Photo by Linda Cronan

Find 5 Star Hotels in Medical Center District, TX from AED 350

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Check availability on Medical Center District 5 Star Hotels

Tonight
24 Mar - 25 Mar
Tomorrow
25 Mar - 26 Mar
This weekend
28 Mar - 30 Mar
Next weekend
4 Apr - 6 Apr

Compare Medical Center District 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Thompson San Antonio - Riverwalk, by Hyatt
Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)

Thompson San Antonio - Riverwalk, by Hyatt

5.0 star property
9.0 out of 10, Wonderful, (703)
"We thoroughly enjoyed our 30th Anniversary staycation at the Thompson! The staff was amazing and all of the outings that we were driven to in the House Car by Connie were fantastic. The champagne and cheesecake that was unexpectedly delivered to our room for our anniversary was the icing on the cake. We will definitely be back!"
The price is AED 777
AED 1,045 total
includes taxes & fees
13 Apr - 14 Apr
Thompson San Antonio - Riverwalk, by Hyatt
The Luxury Suites at Arrive Eilan
Terrace/patio

The Luxury Suites at Arrive Eilan

5.0 star property
7.4 out of 10, Good, (129)
"Very nice. Easy and Clean"
The Luxury Suites at Arrive Eilan
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Medical Center District.
Riverwalk Plaza

Riverwalk Plaza

100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is AED 350 per night from Apr 8 to Apr 9
AED 350
AED 413 total
includes taxes & fees
8 Apr - 9 Apr
8/10 Very Good! (4,896 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Medical Center District?
The amount you pay for a 5-star hotel in Medical Center District depends on factors such as when you plan to travel and the length of your vacation. An insider tip for bagging the best deal? Use our pricing filters to check out all of the available options for your chosen dates.

  • Search for the lowest price per night from AED 350

What makes a hotel 5 stars in Medical Center District?
From high-end restaurants and all-day gyms to pools and luxury bedding, the 5-star experience in Medical Center District is all about relaxation and luxury. But it requires more than just upscale amenities to receive a 5-star rating. Stays must also offer superb guest-focused services like in-room massages, dry cleaning and laundry and concierge services.
Are there any 5-star all-inclusive resorts in Medical Center District?
Find an upscale getaway that includes your room, meals, activities and entertainment in Medical Center District with our handy filter tool. Search for hotels rated 5 stars and click on the “All inclusive” filter. Have a look at what’s included in the upfront price. This way, you’ll be ready to maximize the premium perks on offer when you arrive.
Are there any 5-star vacation rentals in Medical Center District?
There are no 5-star vacation rentals in Medical Center District on our site, but there are a few other highly rated properties worth checking out. Search through our vacation rentals in Medical Center District to discover the ideal place for your getaway.