Photo by Linda Cronan

Find hotels in Medical Center District, San Antonio from AED 144

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Discover 4,256 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

2.5 star property
8.6 out of 10, Excellent, (2207)
"Staff very nice"
The price is AED 326
AED 386 total
includes taxes & fees
31 Jan - 1 Feb
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (752)
"Excellent and quick service. Close to nearby hospitals, dining, and shopping. Only complaint was a noisy upstairs guest, but management got them to quiet down and the rest of the stay was great."
The price is AED 338
AED 395 total
includes taxes & fees
7 Feb - 8 Feb
Fairfield Inn & Suites by Marriott San Antonio Medical Center

San Antonio Marriott Northwest Medical Center

3.5 star property
8.2 out of 10, Very Good, (1009)
"It was the perfect location for us. The mobility impaired room was great. "
The price is AED 364
AED 432 total
includes taxes & fees
31 Jan - 1 Feb
San Antonio Marriott Northwest Medical Center

Clarion Pointe near Medical Center

2.5 star property
7.0 out of 10, Good, (1546)
"Very comfortable there"
The price is AED 167
AED 198 total
includes taxes & fees
2 Mar - 3 Mar
Clarion Pointe near Medical Center

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.6 out of 10, Excellent, (1002)
"Property was quiet and well maintained "
The price is AED 360
AED 425 total
includes taxes & fees
6 Feb - 7 Feb
Courtyard by Marriott Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (191)
"It was comfortable "
The price is AED 212
AED 269 total
includes taxes & fees
12 Feb - 13 Feb
OYO Inn & Suites Medical Center San Antonio

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1207)
"My stay was excellent, but I can't give 5 stars because the rooms need to be updated. The dark carpeting and the color are horrible for today's standards. However, the staff are wonderful, the amenities including free breakfast and dinner and 3 drinks for free per day is fantastic. The parking for the stay is behind a gate, so I felt safe leaving my vehicle outside and not wondering if I was going to come back to a stolen or broken into vehicle. As for sleep quality, the beds are a little soft...
The price is AED 367
AED 434 total
includes taxes & fees
2 Feb - 3 Feb
Drury Inn & Suites San Antonio Northwest Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1010)
"."
The price is AED 215
AED 252 total
includes taxes & fees
10 Feb - 11 Feb
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1001)
"This is a great property! Checkin was quick, the room was spacious and clean and the heat worked perfectly. Breakfast offerings were good too. The door to the toilet/shower area swings inches from the toilet so you have to maneuver a bit to close the door behind you. The curtains let in light at the bottom and there was a small item left there from the previous guest. Overall a very nice stay. Would definitely stay there again."
The price is AED 382
AED 452 total
includes taxes & fees
1 Feb - 2 Feb
SpringHill Suites by Marriott San Antonio Medical Center/NW

Atria Inn & Suites

2.0 star property
8.0 out of 10, Very Good, (169)
"Easy to get to parking is a breeze check in fast I enjoyed my stay👍"
The price is AED 184
AED 214 total
includes taxes & fees
3 Feb - 4 Feb
Atria Inn & Suites

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.2 out of 10, Good, (112)
"Studio 6 is part of Motel 6 that was right next to it. I heard another guest complain that their room was very dirty and smelled. Our room was OK. It had a small kitchenette, and the beds were clean. The biggest downside was that it's right next to the highway, and there is a lot of road noise from the cars passing by. "
The price is AED 184
AED 214 total
includes taxes & fees
2 Feb - 3 Feb
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (659)
"The heater has burning smell "
The price is AED 202
AED 246 total
includes taxes & fees
9 Feb - 10 Feb
Studio 6 San Antonio, TX - Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (1002)
"One night in San Antonio. Just needed a place to stay overnight. No frills, typical Motel 6. Clean room, bath and average bed. Price good for area. "
The price is AED 169
AED 200 total
includes taxes & fees
2 Feb - 3 Feb
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

2.5 star property
5.8 out of 10, (449)
"Very convenient location. Staff was very friendly and the room was tidy and clean. Great stay for the price."
The price is AED 190
AED 225 total
includes taxes & fees
2 Feb - 3 Feb
Flex Studios

La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

2.5 star property
8.0 out of 10, Very Good, (958)
"It was good for the price "
The price is AED 281
AED 323 total
includes taxes & fees
2 Feb - 3 Feb
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

Best Western Plus Atrium Inn

2.5 star property
8.6 out of 10, Excellent, (993)
"George was extremely helpful with my needs. He was knowledgeable about the hotel and the surrounding area which included things to do."
The price is AED 332
AED 381 total
includes taxes & fees
2 Feb - 3 Feb
Best Western Plus Atrium Inn

Super 8 by Wyndham Universal City

2.0 star property
6.6 out of 10, (1003)
"Quiet "
The price is AED 144
AED 165 total
includes taxes & fees
2 Mar - 3 Mar
Super 8 by Wyndham Universal City

Best Western Plus San Antonio East Inn & Suites

2.5 star property
9.0 out of 10, Wonderful, (555)
"I thought the room was clean.and the beds and pillows were comfortable. Close to the River walk. Is why we stayed there."
The price is AED 397
AED 463 total
includes taxes & fees
23 Feb - 24 Feb
Best Western Plus San Antonio East Inn & Suites

stayAPT Suites San Antonio-Randolph

2.5 star property
8.8 out of 10, Excellent, (288)
"Very private space "
The price is AED 364
AED 417 total
includes taxes & fees
31 Jan - 1 Feb
stayAPT Suites San Antonio-Randolph

Best Western Garden Inn

2.5 star property
8.2 out of 10, Very Good, (1002)
" Nice and clean, pleasant staff. "
The price is AED 257
AED 300 total
includes taxes & fees
31 Jan - 1 Feb
Best Western Garden Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is Medical Center District like?

Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighborhood.

What's a favorite place to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 130 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.

Where can I learn more about changing or cancelling my trip to Medical Center District?

For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.

What can I see and do in this San Antonio neighborhood?

A few attractions you might want to check out while you're in Medical Center District are USAA Corporate Office Headquarters and The San Antonio Art Institute. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.