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Find 4 Star Hotels in Medical Center District, TX from AED 297
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Compare Medical Center District 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Riverwalk Plaza
Riverwalk Plaza
8.2 out of 10, Very Good, (5228)
The price is AED 320
AED 379 total
includes taxes & fees
15 Jun - 16 Jun

Grand Hyatt San Antonio River Walk
Grand Hyatt San Antonio River Walk
9.0 out of 10, Wonderful, (1175)
The price is AED 555
AED 775 total
includes taxes & fees
16 Jun - 17 Jun

Hotel Contessa
Hotel Contessa
9.0 out of 10, Wonderful, (3065)
The price is AED 542
AED 697 total
includes taxes & fees
26 May - 27 May

Hyatt Regency San Antonio Riverwalk
Hyatt Regency San Antonio Riverwalk
9.0 out of 10, Wonderful, (1757)
The price is AED 590
AED 827 total
includes taxes & fees
16 Jun - 17 Jun

The Westin Riverwalk, San Antonio
The Westin Riverwalk, San Antonio
8.8 out of 10, Excellent, (1213)
The price is AED 587
AED 699 total
includes taxes & fees
5 Jun - 6 Jun

Hotel Valencia Riverwalk
Hotel Valencia Riverwalk
9.4 out of 10, Exceptional, (1901)
The price is AED 621
AED 812 total
includes taxes & fees
26 May - 27 May

Canopy by Hilton San Antonio Riverwalk
Canopy by Hilton San Antonio Riverwalk
9.4 out of 10, Exceptional, (1503)
The price is AED 774
AED 931 total
includes taxes & fees
25 May - 26 May

Plaza San Antonio Hotel & Spa, Autograph Collection
Plaza San Antonio Hotel & Spa, Autograph Collection
9.2 out of 10, Wonderful, (468)
The price is AED 537
AED 746 total
includes taxes & fees
23 May - 24 May
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Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.

Thompson San Antonio - Riverwalk, by Hyatt
115 Lexington Avenue, San Antonio, TX
The price is AED 840 per night from Jun 1 to Jun 2
AED 840
AED 1,118 total
1 Jun - 2 Jun
includes taxes & fees
9/10 Wonderful! (740 reviews)
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Recent reviews of Medical Center District hotels
Recent reviews of Medical Center District hotels

Riverwalk Plaza
5/5 Excellent
"Everything was great! The only complaint was the ac. I put it on 68 and fan on high and it felt warmer than I would like. "
A verified traveler stayed at Riverwalk Plaza
Posted 14 hours ago
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Medical Center District Hotels by Star Rating
Hotels in Medical Center District Neighborhoods
Stay near popular Medical Center District attractions
- Hotels near USAA Corporate Office Headquarters
- Hotels near South Texas Medical Center
- Hotels near University of Texas Health and Science Center at San Antonio
- Hotels near CHRISTUS Santa Rosa Hospital - Medical Center
- Hotels near Oak Hills Country Club
- Hotels near The San Antonio Art Institute
- Hotels near River Walk
- Hotels near Six Flags Fiesta Texas
- Hotels near Lackland Air Force Base
- Hotels near Alamo
- Hotels near Henry B. González Convention Center
- Hotels near San Antonio Zoo and Aquarium
- Hotels near Alamodome
- Hotels near San Antonio River
- Hotels near Frost Bank Center
- Hotels near The Shops of La Cantera
Explore more hotels
- Hotel Contessa
- La Cantera Resort & Spa
- Days Inn by Wyndham San Antonio Alamo/Riverwalk
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- La Quinta Inn & Suites by Wyndham San Antonio Downtown
- Hyatt Regency Hill Country Resort & Spa
- Omni La Mansion del Rio
- Grand Hyatt San Antonio River Walk
- The Westin Riverwalk, San Antonio
- Hyatt Regency San Antonio Riverwalk
- Canopy by Hilton San Antonio Riverwalk
- La Quinta Inn & Suites by Wyndham San Antonio Airport
- Hilton San Antonio Hill Country
- Crowne Plaza San Antonio Airport by IHG
- JW Marriott San Antonio Hill Country Resort & Spa
- Thompson San Antonio - Riverwalk, by Hyatt
- Hotel Valencia Riverwalk
- Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
- Holiday Inn San Antonio - Riverwalk by IHG
- InterContinental San Antonio Riverwalk by IHG