Find all hotels by Independent in Defiance, MO from AED68
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Compare rooms and suites by Independent in Defiance with rates, reviews, and availability. Most hotels are fully refundable.
Recent reviews of Defiance hotels
Recent reviews of Defiance hotels
5/5 Excellent
"Hotel was clean and staff was friendly. Also enjoyed the fact it was in walkable distance to a sports bar where we were able to catch a few games."
A verified traveler from Smithville stayed at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Posted 14 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Defiance Hotels by Brand
Hotels near popular St. Louis Attractions
- Hotels near Chandler Hill Vineyards
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Broemmelsiek Park
- Hotels near Yellow Farmhouse Winery
- Hotels near Six Flags St. Louis
- Hotels near Ameristar Casino St. Charles
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Mississippi River
More Accommodation Types in Defiance
Explore more hotels
- Wingate by Wyndham St. Louis/Fenton Route 66
- Embassy Suites by Hilton St. Louis St. Charles
- Country Inn & Suites by Radisson, St. Charles, MO
- Hyatt Place St. Louis/Chesterfield
- Drury Plaza Hotel St. Louis St. Charles
- Comfort Inn St Louis – Airport
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Best Western Plus St. Louis West-Westport
- Drury Inn & Suites St. Louis Creve Coeur
- Drury Inn & Suites Southwest St. Louis
- Elimwood Hotel, A Ramada by Wyndham
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- DoubleTree by Hilton Hotel St. Louis - Chesterfield
- Hilton St. Louis Frontenac
- Courtyard by Marriott St Louis Westport Plaza
- Hampton Inn St. Charles St. Peters
- Country Inn & Suites by Radisson, St. Peters, MO
- Comfort Inn & Suites St. Louis - O'Fallon
- Best Western Plus The Charles Hotel
- Holiday Inn St. Louis - Creve Coeur, an IHG Hotel