Find hotels in Santo Spirito, Florence from AED 342

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 455 Santo Spirito hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Fonderia Firenze

9.6 out of 10, Exceptional, (151)
"Quiet and cozy. Friendly staff, safe location and a beautiful property. "
The price is AED 608
AED 719 total
includes taxes & fees
28 May - 29 May
La Fonderia Firenze

Foresteria Valdese di Firenze - Casa per Ferie

8.8 out of 10, Excellent, (130)
"Excellent location, close to main plaza "
Foresteria Valdese di Firenze - Casa per Ferie

UNA HOTELS Vittoria Firenze

4.0 star property
8.4 out of 10, Very Good, (1000)
"."
The price is AED 550
AED 662 total
includes taxes & fees
25 May - 26 May
UNA HOTELS Vittoria Firenze

Palazzo Oliveto

7.8 out of 10, Good, (66)
"Great place for the value "
The price is AED 342
AED 426 total
includes taxes & fees
18 May - 19 May
Palazzo Oliveto

Hotel Firenze 2000

2.0 star property
7.2 out of 10, Good, (159)
"very happy with our hotel"
The price is AED 607
AED 705 total
includes taxes & fees
21 May - 22 May
Hotel Firenze 2000

Soderini Apartments by MMega

10.0 out of 10, Exceptional, (2)
The price is AED 352
AED 1,094 total
includes taxes & fees
18 May - 19 May
Soderini Apartments by MMega

La Torre Del Cestello

9.0 out of 10, Wonderful, (179)
"Loved our stay! Great area"
The price is AED 645
AED 758 total
includes taxes & fees
27 May - 28 May
La Torre Del Cestello

Casa Santo Nome di Gesù

8.6 out of 10, Excellent, (281)
"Beautifully kept, clean, helpful and welcoming staff. The Garden is lovely, breakfast well done, and neighborhood easily accessible."
The price is AED 636
AED 749 total
includes taxes & fees
18 May - 19 May
Casa Santo Nome di Gesù

Torre di Bellosguardo

4.0 star property
9.0 out of 10, Wonderful, (92)
"Beautiful property and wonderful staff."
The price is AED 1,938
AED 2,189 total
includes taxes & fees
17 May - 18 May
Torre di Bellosguardo

Home in Florence

8.8 out of 10, Excellent, (68)
"Perfect place, super friendly owners, really helpful. "
The price is AED 451
AED 545 total
includes taxes & fees
20 May - 21 May
Home in Florence

Camaldoli 8 Apartment

The price is AED 364
AED 834 total
includes taxes & fees
21 May - 22 May
Camaldoli 8 Apartment

Art Gallery Apartment in Florence

7.0 out of 10, Good, (2)
"I was asked what time I would like to check in, I requested 2pm the reply said I suggested 4pm! I asked to leave luggage at 1pm but no one got there until 2 and said check in is at 3 but they’re running late. Expedia has 2pm check in. They charge early check in fees but you don’t get anything if they’re late! I sat there over an hour and still no cleaners. I was told 2 of them would do the job so it’s quicker. There was only one guy! Apt. was rushed cleaned in about 1 hour and ready at 5:30....
The price is AED 530
AED 1,605 total
includes taxes & fees
17 May - 18 May
Art Gallery Apartment in Florence

Hotel Horto Convento

4.0 star property
9.8 out of 10, Exceptional, (510)
"beautiful, historic and quiet sophistication - enjoyed our stay!"
The price is AED 884
AED 1,030 total
includes taxes & fees
2 Jun - 3 Jun
Hotel Horto Convento

Appartamenti degli Artisti by Mmega

9.2 out of 10, Wonderful, (9)
"The apartment is in a good location and very clean."
The price is AED 523
AED 953 total
includes taxes & fees
22 May - 23 May
Appartamenti degli Artisti by Mmega

Drom Florence Rooms & Apartments

9.8 out of 10, Exceptional, (119)
"This was an excellent property to stay at. The owner was so welcoming and friendly. I enjoyed the quietness of the neighborhood and how close it was to things!"
The price is AED 699
AED 819 total
includes taxes & fees
18 May - 19 May
Drom Florence Rooms & Apartments

Torrigiani View by Mmega

9.0 out of 10, Wonderful, (2)
"Light and airy. Great location if you’re looking to stay in a family friendly neighborhood. Not too far to walk to the city center of Florence. Grocery store just around the corner was very convenient. There’s a lovely park across the street. We loved it! "
The price is AED 418
AED 879 total
includes taxes & fees
19 May - 20 May
Torrigiani View by Mmega

Mamo Florence - Maddalena Apartment

10.0 out of 10, Exceptional, (1)
"Fantastic top floor apartment in medieval building just beyond the Palazzo Pitti on the quieter side of the Arno. There's a cafe and a supermarket nearby, a very popular pizzeria and Santo Spirito 5 minutes away and the heart of the city is just 10 to 15 minutes walk away. The apartment had everything we needed for a family of 5, great cooking facilities and a neat and tidy bathroom. We'd definitely stay there again if we return to Florence. "
The price is AED 638
AED 1,101 total
includes taxes & fees
2 Jun - 3 Jun
Mamo Florence - Maddalena Apartment

B&B Mia Palace

8.2 out of 10, Very Good, (104)
"This property was exceptionally clean. The only thing we are complaining about is that the window to the street doesn’t close completely so we can hear the noise from the street. It was quiet at night because there was not cars driving, otherwise there was noise. One of the greatest things we loved was the breakfast. There are no places in Florence that give breakfast for free like Mia’s place. And breakfast was amazing. Nadia is a wonderful hosts. Everything is within walking distance (10...
The price is AED 481
AED 578 total
includes taxes & fees
18 May - 19 May
B&B Mia Palace

Mamo Florence - Aleardi Roof Apartment

The price is AED 486
AED 1,057 total
includes taxes & fees
25 May - 26 May
Mamo Florence - Aleardi Roof Apartment

Piattellina 8 Apartment

9.0 out of 10, Wonderful, (4)
"Beautiful location "
Piattellina 8 Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What is Santo Spirito like?

Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.

What's the best accommodation in Santo Spirito?

Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 8-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include AdAstra Suites and Ottantotto Firenze.

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 455 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.

Where can I learn more about changing or cancelling my trip to Santo Spirito?

To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.

What can I see and do in this Florence neighborhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. Favorite places to visit in the surrounding area include Piazza di Santa Maria Novella, Uffizi Gallery, and Cathedral of Santa Maria del Fiore. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.