Find hotels in Defiance, MO from AED 212

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Compare 776 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (670)
"Great location. The room was very spacious and clean. The staff at check-in was friendly. I really enjoyed my stsy. "
The price is AED 437
AED 513 total
includes taxes & fees
17 Nov 2024 - 18 Nov 2024
Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
Baymont by Wyndham Warrenton
2.5 star property
7.2 out of 10, Good, (872)
"The room was clean and comfortable. When dealing with staff they were pleasant."
The price is AED 281
AED 322 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Baymont by Wyndham Warrenton
Quality Inn
2.5 star property
8.2 out of 10, Very Good, (674)
"Very friendly and clean, nice people good value"
The price is AED 294
AED 326 total
includes taxes & fees
19 Nov 2024 - 20 Nov 2024
Quality Inn
Economy Inn Wentzville
2.0 star property
6.4 out of 10, (391)
"Great inexpensive hotel. Comfortable beds and clean shower, its all we needed for a 1 night rest on the way thru. I didn’t see much for food nearby. "
The price is AED 257
AED 285 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Economy Inn Wentzville
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (504)
"Lady at front desk very helpful "
The price is AED 474
AED 530 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
Best Western Plus Washington Hotel
Super 8 by Wyndham Warrenton
2.0 star property
7.4 out of 10, Good, (504)
"Robert was veey nice when we checked in at midnight. He was great at brealfast at 6. Clean, quiet rooom. Wonderful breakfast "
The price is AED 212
AED 238 total
includes taxes & fees
8 Nov 2024 - 9 Nov 2024
Super 8 by Wyndham Warrenton
Hampton Inn St. Louis Wentzville
2.5 star property
9.0 out of 10, Wonderful, (552)
"There was nothing we didn't like. It was a great place to stay for 3 nights in Wentzville, Missouri!"
The price is AED 496
AED 558 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
Hampton Inn St. Louis Wentzville
Fairfield Inn & Suites Wentzville
2.5 star property
9.0 out of 10, Wonderful, (541)
"Very clean rooms and a lot of food options close "
The price is AED 503
AED 568 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
Fairfield Inn & Suites Wentzville
Super 8 by Wyndham Washington
2.0 star property
8.4 out of 10, Very Good, (596)
"We have stayed at a few Super 8's in our travels around this country, they are NOT our first choice by a long shot! but sometimes you don't have any other options, so I was a little Leary booking this one in Washington. MO., again not a lot of options, BUT we were pleasantly surprised! SAFE (no transients), CLEAN, FRIENDLY STAFF AND CONVIENENT to anything around the Washington area. "
The price is AED 297
AED 331 total
includes taxes & fees
25 Nov 2024 - 26 Nov 2024
Super 8 by Wyndham Washington
Holiday Inn Express Warrenton, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (466)
"Clean, comfortable bed, friendly staff."
The price is AED 474
AED 542 total
includes taxes & fees
17 Nov 2024 - 18 Nov 2024
Holiday Inn Express Warrenton, an IHG Hotel
TownePlace Suites by Marriott Wentzville
3.0 star property
9.6 out of 10, Exceptional, (14)
"Very Clean, easy, no problems!"
The price is AED 584
AED 678 total
includes taxes & fees
10 Nov 2024 - 11 Nov 2024
TownePlace Suites by Marriott Wentzville
The Inn at Elijah McLeans
4.0 star property
9.2 out of 10, Wonderful, (98)
"The Inn itself is beautiful with a great view of river. The bed itself was so comfortable, but the pillows were too hard and flat. Would definitely come back!"
The price is AED 496
AED 552 total
includes taxes & fees
4 Nov 2024 - 5 Nov 2024
The Inn at Elijah McLeans
Central Hotel
3.5 star property
9.8 out of 10, Exceptional, (102)
"We really enjoyed our stay. "
The price is AED 569
AED 622 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Central Hotel
Pinckney Bend Bed & Breakfast
3.0 star property
9.4 out of 10, Exceptional, (96)
"Beautiful view and such a relaxing setting! Tricia and Tom were awesome hosts! Breakfast was delicious !"
The price is AED 576
AED 622 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Pinckney Bend Bed & Breakfast
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
2.0 star property
10.0 out of 10, Exceptional, (1)
"Lived the scenery and decor. Hosts were lovely!! Vern nice breakfast!!"
The price is AED 606
AED 717 total
includes taxes & fees
4 Nov 2024 - 5 Nov 2024
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
TheOutPostInn Bed&Breakfast - The Blue Victorian
10.0 out of 10, Exceptional, (3)
"Place was clean "
The price is AED 404
AED 680 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
TheOutPostInn Bed&Breakfast - The Blue Victorian
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
10.0 out of 10, Exceptional, (4)
"Everything was great. The hot breakfast and friendliness of the hosts were great. The view of the Missouri River was breathtaking."
The price is AED 606
AED 725 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
10.0 out of 10, Exceptional, (2)
"Not much available for cooking but we made it work. Boiled crab legs n baked biscuits on the grill! Beautiful weekend with the snow storm and views"
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
TheHistorian! Daniel Boone Country-Marthasville,MO
9.4 out of 10, Exceptional, (11)
"Lovely and comfortable place to stay"
The price is AED 465
AED 754 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
TheHistorian! Daniel Boone Country-Marthasville,MO
Lakefront Studio Condo
2.0 star property
10.0 out of 10, Exceptional, (6)
"Very cute condo it maximizes the space well, in addition the view is awesome! Highly recommend to anyone thinking of staying here"
The price is AED 459
AED 963 total
includes taxes & fees
3 Nov 2024 - 4 Nov 2024
Lakefront Studio Condo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Sonesta ES Suites St. Louis - Chesterfield and La Quinta Inn & Suites by Wyndham St. Louis Westport. See all available top hotels, or vacation rentals in Defiance.

What's the top vacation rental in Defiance?

The St. Charles Guest House, lovely historic home, fun for families and groups: Visitors like this Defiance vacation home rental. It is located on a river and offers a fireplace, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?

Sonesta ES Suites St. Louis - Chesterfield: Offers daily, a seasonal outdoor pool, and free self parking. La Quinta Inn & Suites by Wyndham St. Louis Westport and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium, and Gateway Arch. In Defiance, there are 18 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at Missouri River, August A. Busch Memorial Conservation Area, and Broemmelsiek Park. A couple of additional sights to add to your agenda are Chandler Hill Vineyards and Sugar Creek Winery. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.