Find hotels in Defiance, MO from AED 212

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Compare 828 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (676)
"Friendly, courteous staff, and good breakfast. "
The price is AED 424
AED 498 total
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel

Baymont by Wyndham Warrenton

2.5 star property
7.2 out of 10, Good, (879)
"Friendly staff . quick check in , clean , good breakfast (many choices)."
The price is AED 281
AED 315 total
includes taxes & fees
1 Dec - 2 Dec
Baymont by Wyndham Warrenton

Quality Inn

2.5 star property
8.2 out of 10, Very Good, (682)
"Very friendly and clean, nice people good value"
The price is AED 294
AED 326 total
includes taxes & fees
22 Dec - 23 Dec
Quality Inn

Economy Inn Wentzville

2.0 star property
6.4 out of 10, (394)
"All good "
The price is AED 257
AED 285 total
includes taxes & fees
26 Nov - 27 Nov
Economy Inn Wentzville

Best Western Plus Washington Hotel

2.5 star property
9.0 out of 10, Wonderful, (507)
"The staff were very friendly, professional and helpful at check in. We are meeting up with other family members and the staff went out of their way to accommodate our group."
The price is AED 474
AED 530 total
includes taxes & fees
26 Nov - 27 Nov
Best Western Plus Washington Hotel

Super 8 by Wyndham Warrenton

2.0 star property
7.4 out of 10, Good, (507)
"We stayed on the weekend of Diwali (the beginning of the Hindu fiscal year), so we understood the hotel was short staffed due to the celebration. On our 3rd attempt at a clean room, we got one. The woman working at check in was very kind. Later that evening when we returned, our TV didn't work. Another lady at the front desk came up and called the owner who walked her through fixing it. The room was clean, the beds were comfortable, and we slept well. The next morning my biggest issue was there...
The price is AED 212
AED 238 total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Warrenton

Hampton Inn St. Louis Wentzville

2.5 star property
9.0 out of 10, Wonderful, (554)
"Very easy check in process. A lot of the parking was in front of the hotel which in my opinion is amazing. The young lady I dealt with during check in was very friendly and easy to work with. "
The price is AED 496
AED 558 total
includes taxes & fees
1 Dec - 2 Dec
Hampton Inn St. Louis Wentzville

Fairfield Inn & Suites Wentzville

2.5 star property
9.0 out of 10, Wonderful, (542)
"The staff was very helpful. I had a family emergency and couldn't stay the following night. Booked through Expedia but the front desk person was helping me to resolve the issue."
The price is AED 503
AED 568 total
includes taxes & fees
1 Dec - 2 Dec
Fairfield Inn & Suites Wentzville

TownePlace Suites by Marriott Wentzville

3.0 star property
9.6 out of 10, Exceptional, (16)
"Very relaxing, clean, inviting, quiet and the staff were awesome!! Thank you!"
The price is AED 584
AED 678 total
includes taxes & fees
1 Dec - 2 Dec
TownePlace Suites by Marriott Wentzville

Holiday Inn Express Warrenton, an IHG Hotel

2.5 star property
9.2 out of 10, Wonderful, (471)
"Great location, friendly staff, quiet room, clean and comfortable bed. Hot, delicious breakfast."
The price is AED 409
AED 460 total
includes taxes & fees
27 Nov - 28 Nov
Holiday Inn Express Warrenton, an IHG Hotel

Super 8 by Wyndham Washington

2.0 star property
8.4 out of 10, Very Good, (598)
"Weird key issue- they stopped working when we went to breakfast. We didn’t check out yet but the card keys stopped working. Our friends had the same issue. "
The price is AED 311
AED 347 total
includes taxes & fees
2 Dec - 3 Dec
Super 8 by Wyndham Washington

The Inn at Elijah McLeans

4.0 star property
9.2 out of 10, Wonderful, (99)
"Very clean and customer service was great. We needed an early check in and they made it happen for us!"
The price is AED 523
AED 586 total
includes taxes & fees
26 Nov - 27 Nov
The Inn at Elijah McLeans

Central Hotel

3.5 star property
9.8 out of 10, Exceptional, (102)
"We really enjoyed our stay. "
The price is AED 569
AED 622 total
includes taxes & fees
26 Nov - 27 Nov
Central Hotel

Pinckney Bend Bed & Breakfast

3.0 star property
9.6 out of 10, Exceptional, (98)
"The breakfast was wonderful and view was tremendous. "
The price is AED 539
AED 585 total
includes taxes & fees
2 Dec - 3 Dec
Pinckney Bend Bed & Breakfast

TheOutPostInn Bed&Breakfast - The Blue Victorian

10.0 out of 10, Exceptional, (3)
"Place was clean "
The price is AED 404
AED 676 total
includes taxes & fees
26 Nov - 27 Nov
TheOutPostInn Bed&Breakfast - The Blue Victorian

Wine Haus: charming cottage with breathtaking views of the Missouri River!!

2.0 star property
10.0 out of 10, Exceptional, (1)
"Lived the scenery and decor. Hosts were lovely!! Vern nice breakfast!!"
The price is AED 606
AED 710 total
includes taxes & fees
27 Nov - 28 Nov
Wine Haus: charming cottage with breathtaking views of the Missouri River!!

Lakefront Studio Condo

2.0 star property
10.0 out of 10, Exceptional, (6)
"Very cute condo it maximizes the space well, in addition the view is awesome! Highly recommend to anyone thinking of staying here"
The price is AED 459
AED 963 total
includes taxes & fees
26 Nov - 27 Nov
Lakefront Studio Condo

Private entry, lower area only with gameRoom, living room, bedroom and bathroom.

10.0 out of 10, Exceptional, (2)
"Not much available for cooking but we made it work. Boiled crab legs n baked biscuits on the grill! Beautiful weekend with the snow storm and views"
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.

TheOutPostInn Bed&Breakfast - The Purple Victorian

6.0 out of 10, (1)
"It was a small room and had to squeeze between the bed and wall to get in. Almost had to use the foot stool to get in the bed secondary to being so high up and the mattress was extremely firm. The pillows were super soft which did not go with the firm bed, woke up several times in the night to re fluff the pillows and still woke up with a sore neck. The thing that bothered me the most was the curtain in the bathroom was screwed to the wall and you could not close them for privacy. The building...
The price is AED 465
AED 743 total
includes taxes & fees
26 Nov - 27 Nov
TheOutPostInn Bed&Breakfast - The Purple Victorian

Studio Condo on the Water @ Innsbrook

9.8 out of 10, Exceptional, (6)
"This was a super cute condo that was clean and comfortable. The furniture was generally very comfortable. The bed is on the firmer side but still comfortable. The bed is high up if that is an issue for anyone. The instructions for checkout were clearly labeled on the door. The door code was sent over timely for check in. I would stay here again. "
The price is AED 367
AED 801 total
includes taxes & fees
26 Nov - 27 Nov
Studio Condo on the Water @ Innsbrook
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are La Quinta Inn & Suites by Wyndham St. Louis Westport and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham. See all available top hotels, or vacation rentals in Defiance.

What's the top vacation rental in Defiance?

The robin nest a cozy cottage on historic main street; pet Friendly: You might want to consider this vacation home rental near Defiance, which is equipped with a selection of games, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?

La Quinta Inn & Suites by Wyndham St. Louis Westport: Offers free self parking, an outdoor pool, and complimentary wireless internet access. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station and Enterprise Center. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Broemmelsiek Park, and Missouri River. A couple of additional sights to add to your agenda are Chandler Hill Vineyards and Sugar Creek Winery. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.