Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of San Frediano with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

4/5(14 reviews)

Find out about the history of San Frediano when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of San Frediano with a stop at Brancacci Chapel. Stroll along the riverfront or visit the churches in this vibrant area.

Brancacci Chapel
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Learn about the history of Historic Centre of Florence, a well-known monument in Florence. Stroll along the area's riverfront or experience its acclaimed art scene.

Historic Centre of Florence
Piazza di Santa Maria Novella which includes a garden, heritage architecture and a church or cathedral

Piazza di Santa Maria Novella

4.5/5(22 reviews)

After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.

Piazza di Santa Maria Novella
Cathedral of Santa Maria del Fiore featuring a city, heritage architecture and a church or cathedral

Cathedral of Santa Maria del Fiore

4.5/5(1,301 reviews)

Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Cathedral of Santa Maria del Fiore

Santo Spirito Hotel Deals

Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (117 reviews)
Muy bueno
"La atención es muy buena, siempre pendientes de todo. El wifi a ratos es muy lento, pero funciona. El hotel está muy bien ubicado."

Reviewed on 31 March 2025

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Foresteria Valdese di Firenze - Casa per Ferie
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
The price is AED 887 per night from Apr 10 to Apr 11
AED 887
AED 1,032 total
includes taxes & fees
10 Apr - 11 Apr
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (957 reviews)
"The building was from the 15th/16th century. Incredibly tasteful renovations keeping old charm."

Reviewed on 5 April 2025

Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
The price is AED 854 per night from Apr 13 to Apr 14
AED 854
AED 995 total
includes taxes & fees
13 Apr - 14 Apr
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (484 reviews)
"Loved this place - probably about a 20min walk from Firenze SMN train station. Beautiful rooms, lovely staff, great location, lots of good restaurants literally round the corner. Would absolutely stay again and have been recommending to family and friends."

Reviewed on 31 March 2025

Hotel Horto Convento
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is AED 514 per night from Apr 13 to Apr 14
AED 514
AED 622 total
includes taxes & fees
13 Apr - 14 Apr
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (985 reviews)
"Was checked in by a lovely lady who made us aware of our VIP status and amenities with it. The hotel was kind enough to hold our luggage when we checked out so we could explore before heading to the train station. They were also kind enough to ask about arranging a taxi for pick up to take us to ..."

Reviewed on 31 December 2024

UNA HOTELS Vittoria Firenze
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
The price is AED 741 per night from Apr 11 to Apr 12
AED 741
AED 863 total
includes taxes & fees
11 Apr - 12 Apr
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (272 reviews)
"The property is right on a piazza and the windows are old school making it a little noisy at night and in the morning when the church bells ring. It was also a hefty walk from the train station over bumpy streets if you have luggage. Having said that the staff was super friendly, the breakfast was ..."

Reviewed on 1 April 2025

Casa Santo Nome di Gesù
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
The price is AED 336 per night from Apr 13 to Apr 14
AED 336
AED 418 total
includes taxes & fees
13 Apr - 14 Apr
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Centre of Florence and Uffizi Gallery are located ...
7.6/10 Good! (63 reviews)
"Slept like a baby"

Reviewed on 8 April 2025

Palazzo Oliveto
See all 454 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Isolotto featuring a park

Isolotto

4.5/5(4 area reviews)

The museums and coffeehouses are just a few things visitors like about Isolotto. Cascine Park and Arno River are worthwhile spots to check out, and you can hop on the metro at Talenti Tram Stop or Batoni Tram Stop to get around the larger area.

Isolotto
Italia my lovely country dal cuore! My father is from Lucca. I went there always I can. This photo was around Val’Dorcia

San Jacopino

4.5/5(15 area reviews)

Even though there aren't top sights in San Jacopino, you can explore the larger area and take in top sights like Piazza di Santa Maria Novella. Jump on the metro at Belfiore Tram Stop to see more of the city.

San Jacopino

Santo Spirito

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