Photo by Linda Cronan

Find hotels in Medical Center District, San Antonio from AED 169

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Check prices for these dates

Tonight
3 Mar - 4 Mar
Tomorrow
4 Mar - 5 Mar
This weekend
7 Mar - 9 Mar
Next weekend
14 Mar - 16 Mar

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Discover 4,282 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Front of property

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

2.5 star property
8.6 out of 10, Excellent, (2287)
"All good!!!!!"
The price is AED 326
AED 385 total
includes taxes & fees
4 Mar - 5 Mar
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Park Inn by Radisson
Reception

Park Inn by Radisson

2.0 star property
7.0 out of 10, Good, (1000)
"Believe hotel is being remodeled. Room was clean but very bare. Just two chairs, and the counter with microwave and fridge. No chest, dresser, place to keep belongings off the floor. No table. Breakfast was mini oranges and packaged individual mini muffins. No frills. No extras. Clean bed. Clean room. Clean bathroom. Decent shower pressure."
The price is AED 275
AED 321 total
includes taxes & fees
4 Mar - 5 Mar
Park Inn by Radisson
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Lobby

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (777)
"AFTER 5 NO ONE ANWERS THE PHONE TRY OVER AN HOUR TO GET SHUTTLE SERVICE FROM THE AIRPORT. "
The price is AED 340
AED 397 total
includes taxes & fees
9 Mar - 10 Mar
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Lobby

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1219)
"Clean,spacious room, fantastic bed, premium bedding, good breakfast "
The price is AED 367
AED 434 total
includes taxes & fees
24 Mar - 25 Mar
Drury Inn & Suites San Antonio Northwest Medical Center
OYO Inn & Suites Medical Center San Antonio
Room, 2 Queen Beds | Desk, iron/ironing board, Internet, bed sheets

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (198)
"I love this place lovely "
The price is AED 224
AED 262 total
includes taxes & fees
4 Mar - 5 Mar
OYO Inn & Suites Medical Center San Antonio
San Antonio Marriott Northwest Medical Center
Lobby

San Antonio Marriott Northwest Medical Center

3.5 star property
8.2 out of 10, Very Good, (1007)
"IT Was just nice!"
The price is AED 360
AED 428 total
includes taxes & fees
30 Mar - 31 Mar
San Antonio Marriott Northwest Medical Center
SpringHill Suites by Marriott San Antonio Medical Center/NW
Premium bedding, pillowtop beds, in-room safe, desk

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1005)
"Room size was good for the price. To many homeless around the area asking for money."
The price is AED 382
AED 452 total
includes taxes & fees
9 Mar - 10 Mar
SpringHill Suites by Marriott San Antonio Medical Center/NW
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Property amenity

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1004)
"Convenient location right next to I -10. Clean and quiet. Breakfast included was a plus."
The price is AED 209
AED 244 total
includes taxes & fees
23 Mar - 24 Mar
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Courtyard by Marriott Medical Center San Antonio
Lobby

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.6 out of 10, Excellent, (1001)
"Convenient "
The price is AED 360
AED 425 total
includes taxes & fees
23 Mar - 24 Mar
Courtyard by Marriott Medical Center San Antonio
Atria Inn & Suites
Front of property

Atria Inn & Suites

2.0 star property
8.0 out of 10, Very Good, (182)
"Excellent price, area is quite, close to Mays Clinic."
The price is AED 202
AED 236 total
includes taxes & fees
4 Mar - 5 Mar
Atria Inn & Suites
Studio 6 San Antonio, Tx - Northwest Medical Center
Desk, laptop workspace, blackout drapes, free WiFi

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.0 out of 10, Good, (120)
"Always hesitant with budget friendly motels but this one by far exceeded expectations. The staff was very friendly and the room was well equipped and VERY clean. No awkward smells or anything. Bedding was very clean and everything worked in the room (TV, refrigerator, microwave, toaster, coffee machine) Stand in shower was very clean. Great locations, close to several restaurants with a convenience store in the back of the hotel. Will stay here again."
The price is AED 184
AED 214 total
includes taxes & fees
4 Mar - 5 Mar
Studio 6 San Antonio, Tx - Northwest Medical Center
Studio 6 San Antonio, TX - Medical Center
Desk, laptop workspace, free WiFi, bed sheets

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (666)
"The staff was pleasant and friendly. One person behind the counter she was absolutely the best. Our room was ok and the area was ok. I’m going to complain a little about some bugs we had in the room and the very poor water pressure. Other than that it was a great place to rest our tired heads. BTW There was a faint smell of MJ in the restroom and a burn on the toilet lid that looks like they had been smoking something in there. I asked for a non smoking room."
The price is AED 220
AED 268 total
includes taxes & fees
4 Mar - 5 Mar
Studio 6 San Antonio, TX - Medical Center
Motel 6 San Antonio, TX - Northwest Medical Center
Free WiFi, bed sheets

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (1002)
"i mean you get what you payed for it served its purpose. no problems"
The price is AED 169
AED 200 total
includes taxes & fees
4 Mar - 5 Mar
Motel 6 San Antonio, TX - Northwest Medical Center
Flex Studios
Basic Room, Multiple Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets

Flex Studios

2.5 star property
5.8 out of 10, (451)
"Very convenient location. Staff was very friendly and the room was tidy and clean. Great stay for the price."
The price is AED 190
AED 225 total
includes taxes & fees
4 Mar - 5 Mar
Flex Studios
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma
Premium bedding, down comforters, individually decorated

La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

2.5 star property
8.0 out of 10, Very Good, (971)
"This property put us within a mile from our intended destination. The hotel was clean, beds were comfortable and check in and out were easy. I would stay again and I would recommend. "
The price is AED 303
AED 348 total
includes taxes & fees
24 Mar - 25 Mar
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma
Best Western Plus Atrium Inn
Property amenity

Best Western Plus Atrium Inn

2.5 star property
8.6 out of 10, Excellent, (1002)
"Clean"
The price is AED 332
AED 381 total
includes taxes & fees
5 Mar - 6 Mar
Best Western Plus Atrium Inn
Super 8 by Wyndham Universal City
Seasonal outdoor pool

Super 8 by Wyndham Universal City

2.0 star property
6.6 out of 10, (1002)
"The bed was a bit high seem like I needed a step to get on but it was comfy."
The price is AED 175
AED 201 total
includes taxes & fees
3 Apr - 4 Apr
Super 8 by Wyndham Universal City
Best Western Plus San Antonio East Inn & Suites
Spa

Best Western Plus San Antonio East Inn & Suites

2.5 star property
9.0 out of 10, Wonderful, (560)
"Staff was amazing. It’s quiet. Service was just amazing. "
The price is AED 397
AED 463 total
includes taxes & fees
23 Mar - 24 Mar
Best Western Plus San Antonio East Inn & Suites
stayAPT Suites San Antonio-Randolph
Courtyard

stayAPT Suites San Antonio-Randolph

2.5 star property
8.8 out of 10, Excellent, (311)
"The property was clean, very well lit parking, it was nice and open. The staff was super nice the room was so cool and clean I loved it 10 out of 10 would super recommend "
The price is AED 356
AED 409 total
includes taxes & fees
4 Mar - 5 Mar
stayAPT Suites San Antonio-Randolph
La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
Exterior

La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein

2.5 star property
5.6 out of 10, (1235)
"Pleasantly surprised. This La Quinta has recently updated rooms that have been repainted. The sheets were clean and the bed was comfortable. The fridge, coffee maker, iron, ironing board, and microwave were useful. Breakfast was minimal but I had no complaints. For the price this worked out great. You might need to request daily service. That’s not a given. In 4 days, housekeeping never came by on their own. Otherwise, pretty solid experience. "
The price is AED 221
AED 254 total
includes taxes & fees
1 Apr - 2 Apr
La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is Medical Center District like?

Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighborhood.

What's a favorite place to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 122 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.

Where can I learn more about changing or cancelling my trip to Medical Center District?

For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.

What can I see and do in this San Antonio neighborhood?

A few attractions you might want to check out while you're in Medical Center District are USAA Corporate Office Headquarters and The San Antonio Art Institute. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.