Find Resorts & Hotels with Spas in San Luis Obispo, CA

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on San Luis Obispo Resorts & Hotels with Spas

Tonight
5 Apr - 6 Apr
Tomorrow
6 Apr - 7 Apr
Next weekend
11 Apr - 13 Apr
In two weeks
18 Apr - 20 Apr

Compare San Luis Obispo Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites Downtown San Luis Obispo
Lobby

Quality Suites Downtown San Luis Obispo

3.0 star property
9.4 out of 10, Exceptional, (1043)
"Not new, but renovated and updated. "
The price is AED 493
AED 633 total
includes taxes & fees
20 Apr - 21 Apr
Quality Suites Downtown San Luis Obispo
Hotel San Luis Obispo
Morro Suite | Living area | 55-inch flat-screen TV with cable channels, TV

Hotel San Luis Obispo

4.5 star property
9.6 out of 10, Exceptional, (482)
"I f-ing love this hotel. I’ve stayed at very nice hotels all over, but this may actually be my favorite. "
The price is AED 1,583
AED 1,797 total
includes taxes & fees
6 Apr - 7 Apr
Hotel San Luis Obispo
University Inn
Desk, laptop workspace, free WiFi, bed sheets

University Inn

2.0 star property
8.0 out of 10, Very Good, (1003)
"This was great for our needs. We were there to see University Cal Poly events for a grandchild, as were most of the other occupants it seemed. It worked our perfect. "
The price is AED 1,117
AED 1,372 total
includes taxes & fees
11 Apr - 12 Apr
University Inn
Madonna Inn
Outdoor pool, pool umbrellas

Madonna Inn

3.5 star property
9.2 out of 10, Wonderful, (1156)
"Great customer service"
The price is AED 787
AED 1,018 total
includes taxes & fees
6 Apr - 7 Apr
Madonna Inn
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Outdoor pool, open 10:00 AM to 10:00 PM, sun loungers

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1435)
"Close to University and downtown with great full breakfast."
The price is AED 461
AED 524 total
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Vagabond Inn San Luis Obispo
Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers

Vagabond Inn San Luis Obispo

2.0 star property
8.4 out of 10, Very Good, (1070)
"Pet friendly "
The price is AED 217
AED 291 total
includes taxes & fees
6 Apr - 7 Apr
Vagabond Inn San Luis Obispo
Mission Inn San Luis Obispo
Property entrance

Mission Inn San Luis Obispo

2.0 star property
7.8 out of 10, Good, (789)
"TV didn't work. One station, CRICKET. Tried to call front desk a few times, no answer. Room clean, slept well."
The price is AED 253
AED 329 total
includes taxes & fees
14 Apr - 15 Apr
Mission Inn San Luis Obispo
HOTEL CERRO, Autograph Collection
Sundeck

HOTEL CERRO, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (442)
"Great hotel ! Perfect location "
The price is AED 988
AED 1,234 total
includes taxes & fees
13 Apr - 14 Apr
HOTEL CERRO, Autograph Collection
Motel 6 San Luis Obispo, CA - South
Desk, free WiFi, bed sheets

Motel 6 San Luis Obispo, CA - South

2.0 star property
8.2 out of 10, Very Good, (1002)
"t"
The price is AED 331
AED 376 total
includes taxes & fees
13 Apr - 14 Apr
Motel 6 San Luis Obispo, CA - South
Best Western Plus Royal Oak Hotel
Outdoor pool, a heated pool, pool umbrellas, sun loungers

Best Western Plus Royal Oak Hotel

2.5 star property
8.6 out of 10, Excellent, (1003)
"We enjoyed this hotel. Very clean and friendly staff. They have a pet area which we enjoyed with our dog. Nice hot breakfast every morning. We will definitely stay here again."
The price is AED 474
AED 539 total
includes taxes & fees
6 Apr - 7 Apr
Best Western Plus Royal Oak Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in San Luis Obispo

Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your vacation. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness center, tennis courts, a bar, and an outdoor pool. Spend an afternoon at The Spa at Madonna Inn. where you’ll find facials, body scrubs, and Swedish massages and more. Other popular spa hotels in San Luis Obispo include HOTEL CERRO, Autograph Collection and Hotel San Luis Obispo.
How many spa hotels will I find in San Luis Obispo?
Among Expedia’s 202 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers’ Market, and San Luis Obispo Superior Court. If you have extra time while you’re in the area, you might want to see Mission San Luis Obispo de Tolosa and Performing Arts Center.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.