Find all hotels by Independent in Defiance, MO from AED 231
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Compare rooms and suites by Independent in Defiance with rates, reviews, and availability. Most hotels are fully refundable.

The Wildwood Hotel
The Wildwood Hotel
9.0 out of 10, Wonderful, (1619)
The price is AED 324
AED 392 total
includes taxes & fees
8 Apr - 9 Apr

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (805)
The price is AED 231
AED 266 total
includes taxes & fees
2 Apr - 3 Apr

The Lodge Hotel and Banquets
The Lodge Hotel and Banquets
4.6 out of 10, (303)
The price is AED 237
AED 286 total
includes taxes & fees
7 Apr - 8 Apr

River Sirens Hotel
River Sirens Hotel
10.0 out of 10, Exceptional, (135)
The price is AED 528
AED 601 total
includes taxes & fees
6 Apr - 7 Apr

Economy Inn Wentzville
Economy Inn Wentzville
6.4 out of 10, (409)
The price is AED 257
AED 292 total
includes taxes & fees
2 Apr - 3 Apr

Research Park Inn St Louis West – Chesterfield
Research Park Inn St Louis West – Chesterfield
5.8 out of 10, (1006)

The Inn at Elijah McLeans
The Inn at Elijah McLeans
9.0 out of 10, Wonderful, (107)
The price is AED 496
AED 565 total
includes taxes & fees
15 Apr - 16 Apr

Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
10.0 out of 10, Exceptional, (25)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent reviews of Defiance hotels
Recent reviews of Defiance hotels

Baymont by Wyndham St. Charles
5/5 Excellent
"Friendly staff, great breakfast and clean"
A verified traveler stayed at Baymont by Wyndham St. Charles
Posted 18 hours ago
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Defiance Hotels by Brand
Hotels near popular St. Louis Attractions
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Six Flags St. Louis
- Hotels near Ameristar Casino St. Charles
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Mississippi River
More Accommodation Types in Defiance
Explore more hotels
- Drury Plaza Hotel St. Louis St. Charles
- Best Western Plus St. Louis West-Westport
- Crowne Plaza St. Louis Airport by IHG
- Drury Plaza Hotel St. Louis Chesterfield
- Holiday Inn St. Louis - Creve Coeur by IHG
- Embassy Suites by Hilton St. Louis St. Charles
- Courtyard by Marriott St Louis Westport Plaza
- Holiday Inn St. Louis West Six Flags by IHG
- Hampton Inn St. Charles St. Peters
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Country Inn & Suites by Radisson, St. Charles Historic District
- Holiday Inn Express St. Louis West - O'Fallon by IHG
- Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
- Hilton St. Louis Frontenac
- DoubleTree by Hilton Hotel St. Louis - Chesterfield
- Courtyard by Marriott St Louis Creve Coeur
- Drury Inn & Suites Southwest St. Louis
- Relax Inn Saint Charles
- Comfort Suites St Charles - St Louis
- Comfort Inn St Louis – Airport