Find all hotels by Drury Inn & Suites in Defiance, MO from AED 404
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Compare rooms and suites by Drury Inn & Suites in Defiance with rates, reviews, and availability. Most hotels are fully refundable.
Recent reviews of Defiance hotels
Recent reviews of Defiance hotels
5/5 Excellent
Great find
"We were on a 2 week road trip and this was by far the best hotel we stayed at with friendly service, clean room, very comfortable bed, incredible breakfast with biscuits and sausage gravy, scrambled eggs, sausage, etc. We would definitely stay here again! "
A verified traveler stayed at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Posted 18 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Defiance Hotels by Brand
Hotels near popular St. Louis Attractions
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Ameristar Casino St. Charles
- Hotels near Six Flags St. Louis
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Mississippi River
More Accommodation Types in Defiance
Explore more hotels
- Drury Plaza Hotel St. Louis Chesterfield
- Best Western Plus The Charles Hotel
- 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
- Embassy Suites by Hilton St. Louis St. Charles
- Country Inn & Suites by Radisson, St. Charles, MO
- Comfort Inn St Louis – Airport
- Best Western Plus St. Louis West-Westport
- Elimwood Hotel, A Ramada by Wyndham
- Drury Inn & Suites St. Louis Creve Coeur
- Hyatt Place St. Louis/Chesterfield
- Courtyard by Marriott St Louis Westport Plaza
- Holiday Inn Express & Suites St. Louis West - Fenton, an IHG Hotel
- Country Inn & Suites by Radisson, St. Peters, MO
- DoubleTree by Hilton Hotel St. Louis - Chesterfield
- Drury Plaza Hotel St. Louis St. Charles
- Hampton Inn St. Charles St. Peters
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Courtyard by Marriott St Louis Creve Coeur
- DoubleTree by Hilton St. Louis - Westport
- Holiday Inn St. Louis West Six Flags, an IHG Hotel