, Wonderful, (1085)
"Property is a unique gem offering a wide variety of experiences. Hourly staff seemed to be engaged and desirous of being helpful. However, all of the management encountered were the opposite and indifferent if not rude. After having spent a significant portion of money for a three days day one would have imagined that in departing the desk attendant/manager would have at least asked if this stay was enjoyable and thanked me for our patronage; honestly, based off of my experience with that one...
The price is AED 451
AED 625 total
includes taxes & fees
4 Nov 2024 - 5 Nov 2024
Madonna Inn
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
3.0 star property
9.0 out of 10, Wonderful, (1319)
"Great place to stay in San Luis Obispo. Good location and a reasonable price. I recommend that place "
The price is AED 384
AED 436 total
includes taxes & fees
18 Nov 2024 - 19 Nov 2024
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Vagabond Inn San Luis Obispo
2.0 star property
8.4 out of 10, Very Good, (1040)
"Excellent room! The pool and spa were lovely as well. "
The price is AED 239
AED 315 total
includes taxes & fees
11 Nov 2024 - 12 Nov 2024
Vagabond Inn San Luis Obispo
Mission Inn San Luis Obispo
2.0 star property
7.6 out of 10, Good, (764)
"Very clean room , pet friendly. I would highly reccomend it and will gladly stay again. "
The price is AED 232
AED 305 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
Mission Inn San Luis Obispo
HOTEL CERRO, Autograph Collection
4.0 star property
9.2 out of 10, Wonderful, (419)
"This was an ideal location for everything downtown. It was our central spot when visiting surrounding areas. The only let down was leaving two pieces of clothing behind and the housekeeping unable to locate them. That was a little disheartening seeing that I called as soon as I realized. "
The price is AED 757
AED 958 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
HOTEL CERRO, Autograph Collection
Motel 6 San Luis Obispo, CA - South
2.0 star property
8.2 out of 10, Very Good, (1010)
"It was just what I wanted a comfortable place to sleep. "
The price is AED 294
AED 328 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Motel 6 San Luis Obispo, CA - South
Best Western Plus Royal Oak Hotel
2.5 star property
8.6 out of 10, Excellent, (1005)
"Thank Rosa was great customer service "
The price is AED 487
AED 544 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
Best Western Plus Royal Oak Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your vacation. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness center, tennis courts, a bar, and an outdoor pool. Spend an afternoon at The Spa at Madonna Inn. where you’ll find facials, body scrubs, and Swedish massages and more. Other popular spa hotels in San Luis Obispo include HOTEL CERRO, Autograph Collection and Hotel San Luis Obispo.
How many spa hotels will I find in San Luis Obispo?
Among Expedia’s 214 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers’ Market, and San Luis Obispo Superior Court. If you have extra time while you’re in the area, you might want to see Bubblegum Alley and Mission San Luis Obispo de Tolosa.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.