Photo by Linda Cronan

Find hotels in Medical Center District, San Antonio from AED 162

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Check prices for these dates

Tonight
19 May - 20 May
Tomorrow
20 May - 21 May
This weekend
23 May - 25 May
Next weekend
30 May - 1 Jun

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Discover 4,361 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Lobby

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (852)
"Great place to stay. "
The price is AED 338
AED 395 total
includes taxes & fees
1 Jun - 2 Jun
Fairfield Inn & Suites by Marriott San Antonio Medical Center
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Front of property

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
8.6 out of 10, Excellent, (2520)
"Excellent stay very friendly staff and best of all Clean very clean "
The price is AED 364
AED 431 total
includes taxes & fees
20 May - 21 May
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Drury Inn & Suites San Antonio Northwest Medical Center
Lobby

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1237)
"Amazing staff, very clean and great location."
The price is AED 367
AED 434 total
includes taxes & fees
21 May - 22 May
Drury Inn & Suites San Antonio Northwest Medical Center
San Antonio Marriott Northwest Medical Center
Cocktail bar

San Antonio Marriott Northwest Medical Center

3.5 star property
8.4 out of 10, Very Good, (1017)
"Great location, clean hotel, good bar and restaurant "
The price is AED 349
AED 415 total
includes taxes & fees
25 May - 26 May
San Antonio Marriott Northwest Medical Center
Park Inn by Radisson
Lobby

Park Inn by Radisson

2.0 star property
7.0 out of 10, Good, (1006)
"Very nice and quiet place to stay in the medical center. "
The price is AED 245
AED 286 total
includes taxes & fees
22 May - 23 May
Park Inn by Radisson
SpringHill Suites by Marriott San Antonio Medical Center/NW
Premium bedding, pillowtop beds, in-room safe, desk

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1005)
"Perfect to family with little children. "
The price is AED 400
AED 473 total
includes taxes & fees
31 May - 1 Jun
SpringHill Suites by Marriott San Antonio Medical Center/NW
Courtyard by Marriott Medical Center San Antonio
Lobby

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.6 out of 10, Excellent, (1007)
"Good hotel "
The price is AED 360
AED 425 total
includes taxes & fees
30 May - 31 May
Courtyard by Marriott Medical Center San Antonio
Studio 6 San Antonio, Tx - Northwest Medical Center
Desk, laptop workspace, blackout drapes, free WiFi

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.0 out of 10, Good, (139)
"It was really nice will be staying here again "
The price is AED 162
AED 189 total
includes taxes & fees
1 Jun - 2 Jun
Studio 6 San Antonio, Tx - Northwest Medical Center
Atria Inn & Suites
Front of property

Atria Inn & Suites

2.0 star property
7.8 out of 10, Good, (215)
"I like that the staff is extremely kind and the "
The price is AED 202
AED 236 total
includes taxes & fees
27 May - 28 May
Atria Inn & Suites
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Property amenity

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1000)
"The breakfast was really good and all the staff were so nice!!"
The price is AED 225
AED 262 total
includes taxes & fees
21 May - 22 May
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
OYO Inn & Suites Medical Center San Antonio
Room, 2 Queen Beds | Desk, iron/ironing board, Internet, bed sheets

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (208)
"Quiet area "
The price is AED 235
AED 274 total
includes taxes & fees
20 May - 21 May
OYO Inn & Suites Medical Center San Antonio
Studio 6 San Antonio, TX - Medical Center
Desk, laptop workspace, free WiFi, bed sheets

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (705)
"The landscape of hotel ,but the room are aged. "
The price is AED 170
AED 208 total
includes taxes & fees
2 Jun - 3 Jun
Studio 6 San Antonio, TX - Medical Center
Motel 6 San Antonio, TX - Northwest Medical Center
Free WiFi, bed sheets

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (1005)
"It was very clean and nice and quiet."
The price is AED 162
AED 191 total
includes taxes & fees
26 May - 27 May
Motel 6 San Antonio, TX - Northwest Medical Center
Flex Studios
Basic Room, Multiple Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets

Flex Studios

2.5 star property
5.8 out of 10, (466)
"The staff was very helpful and accommodating. And they were super friendly!"
The price is AED 190
AED 225 total
includes taxes & fees
20 May - 21 May
Flex Studios
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma
Premium bedding, down comforters, individually decorated

La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

3.0 star property
8.0 out of 10, Very Good, (1015)
"It was a great stay"
The price is AED 297
AED 341 total
includes taxes & fees
15 Jun - 16 Jun
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma
Best Western Plus Atrium Inn
Property amenity

Best Western Plus Atrium Inn

2.5 star property
8.8 out of 10, Excellent, (1010)
"Very nice place to stay! "
The price is AED 332
AED 381 total
includes taxes & fees
26 May - 27 May
Best Western Plus Atrium Inn
Super 8 by Wyndham Universal City
Seasonal outdoor pool

Super 8 by Wyndham Universal City

2.0 star property
6.6 out of 10, (1011)
"Great place to stay! "
The price is AED 165
AED 190 total
includes taxes & fees
8 Jun - 9 Jun
Super 8 by Wyndham Universal City
stayAPT Suites San Antonio-Randolph
Courtyard

stayAPT Suites San Antonio-Randolph

2.5 star property
8.8 out of 10, Excellent, (353)
"Nice and comfortable stay"
The price is AED 384
AED 441 total
includes taxes & fees
27 May - 28 May
stayAPT Suites San Antonio-Randolph
La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
Exterior

La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein

3.0 star property
5.6 out of 10, (1263)
"Location was perfect for us. "
The price is AED 209
AED 240 total
includes taxes & fees
20 May - 21 May
La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
Best Western Garden Inn
Reception

Best Western Garden Inn

2.5 star property
8.2 out of 10, Very Good, (1015)
"Stayed two nights in a row and had an enjoyable stay. "
The price is AED 281
AED 328 total
includes taxes & fees
1 Jun - 2 Jun
Best Western Garden Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most.
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek
Downtown San Antonio map

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Marion Koogler McNay Art Museum featuring art and interior views
Uptown map

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Far West Side map

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak map

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side map

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Frequently asked questions

What is Medical Center District like?

Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighborhood.

What's a favorite place to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 125 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.

Where can I learn more about changing or cancelling my trip to Medical Center District?

For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.

What can I see and do in this San Antonio neighborhood?

USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.