Find Luxury Hotels in Santo Spirito

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Pick from 7 Santo Spirito Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Palazzo Guicciardini
9.2 out of 10, Wonderful, (140)
"The place is located in a nice area a few minutes away from the city center. Rooms are very nice and clean! Highly recommended! Note: only sweet breakfast is available :)"
The price is AED 491
AED 574 total
includes taxes & fees
12 Dec - 13 Dec
Palazzo Guicciardini
La Terrazza su Boboli
9.6 out of 10, Exceptional, (32)
"An overnight stay as we travelled from Italy to France. A great and comfortable night and fantastic breakfast."
La Terrazza su Boboli
UNAHOTELS Vittoria Firenze
4.0 star property
8.4 out of 10, Very Good, (1022)
"Reception"
The price is AED 306
AED 384 total
includes taxes & fees
8 Dec - 9 Dec
UNAHOTELS Vittoria Firenze
Convitto della Calza - Holiday Home
7.8 out of 10, Good, (145)
"Clean, fair for the price Three stars at most Staff were very friendly A short bus ride away from city attractions Bus stop outside the hotel"
Convitto della Calza - Holiday Home
Hotel Palazzo Guadagni
3.0 star property
9.0 out of 10, Wonderful, (185)
"The first room we had we were not impressed. The staff was quick to fix it and the next night we had a much better room. The rooftop was very popular and beautiful to enjoy breakfast on. The location is FANTASTIC. The hotel is quintessential old world Italy. Walking distance to Rialto bridge and Pitti palace. Great restaurants downstairs. LOTS of stairs to get up and down to the hotel but there is an elevator. "
The price is AED 666
AED 776 total
includes taxes & fees
3 Dec - 4 Dec
Hotel Palazzo Guadagni
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to Santo Spirito?
Known for its riverfront, Santo Spirito also has some interesting things to see and do including Historic Centre of Florence, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Santo Spirito?
Palazzo Guicciardini is a luxury guesthouse with in-room massages and a bar, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels should I expect to find in Santo Spirito?
Lie in the lap of luxury during your getaway to Santo Spirito in one of Expedia’s 11 luxury hotels.
What's the best time to vacation in Santo Spirito?
The hottest months are usually August and July with an average temperature of 72°F,
  • Coldest months: January, February, December, and March
  • Driest months: July, August, June, and April
  • Rainiest months: November, October, December, and February
What's there to see and do in Santo Spirito?
Enjoy all that Santo Spirito has to offer when you visit Historic Centre of Florence, Porta Romana, and Piazza Santo Spirito. If you have a bit of extra time while you’re in the area, you might want to check out Pitti Palace and Arno River.