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Compare 88 Apartments in Defiance with updated reviews, rates, and availability.

The Lofts of North Main Street
Dining
The Lofts of North Main Street
9.6 out of 10, Exceptional, (111)
"Great location"
The price is AED 474
AED 980 total
includes taxes & fees
5 Nov 2024 - 6 Nov 2024
The Lofts of North Main Street
Remodeled Kirkwood Guest house
Patio/fire pit area
Remodeled Kirkwood Guest house
10.0 out of 10, Exceptional, (67)
"Nice family neighborhood, very quiet, rental is immaculate clean and looks new. We will be back. "
Remodeled Kirkwood Guest house
Main Street Balcony Apartment!
Living Space
Main Street Balcony Apartment!
9.6 out of 10, Exceptional, (23)
"My stay was enjoyable and everything was there that was needed. Thank you for a great stay."
Main Street Balcony Apartment!
The Historic Bricks on Main
The Historic Bricks on Main
10.0 out of 10, Exceptional, (6)
"Loved the property and location. Able to walk to all the shops, restaurants, bars etc. "
The Historic Bricks on Main
Zia New Haven
Living area
Zia New Haven
3.5 star property
9.6 out of 10, Exceptional, (5)
"We absolutely loved our stay. Laura was great!"
Zia New Haven
Sunny SparkingClean King bed Apt- CreveCoeurPark
Private kitchen
Sunny SparkingClean King bed Apt- CreveCoeurPark
9.6 out of 10, Exceptional, (9)
"Once booked the site listed the wrong address (transposed numbers). We guessed which house becausewe had seen the photos. Arrived 10 minutes before check in and the amazing cleaning person confirmed we were in the right place and gave us the access codes. The house was spotless and beautifully adorned. Neighborhood a bit run down so it was suprising to see such a lovely interior as seen on the photos online. Communication with host was automated and as mentioned, the house numbers were reversed...
The price is AED 349
AED 793 total
includes taxes & fees
11 Nov 2024 - 12 Nov 2024
Sunny SparkingClean King bed Apt- CreveCoeurPark
Duplex Hideaway in St. Charles, MO
Fully Equipped Kitchen
Duplex Hideaway in St. Charles, MO
10.0 out of 10, Exceptional, (4)
"The house is cute. Street parking only. Clean but small. The neighborhood was fantastic. In a historical district. Close to many shops, restaurants, and a river side park. Great place to stay with a dog."
Duplex Hideaway in St. Charles, MO
'The Ruebling House': Bright, Modern, & Renovated!
Defiance Vacation Rental | 2BR | 1BA | 1,100 Sq Ft | Steps Required
'The Ruebling House': Bright, Modern, & Renovated!
9.6 out of 10, Exceptional, (15)
"The property was wonderful for a family traveling for Christmas. The host even had Christmas trees in both rentals."
'The Ruebling House': Bright, Modern, & Renovated!
Adorable furnished apartment with ALL the amenities!
Living area
Adorable furnished apartment with ALL the amenities!
9.8 out of 10, Exceptional, (12)
"Accommodations with two large bedrooms and two full bathrooms separated by living space was the perfect place for a weekend girls getaway. Easy to find, quiet and close to the downtown shopping district. If you are okay climbing stairs to get to the apartment, it is definitely worth it."
Adorable furnished apartment with ALL the amenities!
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Room
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
2.0 star property
7.4 out of 10, Good, (3)
"Really convenient spot for my family, who stayed at this property for a week. Owner was very responsive to everything and made our experience very pleasant. Very pet friendly. Everything was great...only (minor) downside was that the WiFi reception was very spotty. Combined with poor cell reception in the general area, I had to go outside at times to get data. Would definitely stay here again next time we're in town. "
The price is AED 275
AED 533 total
includes taxes & fees
7 Nov 2024 - 8 Nov 2024
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
The Wild West Getaway- 204-1
Room
The Wild West Getaway- 204-1
10.0 out of 10, Exceptional, (2)
"Overall, we loved this space! It's been wonderfully renovated, and has a great view of main street out the front, and the river out the back! In the winter especially you'd be able to see the river even better once the leaves are down. It was very clean. Both beds were extremely comfortable, and the shower was super nice. Be aware that the space is above a bar, so you will hear music loud and clear on nights where they have it, which was both nights we were there (Friday and Saturday), which...
The Wild West Getaway- 204-1
New Melle Apartment Near Missouri Wine Country
New Melle Vacation Rental | 1BR | 1BA | 1,300 Sq Ft | Stairs Required
New Melle Apartment Near Missouri Wine Country
9.4 out of 10, Exceptional, (3)
"Super quiet and comfortable. Would go back"
New Melle Apartment Near Missouri Wine Country
1st Capitol Mansion - Suite 401
1st Capitol Mansion - Suite 401
9.0 out of 10, Wonderful, (6)
"The condo is very spacious, with plenty of beds. There are some really cool historic features in the building. Great location. And the host, John, was very helpful."
The price is AED 422
AED 1,010 total
includes taxes & fees
1 Dec 2024 - 2 Dec 2024
1st Capitol Mansion - Suite 401
Prime Loft of Main Street
Living area
Prime Loft of Main Street
9.8 out of 10, Exceptional, (79)
"Loved shopping the old historic street with fun shops and farmer’s market on Saturday morning. Lots of helpful touches, like blackout curtains to the street. It was stated that there was street noise from the coffee shop but it lasted til about midnight on Friday. Burned out light bulbs in main level bathroom made it hard for 5 adults to get ready for a wedding. So glad there was a second bathroom with adequate lighting. Reading lights in bedroom could not be used because cords were missing....
The price is AED 474
AED 980 total
includes taxes & fees
11 Nov 2024 - 12 Nov 2024
Prime Loft of Main Street
Spacious 2-Bedroom Abode Just Moments from Main Street
Kitchen
Spacious 2-Bedroom Abode Just Moments from Main Street
8.6 out of 10, Excellent, (10)
"My babe and I came to St Charles for a recon trip ahead of our family’s move this summer. We didn’t spend much time in the apartment, but it was sufficient for our needs."
Spacious 2-Bedroom Abode Just Moments from Main Street
Stay on Historic Main!
Bed and couch
Stay on Historic Main!
9.2 out of 10, Wonderful, (22)
"Everything was as listed. Cute little studio apartment & would definitely book again. Host was super responsive."
Stay on Historic Main!
Private Basement Retreat with a HOT TUB
Bedroom
Private Basement Retreat with a HOT TUB
7.4 out of 10, Good, (3)
"We had a perfect stay! Loved the overall look and feel of this place. Very comfortable! Stocked well. Beds were great! Location was perfect for our needs. A little shopping in St Peters Mid Rivers area 10 min away and shopping and dinner in St Charles on main street! Also only 10 min away! We will return if available for future visits!"
The price is AED 298
AED 903 total
includes taxes & fees
5 Nov 2024 - 6 Nov 2024
Private Basement Retreat with a HOT TUB
Amazing Renovated Historic Loft on Main Street
Room
Amazing Renovated Historic Loft on Main Street
10.0 out of 10, Exceptional, (48)
"Perfect location! Right on Main St. Wonderful coffee shop on the corner. I went with my aunt and uncle. I stayed in the loft which had its own bathroom! Worked perfectly! "
The price is AED 474
AED 980 total
includes taxes & fees
5 Nov 2024 - 6 Nov 2024
Amazing Renovated Historic Loft on Main Street
Main Street Living! 2 Bedroom Unit right On Main!
View of the Historic Building from Main Street. This rental unit is upstairs above the commercial units located on Historic Main Street
Main Street Living! 2 Bedroom Unit right On Main!
10.0 out of 10, Exceptional, (19)
"The property was clean and nicely stocked with everything my wife and I needed for a comfortable stay. We brought our two soft coated wheaten terrier dogs. The property listed as pet friendly, and we didn’t experience any pet hair. St. Charles Main Street if very dog friendly. "
Main Street Living! 2 Bedroom Unit right On Main!
Lovely Couples Escape on Mississippi River!
St Charles Vacation Rental | Studio | 1BA | 536 Sq Ft | Stairs Required to Enter
Lovely Couples Escape on Mississippi River!
10.0 out of 10, Exceptional, (12)
"Perfect. Very cozy little place. Had a wonderful stay here and it was a very quiet and relaxing location. Great communication. Would definitely stay here again."
Lovely Couples Escape on Mississippi River!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Defiance

BACKYARD OASIS! Cozy and charming 60s Brick ranch with relaxing gazebo over pond
Exterior
BACKYARD OASIS! Cozy and charming 60s Brick ranch with relaxing gazebo over pond
9.8 out of 10, Exceptional, (25)
"Great place "
BACKYARD OASIS! Cozy and charming 60s Brick ranch with relaxing gazebo over pond
The St. Charles Guest House, lovely historic home, fun for families and groups
Lovely master bedroom with fireplace and sitting area.
The St. Charles Guest House, lovely historic home, fun for families and groups
10.0 out of 10, Exceptional, (118)
"We loved this place and the location! We plan on returning one day!"
The St. Charles Guest House, lovely historic home, fun for families and groups
Craigshire Suites
Room
Craigshire Suites
3.0 star property
7.0 out of 10, Good, (1110)
"Great customer service "
The price is AED 294
AED 633 total
includes taxes & fees
5 Nov 2024 - 6 Nov 2024
Craigshire Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You’ll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Situated in St. Charles, 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, sofa beds, and Smart TVs. Amazing Renovated Historic Loft on Main Street: Located 19.2 mi/30.8 km away in St. Charles. Free WiFi and Smart TVs are included. Remodeled Kirkwood Guest house: It’s situated in Kirkwood, 20 mi/32.2 km away. Includes private balconies, sofa beds, and Smart TVs. 1st Capitol Mansion - Suite 401: 18.7 mi/30.1 km away in St. Charles. Cheerful 1-bedroom whitin residential home with free parking: It’s located in Troy, 23.9 mi/38.5 km from Defiance. Includes free WiFi.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you’re planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
Missouri River and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you’d like to explore around the area, you may want a rental car for your journey.