Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of San Frediano with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

4/5(14 reviews)

Find out about the history of San Frediano when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its acclaimed art scene.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of San Frediano with a stop at Brancacci Chapel. Stroll along the riverfront or visit the churches in this vibrant area.

Brancacci Chapel
Uffizi Gallery

Uffizi Gallery

4.5/5(1,486 reviews)

Uffizi Gallery is a top museum in Florence with a rich history. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Uffizi Gallery
Cathedral of Santa Maria del Fiore featuring a city, heritage architecture and a church or cathedral

Cathedral of Santa Maria del Fiore

4.5/5(1,301 reviews)

Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Cathedral of Santa Maria del Fiore
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Learn about the history of Historic Centre of Florence, a well-known monument in Florence. Stroll along the area's riverfront or experience its fascinating museums.

Historic Centre of Florence

Santo Spirito Hotel Deals

Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
The price is AED 598 per night from Mar 17 to Mar 18
AED 598
AED 714 total
includes taxes & fees
17 Mar - 18 Mar
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (489 reviews)
"Beautiful"

Reviewed on 26 February 2025

Hotel Horto Convento
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
The price is AED 611 per night from Mar 16 to Mar 17
AED 611
AED 728 total
includes taxes & fees
16 Mar - 17 Mar
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (954 reviews)
Wonderful Property
"Wonderful property! Clean, quiet and the owner/manager was great."

Reviewed on 27 February 2025

Palazzo Mannaioni Suites
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (114 reviews)
"Our room was large, and the staff was friendly and helpful. It is a quick walk over the bridge to the heart of Florence, and there are many good dining options nearby."

Reviewed on 31 October 2024

Get rates
Foresteria Valdese di Firenze - Casa per Ferie
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
The price is AED 449 per night from Mar 23 to Mar 24
AED 449
AED 549 total
includes taxes & fees
23 Mar - 24 Mar
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (983 reviews)
"Was checked in by a lovely lady who made us aware of our VIP status and amenities with it. The hotel was kind enough to hold our luggage when we checked out so we could explore before heading to the train station. They were also kind enough to ask about arranging a taxi for pick up to take us to ..."

Reviewed on 31 December 2024

UNA HOTELS Vittoria Firenze
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
The price is AED 448 per night from Mar 12 to Mar 13
AED 448
AED 540 total
includes taxes & fees
12 Mar - 13 Mar
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (269 reviews)
"Everyone was friendly; place was very clean and breakfast was great!"

Reviewed on 4 January 2025

Casa Santo Nome di Gesù
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
The price is AED 246 per night from Mar 16 to Mar 17
AED 246
AED 319 total
includes taxes & fees
16 Mar - 17 Mar
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Historic Centre of Florence and Uffizi Gallery are located ...
7.6/10 Good! (59 reviews)
"The property was very clean and quiet at night. I enjoyed how cleanly the place was and the staff were very nice especially with breakfast. Would stay again. Around a 30 min walk from the main attractions across the river."

Reviewed on 17 February 2025

Palazzo Oliveto
See all 450 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Isolotto featuring a park

Isolotto

4.5/5(4 area reviews)

The museums and coffeehouses are just a few things visitors like about Isolotto. Cascine Park and Arno River are worthwhile spots to check out, and you can hop on the metro at Talenti Tram Stop or Batoni Tram Stop to get around the larger area.

Isolotto
Italia my lovely country dal cuore! My father is from Lucca. I went there always I can. This photo was around Val’Dorcia

San Jacopino

4.5/5(15 area reviews)

Even though there aren't top sights in San Jacopino, you can explore the larger area and take in top sights like Piazza di Santa Maria Novella. Jump on the metro at Belfiore Tram Stop to see more of the city.

San Jacopino

Santo Spirito

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