Find all hotels by Independent in Defiance, MO from AED 231
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Compare rooms and suites by Independent in Defiance with rates, reviews, and availability. Most hotels are fully refundable.

The Wildwood Hotel
The Wildwood Hotel
9.0 out of 10, Wonderful, (1481)
The price is AED 324
AED 392 total
includes taxes & fees
5 May - 6 May

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (834)
The price is AED 231
AED 266 total
includes taxes & fees
25 Apr - 26 Apr

The Lodge Hotel and Banquets
The Lodge Hotel and Banquets
4.8 out of 10, (314)
The price is AED 252
AED 303 total
includes taxes & fees
25 Apr - 26 Apr

River Sirens Hotel
River Sirens Hotel
9.8 out of 10, Exceptional, (138)
The price is AED 433
AED 493 total
includes taxes & fees
27 Apr - 28 Apr

Economy Inn Wentzville
Economy Inn Wentzville
6.4 out of 10, (415)
The price is AED 257
AED 292 total
includes taxes & fees
25 Apr - 26 Apr

Research Park Inn St Louis West – Chesterfield
Research Park Inn St Louis West – Chesterfield
5.8 out of 10, (1006)

The Inn at Elijah McLeans
The Inn at Elijah McLeans
9.2 out of 10, Wonderful, (109)
The price is AED 496
AED 565 total
includes taxes & fees
11 May - 12 May

Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
10.0 out of 10, Exceptional, (27)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent reviews of Defiance hotels
Recent reviews of Defiance hotels

Drury Plaza Hotel St. Louis St. Charles
5/5 Excellent
"Everything was great."
A verified traveler stayed at Drury Plaza Hotel St. Louis St. Charles
Posted 1 day ago
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Defiance Hotels by Brand
Hotels near popular St. Louis Attractions
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Chandler Hill Vineyards
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Sugar Creek Winery
- Hotels near Broemmelsiek Park
- Hotels near Yellow Farmhouse Winery
- Hotels near Six Flags St. Louis
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Ameristar Casino St. Charles
- Hotels near Mississippi River
More Accommodation Types in Defiance
Explore more hotels
- Drury Plaza Hotel St. Louis Chesterfield
- Baymont by Wyndham St. Charles
- Best Western Plus St. Louis West-Westport
- Holiday Inn St. Louis - Creve Coeur by IHG
- Hampton Inn St. Charles St. Peters
- Courtyard by Marriott St Louis Westport Plaza
- Embassy Suites by Hilton St. Louis St. Charles
- Drury Inn & Suites Southwest St. Louis
- Holiday Inn St. Louis West Six Flags by IHG
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Relax Inn Saint Charles
- Country Inn & Suites by Radisson, St. Peters, MO
- Hilton St. Louis Frontenac
- Drury Inn & Suites St. Louis St. Peters
- Courtyard by Marriott St Louis Creve Coeur
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Country Inn & Suites by Radisson, St. Charles Historic District
- Comfort Suites St Charles - St Louis
- Holiday Inn Express St. Louis West - O'Fallon by IHG
- DoubleTree by Hilton St. Louis - Westport