Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of San Frediano with a stop at Piazza Santo Spirito. Discover the fascinating museums and stunning cathedral in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

4/5(14 reviews)

Find out about the history of San Frediano when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of San Frediano with a stop at Brancacci Chapel. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Brancacci Chapel
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Learn about the history of Historic Centre of Florence, a well-known monument in Florence. Stroll along the area's riverfront or experience its fascinating museums.

Historic Centre of Florence
Uffizi Gallery

Uffizi Gallery

4.5/5(1,486 reviews)

Uffizi Gallery is a top museum in Florence with a rich history. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Uffizi Gallery
Piazza di Santa Maria Novella which includes a garden, heritage architecture and a church or cathedral

Piazza di Santa Maria Novella

4.5/5(22 reviews)

After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the acclaimed art scene in this vibrant area.

Piazza di Santa Maria Novella

Santo Spirito Hotel Deals

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (945 reviews)
"My mom and I loved our stay at the Palazzo Mannaioni in Florence. Roberto made us feel safe the minute we entered the Mannaioni and was very knowledgable of the area and accommodated anything we needed. The suites were in a great location, and the place was pristine."

Reviewed on 26 January 2025

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Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
The price is AED 368 per night from Feb 23 to Feb 24
AED 368
AED 458 total
includes taxes & fees
23 Feb - 24 Feb
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (480 reviews)
"We meet here for three days with a group of friends. Two of us had cars so the hotel parking was convenient. Cost was €25 per night to park. The hotel was a wonderful calm oasis in the middle of a bustling city. The staff were excellent. They provided great restaurant recommendations, made great ..."

Reviewed on 13 February 2025

Hotel Horto Convento
Palazzo Oliveto
Palazzo Oliveto
Via Monte Oliveto, 32, Florence, FI
The price is AED 210 per night from Feb 20 to Feb 21
AED 210
AED 277 total
includes taxes & fees
20 Feb - 21 Feb
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Ponte Vecchio and Historic Centre of Florence are located ...
7.4/10 Good! (56 reviews)
"Very good, Perfect base if want to explore. Nothing fancy, has all the basics needed. Simple breakfast but lovely."

Reviewed on 27 January 2025

Palazzo Oliveto
La Torre Del Cestello
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
The price is AED 312 per night from Feb 18 to Feb 19
AED 312
AED 389 total
includes taxes & fees
18 Feb - 19 Feb
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Historic Centre of Florence and Uffizi ...
9/10 Wonderful! (160 reviews)
"I wish they would notify you of parking not available prior to arrival"

Reviewed on 3 January 2025

La Torre Del Cestello
Casa Santo Nome di Gesù
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (267 reviews)
"Everyone was friendly; place was very clean and breakfast was great!"

Reviewed on 4 January 2025

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Casa Santo Nome di Gesù
Ottantotto Firenze
Ottantotto Firenze
Via dei Serragli 88, Florence, FI
The price is AED 607 per night from Feb 25 to Feb 26
AED 607
AED 721 total
includes taxes & fees
25 Feb - 26 Feb
Stay at this guesthouse in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (150 reviews)
"We had such a wonderful stay here. A gorgeous boutique hotel in a great location, easy to walk to all the main attractions. The staff are absolutely lovely and very helpful. The complimentary breakfast was delicious and had a great variety. The best part is the style of the hotel, it is absolutely ..."

Reviewed on 3 January 2025

Ottantotto Firenze
See all 454 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Historic Centre of Florence is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Piazza della Repubblica are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Uffizi Gallery and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Isolotto featuring a park

Isolotto

4.5/5(4 area reviews)

The museums and coffeehouses are just a few things visitors like about Isolotto. Cascine Park and Arno River are worthwhile spots to check out, and you can hop on the metro at Talenti Tram Stop or Batoni Tram Stop to get around the larger area.

Isolotto
Italia my lovely country dal cuore! My father is from Lucca. I went there always I can. This photo was around Val’Dorcia

San Jacopino

4.5/5(15 area reviews)

Even though there aren't top sights in San Jacopino, you can explore the larger area and take in top sights like Historic Centre of Florence. Jump on the metro at Belfiore Tram Stop to see more of the city.

San Jacopino

Santo Spirito

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