Find hotels in Defiance, MO from AED 219

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Compare 809 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Crowne Plaza St. Louis Airport by IHG

3.5 star property
8.0 out of 10, Very Good, (1121)
"No"
The price is AED 506
AED 599 total
includes taxes & fees
18 Apr - 19 Apr
Crowne Plaza St. Louis Airport by IHG

MainStay Suites St Louis Airport

3.0 star property
8.2 out of 10, Very Good, (273)
"Will stay again"
The price is AED 354
AED 422 total
includes taxes & fees
1 Apr - 2 Apr
MainStay Suites St Louis Airport

Comfort Inn St Louis – Airport

3.0 star property
8.4 out of 10, Very Good, (806)
"The guy at the desk was very friendly and pleasant to deal with and the accommodations were good!"
The price is AED 311
AED 372 total
includes taxes & fees
6 Apr - 7 Apr
Comfort Inn St Louis – Airport

Embassy Suites by Hilton St. Louis Airport

3.5 star property
7.6 out of 10, Good, (1045)
"The room was nice, and the floor was quiet "
The price is AED 536
AED 634 total
includes taxes & fees
19 Apr - 20 Apr
Embassy Suites by Hilton St. Louis Airport

Extended Stay America Select Suites - St. Louis - Airport - Central

2.5 star property
7.0 out of 10, Good, (921)
"Their staff is exceptional. Especially Jazz."
The price is AED 288
AED 345 total
includes taxes & fees
1 Apr - 2 Apr
Extended Stay America Select Suites - St. Louis - Airport - Central

Hilton St. Louis Frontenac

4.0 star property
8.8 out of 10, Excellent, (1061)
"Great hotel, great area, nice and quiet. "
The price is AED 528
AED 615 total
includes taxes & fees
6 Apr - 7 Apr
Hilton St. Louis Frontenac

La Quinta Inn & Suites by Wyndham St. Louis Westport

3.0 star property
7.2 out of 10, Good, (1185)
"Good staff"
The price is AED 324
AED 376 total
includes taxes & fees
20 Apr - 21 Apr
La Quinta Inn & Suites by Wyndham St. Louis Westport

Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

2.5 star property
5.8 out of 10, (1063)
"Not Applicable"
The price is AED 241
AED 280 total
includes taxes & fees
5 Apr - 6 Apr
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

Red Roof Inn St Louis - Westport/ Maryland Heights

2.0 star property
5.4 out of 10, (1028)
"Nice staff and clean beds, quick check in, will come back again in the future"
The price is AED 241
AED 279 total
includes taxes & fees
3 Apr - 4 Apr
Red Roof Inn St Louis - Westport/ Maryland Heights

The Lodge Hotel and Banquets

2.0 star property
4.6 out of 10, (303)
"Hotel is under renovation rooms could definitely use some updating pool & hot tub was a little chilly overall stay was good & we hope to return after the renovations have been done! "
The price is AED 237
AED 286 total
includes taxes & fees
7 Apr - 8 Apr
The Lodge Hotel and Banquets

Courtyard by Marriott St Louis Westport Plaza

3.0 star property
8.8 out of 10, Excellent, (1060)
"My room was clean. A clean room means everything. "
The price is AED 393
AED 456 total
includes taxes & fees
18 Apr - 19 Apr
Courtyard by Marriott St Louis Westport Plaza

Residence Inn St Louis Westport

3.0 star property
9.2 out of 10, Wonderful, (407)
"Na"
The price is AED 526
AED 610 total
includes taxes & fees
6 Apr - 7 Apr
Residence Inn St Louis Westport

Fairfield Inn & Suites St Louis Westport

2.5 star property
9.2 out of 10, Wonderful, (767)
"Outstanding property in every way. Great location in entertainment district atvWestportPaza. Breakfast service by Traran included her walking next door to sister property to get us two biscuits to enjoy for breakfast. "
The price is AED 493
AED 571 total
includes taxes & fees
6 Apr - 7 Apr
Fairfield Inn & Suites St Louis Westport

Extended Stay America Select Suites St Louis Westport Craig

2.5 star property
6.4 out of 10, (738)
"Good"
The price is AED 248
AED 288 total
includes taxes & fees
1 May - 2 May
Extended Stay America Select Suites St Louis Westport Craig

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 star property
4.8 out of 10, (1175)
"helpful and chill"
The price is AED 219
AED 253 total
includes taxes & fees
6 Apr - 7 Apr
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Courtyard by Marriott St Louis Creve Coeur

3.0 star property
8.6 out of 10, Excellent, (1056)
"Cleanest hotel I’ve stayed in in a long time. Comfortable. I think they have done a remodeling throughout. Highly recommend. "
The price is AED 372
AED 432 total
includes taxes & fees
18 Apr - 19 Apr
Courtyard by Marriott St Louis Creve Coeur

Comfort Inn St. Louis - Westport Event Center

3.0 star property
7.2 out of 10, Good, (1052)
"Clean room and nice staff "
The price is AED 324
AED 376 total
includes taxes & fees
20 Apr - 21 Apr
Comfort Inn St. Louis - Westport Event Center

Best Western Plus St. Louis West-Westport

2.5 star property
8.2 out of 10, Very Good, (1145)
"No drinking water spout."
The price is AED 327
AED 380 total
includes taxes & fees
6 Apr - 7 Apr
Best Western Plus St. Louis West-Westport

Hampton Inn St. Louis/Westport

2.5 star property
7.8 out of 10, Good, (929)
"There was a mixup on my reservation, but they made it right. It was a clean and up-to-date facility. My major complaint is they offer 138 TV stations, but no guide or instructions on how to access the channel you want. The channels were two numbers followed by a dash, followed by another number. Most of us do not know how to input those stations. A simple card in the room with instructions would have made the experience so much better."
The price is AED 325
AED 377 total
includes taxes & fees
18 Apr - 19 Apr
Hampton Inn St. Louis/Westport

Sheraton Westport Plaza Hotel St. Louis

3.5 star property
8.4 out of 10, Very Good, (833)
"Choice checked us in and was absolutely amazing in handling an issue we had. "
The price is AED 465
AED 551 total
includes taxes & fees
18 Apr - 19 Apr
Sheraton Westport Plaza Hotel St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Defiance

Trip time! Discover the wineries, parks, and history in Defiance.

Frequently asked questions

What's the best place to stay in Defiance?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Sonesta ES Suites St. Louis - Chesterfield and Hollywood Casino & Hotel St. Louis. See all available top hotels, or vacation rentals in Defiance.

What's the top vacation rental in Defiance?

☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome: Visitors like this Defiance vacation home rental. It is located on a river and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a private yard and a selection of games. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool, and buffet. Sonesta ES Suites St. Louis - Chesterfield and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium, and Gateway Arch. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area, and Missouri River. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.