Find Luxury Hotels in Santo Spirito

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Check availability on Santo Spirito Luxury Hotels

Tonight
8 May - 9 May
Tomorrow
9 May - 10 May
This weekend
9 May - 11 May
Next weekend
16 May - 18 May

Compare Santo Spirito Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Palazzo Guicciardini
Junior Suite (4 pax) | Premium bedding, minibar, in-room safe, individually decorated

Palazzo Guicciardini

9.4 out of 10, Exceptional, (146)
"This is a small boutique hotel 5 minutes walk from the ponte Vecchio bridge! The staff were so kind and gave us a map of the city and gave us information on great things to see and restaurants to try! The hotel was beautiful and the room was HUGE and property very clean! Our only issue was when typing in the name of the hotel on Google maps, it had our Uber drop us off at a historical sight a couple blocks away due to the two having the same name- this error is mostly our bad because we didn’t...
Palazzo Guicciardini
La Terrazza su Boboli
Food and drink

La Terrazza su Boboli

9.6 out of 10, Exceptional, (32)
"Un bel B&B con gestione molto professionale e cortese. Anche se non in centro, comodo al centro. La terrazza e' stupenda."
La Terrazza su Boboli
UNA HOTELS Vittoria Firenze
Garden

UNA HOTELS Vittoria Firenze

4.0 star property
8.4 out of 10, Very Good, (1000)
"."
The price is AED 653
AED 776 total
includes taxes & fees
11 May - 12 May
UNA HOTELS Vittoria Firenze
Convitto della Calza - Holiday Home
Chapel

Convitto della Calza - Holiday Home

7.8 out of 10, Good, (145)
Convitto della Calza - Holiday Home
Hotel Palazzo Guadagni
Lounge

Hotel Palazzo Guadagni

3.0 star property
9.0 out of 10, Wonderful, (191)
"Worth the stay and I highly recommend"
The price is AED 1,303
AED 1,484 total
includes taxes & fees
1 Jun - 2 Jun
Hotel Palazzo Guadagni
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to Santo Spirito?
Known for its riverfront, Santo Spirito also has some interesting things to see and do including Historic Centre of Florence, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Santo Spirito?
Palazzo Guicciardini is a luxury guesthouse with in-room massages and a bar, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels should I expect to find in Santo Spirito?
Lie in the lap of luxury during your getaway to Santo Spirito in one of Expedia’s 11 luxury hotels.
What's the best time to vacation in Santo Spirito?
The hottest months are usually August and July with an average temperature of 72°F,
  • Coldest months: January, February, December, and March
  • Driest months: July, August, June, and April
  • Rainiest months: November, October, December, and February
What's there to see and do in Santo Spirito?
Enjoy all that Santo Spirito has to offer when you visit Historic Centre of Florence, Porta Romana, and Piazza Santo Spirito. If you have a bit of extra time while you’re in the area, you might want to check out Santo Spirito Basilica and Arno River.