Santo Spirito

Florence
Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Porta Romana

Porta Romana

4/5(14 reviews)

Find out about the history of San Frediano when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Piazza Santo Spirito

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of San Frediano with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and notable monuments in this vibrant area.

Piazza Santo Spirito
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of San Frediano with a stop at Brancacci Chapel. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Brancacci Chapel
Ponte Vecchio which includes a bridge and a river or creek

Ponte Vecchio

4.5/5(2,057 reviews)

Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and notable monuments in this vibrant area.

Ponte Vecchio
Cathedral of Santa Maria del Fiore featuring a city, heritage architecture and a church or cathedral

Cathedral of Santa Maria del Fiore

4.5/5(1,301 reviews)

Find out about the history of Florence with a stop at Cathedral of Santa Maria del Fiore. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Cathedral of Santa Maria del Fiore
Uffizi Gallery

Uffizi Gallery

4.5/5(1,486 reviews)

You can study the exhibits at Uffizi Gallery, a museum with a story of its own, during your travels to Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Uffizi Gallery

Santo Spirito Hotel Deals

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
The price is AED 377 per night from Feb 3 to Feb 4
AED 377
AED 468 total
includes taxes & fees
3 Feb - 4 Feb
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (940 reviews)
"My mom and I loved our stay at the Palazzo Mannaioni in Florence. Roberto made us feel safe the minute we entered the Mannaioni and was very knowledgable of the area and accommodated anything we needed. The suites were in a great location, and the place was pristine."

Reviewed on 26 January 2025

Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
The price is AED 370 per night from Feb 9 to Feb 10
AED 370
AED 460 total
includes taxes & fees
9 Feb - 10 Feb
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (477 reviews)
Great hotel great experience
"The hotel was a renovated convent. Completely modern and very well kept. Beautiful property on the other side of the Arno. It’s about a 15 minute walk from the Ponte Vecchio for reference but still within the historic area of Florence. Lots of shops and restaurants in the are. The service was excellent. ..."

Reviewed on 19 January 2025

Hotel Horto Convento
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
The price is AED 222 per night from Feb 9 to Feb 10
AED 222
AED 287 total
includes taxes & fees
9 Feb - 10 Feb
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Ponte Vecchio and Historic Centre of Florence are located ...
7.4/10 Good! (56 reviews)
"Very good, Perfect base if want to explore. Nothing fancy, has all the basics needed. Simple breakfast but lovely."

Reviewed on 27 January 2025

Palazzo Oliveto
UNAHOTELS Vittoria Firenze
UNAHOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
The price is AED 346 per night from Feb 9 to Feb 10
AED 346
AED 434 total
includes taxes & fees
9 Feb - 10 Feb
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (985 reviews)
"Was checked in by a lovely lady who made us aware of our VIP status and amenities with it. The hotel was kind enough to hold our luggage when we checked out so we could explore before heading to the train station. They were also kind enough to ask about arranging a taxi for pick up to take us to ..."

Reviewed on 31 December 2024

UNAHOTELS Vittoria Firenze
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (269 reviews)
"Everyone was friendly; place was very clean and breakfast was great!"

Reviewed on 4 January 2025

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Casa Santo Nome di Gesù
Hotel Palazzo Guadagni
Hotel Palazzo Guadagni
3 out of 5
Piazza Santo Spirito 9, Florence, FI
The price is AED 599 per night from Feb 5 to Feb 6
AED 599
AED 705 total
includes taxes & fees
5 Feb - 6 Feb
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Uffizi Gallery and ...
9/10 Wonderful! (184 reviews)
"The Hotel is so charming and exactly the vibe you want from Florence. The staff are amazing and they are very helpful guides to the city and have great, chic taste."

Reviewed on 19 December 2024

Hotel Palazzo Guadagni
See all 443 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Palazzo dei Congressi is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Via de' Calzaiuoli and Giotto's Campanile are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Isolotto featuring a park

Isolotto

4.5/5(4 area reviews)

The museums and coffeehouses are just a few things visitors like about Isolotto. Cascine Park and Arno River are worthwhile spots to check out, and you can hop on the metro at Talenti Tram Stop or Batoni Tram Stop to get around the larger area.

Isolotto
Italia my lovely country dal cuore! My father is from Lucca. I went there always I can. This photo was around Val’Dorcia

San Jacopino

4.5/5(15 area reviews)

Even though there aren't top sights in San Jacopino, you can explore the larger area and take in top sights like Visarno Arena. Jump on the metro at Belfiore Tram Stop to see more of the city.

San Jacopino

Santo Spirito

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