Find hotels in Defiance, MO from AED 219
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Compare 809 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Crowne Plaza St. Louis Airport by IHG
Crowne Plaza St. Louis Airport by IHG
8.0 out of 10, Very Good, (1121)
The price is AED 506
AED 599 total
includes taxes & fees
18 Apr - 19 Apr

MainStay Suites St Louis Airport
MainStay Suites St Louis Airport
8.2 out of 10, Very Good, (273)
The price is AED 354
AED 422 total
includes taxes & fees
1 Apr - 2 Apr

Comfort Inn St Louis – Airport
Comfort Inn St Louis – Airport
8.4 out of 10, Very Good, (806)
The price is AED 311
AED 372 total
includes taxes & fees
6 Apr - 7 Apr

Embassy Suites by Hilton St. Louis Airport
Embassy Suites by Hilton St. Louis Airport
7.6 out of 10, Good, (1045)
The price is AED 536
AED 634 total
includes taxes & fees
19 Apr - 20 Apr

Extended Stay America Select Suites - St. Louis - Airport - Central
Extended Stay America Select Suites - St. Louis - Airport - Central
7.0 out of 10, Good, (921)
The price is AED 288
AED 345 total
includes taxes & fees
1 Apr - 2 Apr

Hilton St. Louis Frontenac
Hilton St. Louis Frontenac
8.8 out of 10, Excellent, (1061)
The price is AED 528
AED 615 total
includes taxes & fees
6 Apr - 7 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Defiance
Trip time! Discover the wineries, parks, and history in Defiance.

More cheap stays in Defiance
More cheap stays in Defiance

Best Western Plus St. Louis West-Westport
12220 Dorsett Rd, Maryland Heights, MO
The price is AED 327 per night from Apr 6 to Apr 7
AED 327
AED 380 total
includes taxes & fees
6 Apr - 7 Apr
8/10 Very Good! (1,006 reviews)
Hotels in Defiance with star-rating
Hotels in Defiance with star-rating

4 Star Hotels
7 properties
Stay near popular Defiance attractions
Stay near popular Defiance attractions

Busch Stadium
4.5/5(1,469 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Recent reviews of Defiance hotels
Recent reviews of Defiance hotels

Ameristar Casino Resort and Spa
5/5 Excellent
"Property beautiful wonder stay "
A verified traveler stayed at Ameristar Casino Resort and Spa
Posted 23 hours ago
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Stay near popular Defiance attractions
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Six Flags St. Louis
- Hotels near Ameristar Casino St. Charles
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Mississippi River
- Hotels near Westport Plaza
- Hotels near St Charles Convention Center
- Hotels near Hollywood Casino
- Hotels near Purina Farms
- Hotels near Magic House - St. Louis Children's Museum
- Hotels near Lindenwood University
- Hotels near Route 66 State Park
- Hotels near Missouri River
- Hotels near Family Arena
- Hotels near Historic Main Street
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Hotels near Defiance Airports
Defiance Hotels by Brand
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Explore more hotels
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- Holiday Inn St. Louis West Six Flags by IHG
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