Photo by Linda Cronan

Find 4 Star Hotels in Medical Center District, TX from AEDĀ 350

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Medical Center District 4 Star Hotels

Tonight
6 Apr - 7 Apr
Tomorrow
7 Apr - 8 Apr
Next weekend
11 Apr - 13 Apr
In two weeks
18 Apr - 20 Apr

Compare Medical Center District 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Riverwalk Plaza
Game room

Riverwalk Plaza

4.0 star property
8.2 out of 10, Very Good, (5009)
"Very conveniently located for our plans. As in any city parking was an issue in the area. A lot available but pricy. Worked out if you are planning on coming and going during your stay the valet parking was the way to go. Great staff"
The price is AEDĀ 408
AEDĀ 483 total
includes taxes & fees
22 Apr - 23 Apr
Riverwalk Plaza
Grand Hyatt San Antonio River Walk
Miscellaneous

Grand Hyatt San Antonio River Walk

4.0 star property
9.0 out of 10, Wonderful, (1140)
"I loved the property! Itā€™s was beautiful. The beds were comfortable . We got two free margaritas when we checked in. I just wish I got to experience more of what the property had to offer. I came down there for a basketball game so time kinda flew by. I just didnā€™t like that after hours we ran into some crazy rude people on the river walk. "
The price is AEDĀ 602
AEDĀ 831 total
includes taxes & fees
20 Apr - 21 Apr
Grand Hyatt San Antonio River Walk
Hotel Contessa
Outdoor pool, a heated pool, open 8:00 AM to 10:00 PM, free cabanas

Hotel Contessa

4.0 star property
9.0 out of 10, Wonderful, (3053)
"Extremely helpful and polite staff. The restaurant had delicious food and was right on the riverwalk!"
The price is AEDĀ 663
AEDĀ 844 total
includes taxes & fees
17 Apr - 18 Apr
Hotel Contessa
Hyatt Regency San Antonio Riverwalk
View from property

Hyatt Regency San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (1740)
"Great location! Right on the riverwalk. I donā€™t like the motion activated lights on the sides of the bed, very frustrating when one of my kids gets up in the night and the light turns on. Was hot in the room. Sheets and blankets are soft and comfortable. Staff was amazing, like above and beyond friendly. View from our room of the Alamo was awesome. "
The price is AEDĀ 691
AEDĀ 946 total
includes taxes & fees
20 Apr - 21 Apr
Hyatt Regency San Antonio Riverwalk
The Westin Riverwalk, San Antonio
Breakfast, lunch, dinner served; Italian cuisine

The Westin Riverwalk, San Antonio

4.0 star property
8.8 out of 10, Excellent, (1155)
"Quiet, clean, walkable and great people"
The price is AEDĀ 606
AEDĀ 722 total
includes taxes & fees
17 Apr - 18 Apr
The Westin Riverwalk, San Antonio
Hotel Valencia Riverwalk
Terrace/patio

Hotel Valencia Riverwalk

4.5 star property
9.4 out of 10, Exceptional, (1876)
"Absolutely loved The Valencia! Staff was all great! First class property! "
The price is AEDĀ 592
AEDĀ 778 total
includes taxes & fees
20 Apr - 21 Apr
Hotel Valencia Riverwalk
Canopy by Hilton San Antonio Riverwalk
Terrace/patio

Canopy by Hilton San Antonio Riverwalk

4.0 star property
9.4 out of 10, Exceptional, (1473)
"Amazing hotel and great location! Our waiter PJ, was outstanding and literally was our ā€œtour guideā€ with all his great recommendation. Love this place.. very special."
The price is AEDĀ 706
AEDĀ 850 total
includes taxes & fees
4 May - 5 May
Canopy by Hilton San Antonio Riverwalk
Plaza San Antonio Hotel & Spa, Autograph Collection
Outdoor pool, open 9:00 AM to 10:00 PM, cabanas (surcharge)

Plaza San Antonio Hotel & Spa, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (426)
"Everuthingbwas amazing! Customer service is outstanding!!! "
The price is AEDĀ 654
AEDĀ 885 total
includes taxes & fees
20 Apr - 21 Apr
Plaza San Antonio Hotel & Spa, Autograph Collection
Omni La Mansion del Rio
Outdoor pool

Omni La Mansion del Rio

4.0 star property
9.4 out of 10, Exceptional, (2541)
"Right on the Riverwalk, near many restaurants. 15 mins from the airport. The pool was nice, staff was friendly and polite. Would stay here again and recommend to anyone thinkinh of coming to the area."
The price is AEDĀ 660
AEDĀ 791 total
includes taxes & fees
19 Apr - 20 Apr
Omni La Mansion del Rio
InterContinental San Antonio Riverwalk by IHG
2 restaurants, breakfast served

InterContinental San Antonio Riverwalk by IHG

4.5 star property
9.4 out of 10, Exceptional, (325)
"Kayla at the front desk was absolutely wonderful she couldnā€™t have been more helpful! The entire staff went above and beyond, making my stay truly enjoyable. This will definitely be my go-to spot whenever Iā€™m in San Antonio. Highly recommend!"
The price is AEDĀ 729
AEDĀ 988 total
includes taxes & fees
17 Apr - 18 Apr
InterContinental San Antonio Riverwalk by IHG
Element San Antonio Riverwalk
Bar (on property)

Element San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (704)
"It was very easy to get to the riverfront"
The price is AEDĀ 438
AEDĀ 518 total
includes taxes & fees
4 May - 5 May
Element San Antonio Riverwalk
The Westin San Antonio North
Indoor pool, outdoor pool

The Westin San Antonio North

4.0 star property
8.6 out of 10, Excellent, (1004)
"Staff was very professional and courteous. Great Hotel."
The price is AEDĀ 408
AEDĀ 488 total
includes taxes & fees
19 Apr - 20 Apr
The Westin San Antonio North
JW Marriott San Antonio Hill Country Resort & Spa
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott San Antonio Hill Country Resort & Spa

4.5 star property
8.8 out of 10, Excellent, (1005)
"Not crowded. "
The price is AEDĀ 1,466
AEDĀ 1,938 total
includes taxes & fees
13 Apr - 14 Apr
JW Marriott San Antonio Hill Country Resort & Spa
AC Hotel by Marriott San Antonio Riverwalk
View from property

AC Hotel by Marriott San Antonio Riverwalk

4.0 star property
8.8 out of 10, Excellent, (709)
"."
The price is AEDĀ 438
AEDĀ 518 total
includes taxes & fees
20 Apr - 21 Apr
AC Hotel by Marriott San Antonio Riverwalk
La Cantera Resort & Spa
Private pool

La Cantera Resort & Spa

4.0 star property
8.8 out of 10, Excellent, (1004)
"The hotel and spa are so beautiful and peaceful. The whole staff was wonderful, kind, and so helpful! The food, service, and stay were all excellent. I am so grateful for the special time with my family after a much needed getaway after the death of a loved one. Thank you to all the staff who made our stay so special! "
The price is AEDĀ 959
AEDĀ 1,299 total
includes taxes & fees
27 Apr - 28 Apr
La Cantera Resort & Spa
San Antonio Marriott Rivercenter on the River Walk
Exterior

San Antonio Marriott Rivercenter on the River Walk

4.0 star property
8.8 out of 10, Excellent, (1001)
"Receptionist didnā€™t explain anything to me about putting a large amount of money as a place holder when I checked in. I had a connecting room, but the door lock was a bit unreliable & I can the person talking on the phone in the room next to mine. The pillows were all feather and had no volume, my neck would hurt if I didnā€™t stack 2-3 pillows together. the elevators were great, little food place/coffee shop was good. No one cleaned the tables outside that though. Despite all that, I had a good...
The price is AEDĀ 606
AEDĀ 814 total
includes taxes & fees
20 Apr - 21 Apr
San Antonio Marriott Rivercenter on the River Walk
Hilton Garden Inn San Antonio Downtown Riverwalk
Reception

Hilton Garden Inn San Antonio Downtown Riverwalk

4.0 star property
8.4 out of 10, Very Good, (1010)
"Really enjoyed my stay! The staff was so friendly and kind. Angel at the front desk was very accommodating. Will stay here again when I come back to San Antonio! šŸ˜Š"
The price is AEDĀ 350
AEDĀ 425 total
includes taxes & fees
20 Apr - 21 Apr
Hilton Garden Inn San Antonio Downtown Riverwalk
Kimpton Santo by IHG
Outdoor pool

Kimpton Santo by IHG

4.5 star property
9.2 out of 10, Wonderful, (229)
"Staff friendly our room was beautiful , we used valet parking multiple times it was excellent . Scan the code and give them 10 minutes to grab your car. No waiting at all for us. Thanks for a great time."
The price is AEDĀ 777
AEDĀ 1,015 total
includes taxes & fees
10 Apr - 11 Apr
Kimpton Santo by IHG
Mokara Hotel & Spa San Antonio
Couples treatment rooms, sauna, hot tub, steam room, body treatments

Mokara Hotel & Spa San Antonio

4.5 star property
9.6 out of 10, Exceptional, (1001)
"Best place to stay in San Antonio"
The price is AEDĀ 855
AEDĀ 1,014 total
includes taxes & fees
6 May - 7 May
Mokara Hotel & Spa San Antonio
Marriott San Antonio Riverwalk
Meeting facility

Marriott San Antonio Riverwalk

4.0 star property
8.8 out of 10, Excellent, (1002)
"We parked at the Convention Center and saved $50.00 a day in parking. lol"
The price is AEDĀ 606
AEDĀ 813 total
includes taxes & fees
13 Apr - 14 Apr
Marriott San Antonio Riverwalk
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue, San Antonio, TX
The price is AEDĀ 777 per night from Apr 13 to Apr 14
AEDĀ 777
AEDĀ 1,045 total
includes taxes & fees
13 Apr - 14 Apr
9/10 Wonderful! (718 reviews)
Still don't see what you're looking for?
See all properties in Medical Center District.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Medical Center District?
The Westin San Antonio North is highly praised by Expedia guests. This 4-star hotel located around Medical Center District guarantees a warm and inviting atmosphere and plenty of handy amenities.
How much does it cost to stay in a 4-star hotel in Medical Center District?
We can help you quickly find the ideal 4-star hotel for your trip to Medical Center District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from AED 777

What's the difference between 5-star and 4-star hotels in Medical Center District?
Give yourself the luxury treatment during your Medical Center District escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically packed with amenities such as large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more lavish and unforgettable one. Concierge assistance, elegant furnishings and world-class dining are a few of the first-rate conveniences and services youā€™ll likely have access to.
Does Medical Center District have any 4-star all-inclusive resorts?
Finding your dream hotel in Medical Center District is as simple as entering your travel dates and selecting our ā€œAll inclusiveā€ filter. Stay and play where almost everything is already taken care of like your meals, room, entertainment and activities, or go for a standard 4-star resort in or around this sought-after destination.