Find Beach Hotels in Panacea, FL

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Pick from 129 Panacea Beach Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Oceanfront Retro Beach Home on the Gulf! Gorgeous views! - FALL SPECIAL 25% OFF
Interior
Oceanfront Retro Beach Home on the Gulf! Gorgeous views! - FALL SPECIAL 25% OFF
9.4 out of 10, Exceptional, (19)
"Andrea was very responsive. What a wonderful remote area. So peaceful and relaxing. "
Oceanfront Retro Beach Home on the Gulf! Gorgeous views! - FALL SPECIAL 25% OFF
Secluded Florida Beach Bungalow 20% OFF FALL SPECIAL!!
The beach to enjoy at The Spotted Grouper.
Secluded Florida Beach Bungalow 20% OFF FALL SPECIAL!!
10.0 out of 10, Exceptional, (230)
"Clean, cute, and close to the beach! Good restaurants if you don’t want to cook. Enough space for all of us and a tv in every room which we hardly turned on until nighttime. Would reccomend"
Secluded Florida Beach Bungalow 20% OFF FALL SPECIAL!!
Coastal Getaway on canal-steps to the beach
Exterior
Coastal Getaway on canal-steps to the beach
10.0 out of 10, Exceptional, (43)
"The place was cozy and comfortable. It is must bigger than the pictures show. Outdoor shower area is awesome to clean up after fishing or day at the beach."
Coastal Getaway on canal-steps to the beach
Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!
Exterior
Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!
9.8 out of 10, Exceptional, (103)
"50 steps to the beach (we measured), beautiful Gulf of Mexico, and all the house accommodations we could ask for at this price. What else you should know... The closest small food store is 5 miles away. The beach sand is gorgeous. The water is a bit stained due to the nearby Ochlockonee River (might vary with the tide.)"
Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!
PRIVATE LUXURY BEACHFRONT HOME! - WINTER DISCOUNTS!
Living area
PRIVATE LUXURY BEACHFRONT HOME! - WINTER DISCOUNTS!
10.0 out of 10, Exceptional, (89)
"We’ve stayed in Alligator Point this time of year many times over the last 20 yrs. Our needs and groups have changed too so this location fit our needs perfectly. Each group had their own bedroom and bathroom. The kitchen was beautiful and well stocked. Will definitely be back."
PRIVATE LUXURY BEACHFRONT HOME! - WINTER DISCOUNTS!
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Pool
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
10.0 out of 10, Exceptional, (111)
"We loved the house! Perfect for a large family. The owners have though of everything from pool floats to beach chairs to a crock pot! The pool is an added bonus and the close walk to the Tiki Hut makes for a fun afternoon. Loved our stay. "
The price is AED 3,306
AED 7,184 total
includes taxes & fees
23 Nov - 24 Nov
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Hideaway Beach Cottage on waterfront with amazing views.
Dining
Hideaway Beach Cottage on waterfront with amazing views.
10.0 out of 10, Exceptional, (29)
"Thoroughly enjoyed our stay, wonderful porch with large yard right on the bay. Nice great room with amazing ranch style table with benches."
Hideaway Beach Cottage on waterfront with amazing views.
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
Exterior
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
10.0 out of 10, Exceptional, (57)
"The house and property are both well kept , not to mention gorgeous too. Steps from a great fishing babyfishing beach"
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
Marsh Beauty
Living area
Marsh Beauty
9.8 out of 10, Exceptional, (35)
"Love the property and the host was super accommodating. We are planning on going back."
Marsh Beauty
CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom
Boat slip usage for an additional fee.
CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom
9.4 out of 10, Exceptional, (87)
"We loved staying here! Place is very clean, beds are comfortable and host was very accommodating. My son was able to walk outside and fish. We walked to Angelo’s for dinner and the beach is very close. We will be staying here again :)"
CONDO Water front, bay breeze, fishing paradise and family friendly 2 bedroom
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is Panacea like for travelers who love the beach?
Known for its beaches and fishing, Panacea has a lot to offer the traveler dreaming of a beach holiday.
How many beach hotels can I expect to find in Panacea?
Choose from one of Expedia’s 25 hotels in Panacea for your beachside break.
When's the best time for a beach vacation in Panacea?
Plan your trip to the beach with this snapshot of year-round temperatures in Panacea: The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.
What is there to see and do around Panacea?
After arriving and checking into your hotel, you’ll probably want to explore your surroundings. If you can’t wait to check out the beaches, head to Wilson Beach or Shell Point Beach for a relaxing day by the water. Discover the area’s fresh seafood and fishing, and make time for local attractions like Mashes Sand Beach and Alligator Point Beach. For even more to see and do, pay a visit to Bald Point State Park or USS Mohawk CGC Veterans Memorial Reef.
What's the best way to get to my beach hotel in Panacea?
Here’s some information to help you get to and around your beach accommodation in Panacea with ease. To get to Panacea, you can fly into Tallahassee Intl. Airport (TLH), the closest major airport, which is located 25.5 mi (41.1 km) from the city center. If you’d like to venture out around the area, you may want a rental car for your journey.