Photo by Linda Cronan
Find all hotels by Motel 6 in Medical Center District, TX from AED 164
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Compare rooms and suites by Motel 6 in Medical Center District with rates, reviews, and availability. Most hotels are fully refundable.

Studio 6 San Antonio, TX - Airport
Studio 6 San Antonio, TX - Airport
6.2 out of 10, (1012)
The price is AED 220
AED 260 total
includes taxes & fees
4 May - 5 May

Motel 6 San Antonio, TX - Fiesta Trails
Motel 6 San Antonio, TX - Fiesta Trails
6.6 out of 10, (923)
The price is AED 184
AED 214 total
includes taxes & fees
4 May - 5 May

Motel 6 San Antonio, TX - Fiesta
Motel 6 San Antonio, TX - Fiesta
6.6 out of 10, (1004)
The price is AED 173
AED 204 total
includes taxes & fees
8 May - 9 May

Motel 6 San Antonio, TX - Downtown - Market Square
Motel 6 San Antonio, TX - Downtown - Market Square
6.8 out of 10, (1005)
The price is AED 220
AED 260 total
includes taxes & fees
14 May - 15 May

Motel 6 San Antonio, TX - Sea World North
Motel 6 San Antonio, TX - Sea World North
6.8 out of 10, (501)
The price is AED 176
AED 206 total
includes taxes & fees
19 May - 20 May

Motel 6 San Antonio, TX - Downtown - Alamo Dome
Motel 6 San Antonio, TX - Downtown - Alamo Dome
7.0 out of 10, Good, (991)
The price is AED 217
AED 253 total
includes taxes & fees
8 May - 9 May

Motel 6 San Antonio, TX - West SeaWorld
Motel 6 San Antonio, TX - West SeaWorld
5.8 out of 10, (1002)
The price is AED 164
AED 193 total
includes taxes & fees
5 May - 6 May

Motel 6 San Antonio, TX - Fort Sam Houston
Motel 6 San Antonio, TX - Fort Sam Houston
5.8 out of 10, (1001)
The price is AED 171
AED 202 total
includes taxes & fees
4 May - 5 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Medical Center District hotels
Recent reviews of Medical Center District hotels

La Quinta Inn & Suites by Wyndham San Antonio Downtown
5/5 Excellent
"Great place to stay."
A verified traveler from McAllen stayed at La Quinta Inn & Suites by Wyndham San Antonio Downtown
Posted 19 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Medical Center District Hotels by Brand
Hotels in Medical Center District Neighborhoods
Hotels near popular San Antonio Attractions
- Hotels near USAA Corporate Office Headquarters
- Hotels near South Texas Medical Center
- Hotels near University of Texas Health and Science Center at San Antonio
- Hotels near CHRISTUS Santa Rosa Hospital - Medical Center
- Hotels near Oak Hills Country Club
- Hotels near The San Antonio Art Institute
- Hotels near River Walk
More Accommodation Types in
Explore more hotels
- Hotel Contessa
- Crockett Hotel
- Hyatt Regency San Antonio Riverwalk
- Drury Plaza Hotel San Antonio Airport
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- La Cantera Resort & Spa
- Omni La Mansion del Rio
- Grand Hyatt San Antonio River Walk
- Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
- JW Marriott San Antonio Hill Country Resort & Spa
- Hyatt Regency Hill Country Resort & Spa
- Sonesta ES Suites San Antonio Downtown Alamo Plaza
- La Quinta Inn & Suites by Wyndham San Antonio Airport
- La Quinta Inn & Suites By Wyndham San Antonio At The Rim
- Canopy by Hilton San Antonio Riverwalk
- Best Western Alamo Suites
- Crowne Plaza San Antonio Airport by IHG
- Aiden San Antonio Riverwalk
- Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
- Hilton San Antonio Hill Country