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Check prices for these dates

Next weekend
16 May - 18 May
In two weeks
23 May - 25 May
In one month
6 Jun - 8 Jun
In two months
4 Jul - 6 Jul

Compare 11 B&B in Defiance with updated reviews, rates, and availability.

Pinckney Bend Bed & Breakfast
Property grounds

Pinckney Bend Bed & Breakfast

3.0 star property
9.6 out of 10, Exceptional, (105)
"Pretty view. Great hospitality "
The price is AED 606
AED 662 total
includes taxes & fees
7 May - 8 May
Pinckney Bend Bed & Breakfast
Central Hotel
Front of property

Central Hotel

3.5 star property
9.8 out of 10, Exceptional, (104)
"We really enjoyed our stay. "
The price is AED 569
AED 622 total
includes taxes & fees
9 May - 10 May
Central Hotel
The Daniel Boone Room -Marthasville,MO
Interior

The Daniel Boone Room -Marthasville,MO

8.0 out of 10, Very Good, (2)
"We enjoyed the property. The decor is great and very clean. Location and hospitality was nice. "
The price is AED 444
AED 580 total
includes taxes & fees
7 May - 8 May
The Daniel Boone Room -Marthasville,MO
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
Terrace/patio

Fish Haus: charming cottage with breathtaking views of the Missouri River!!

10.0 out of 10, Exceptional, (6)
"A lovely cottage overlooking the Missouri- we had a great experience! "
The price is AED 606
AED 838 total
includes taxes & fees
7 May - 8 May
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
1 bedroom, bed sheets

Wine Haus: charming cottage with breathtaking views of the Missouri River!!

2.0 star property
10.0 out of 10, Exceptional, (2)
"Lived the scenery and decor. Hosts were lovely!! Vern nice breakfast!!"
The price is AED 606
AED 827 total
includes taxes & fees
12 May - 13 May
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
Trinity Hill Bed & Breakfast - In Missouri Wine Country
Fridge, microwave, oven, stovetop

Trinity Hill Bed & Breakfast - In Missouri Wine Country

10.0 out of 10, Exceptional, (8)
"Beautiful place. Great breakfast each morning. I highly recommend this property and hosts. "
The price is AED 691
AED 1,224 total
includes taxes & fees
8 May - 9 May
Trinity Hill Bed & Breakfast - In Missouri Wine Country
TheOutPostInn Bed&Breakfast - The Blue Victorian
Aerial view

TheOutPostInn Bed&Breakfast - The Blue Victorian

10.0 out of 10, Exceptional, (3)
"Stayed in Hermann one night and here one night. Great space, comfy bed, quiet area."
The price is AED 400
AED 672 total
includes taxes & fees
7 May - 8 May
TheOutPostInn Bed&Breakfast - The Blue Victorian
The Wineaux! Wine Country charm in Marthasville,MO
Interior

The Wineaux! Wine Country charm in Marthasville,MO

9.2 out of 10, Wonderful, (7)
"We loved the location and historic building there was no breakfast as promised and rooms were not ready when we got there at 4."
The price is AED 562
AED 877 total
includes taxes & fees
8 May - 9 May
The Wineaux! Wine Country charm in Marthasville,MO
The Cyclist! Katy Trail comfort in Marthasville,MO
Interior

The Cyclist! Katy Trail comfort in Marthasville,MO

9.8 out of 10, Exceptional, (7)
"Wonderful place to get away to and relax!"
The price is AED 562
AED 877 total
includes taxes & fees
7 May - 8 May
The Cyclist! Katy Trail comfort in Marthasville,MO
TheOutPostInn Bed&Breakfast - The Purple Victorian
1 bedroom, free WiFi, bed sheets

TheOutPostInn Bed&Breakfast - The Purple Victorian

6.0 out of 10, (1)
"It was a small room and had to squeeze between the bed and wall to get in. Almost had to use the foot stool to get in the bed secondary to being so high up and the mattress was extremely firm. The pillows were super soft which did not go with the firm bed, woke up several times in the night to re fluff the pillows and still woke up with a sore neck. The thing that bothered me the most was the curtain in the bathroom was screwed to the wall and you could not close them for privacy. The building...
The price is AED 465
AED 746 total
includes taxes & fees
8 May - 9 May
TheOutPostInn Bed&Breakfast - The Purple Victorian
The Hiding Place B&B
Free daily full breakfast

The Hiding Place B&B

3.0 star property
9.8 out of 10, Exceptional, (25)
"Everything was very nice. We would use again if in the area. "
The Hiding Place B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Defiance

St. Charles 1860's Gem - Sleeps 6!
Fridge, microwave, oven, stovetop

St. Charles 1860's Gem - Sleeps 6!

9.8 out of 10, Exceptional, (94)
"Our second year in a row and we love this place! It is perfect for a girls trip."
The price is AED 422
AED 885 total
includes taxes & fees
12 May - 13 May
St. Charles 1860's Gem - Sleeps 6!
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
Outdoor dining

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10.0 out of 10, Exceptional, (200)
"This property is within easy walking distance to ALL of historic downtown St Charles. It's obvious the owners take great care in keeping The Guest House in perfect condition, with every possible amenity provided. Very comfortable stay. We'll absolutely be back!"
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome
Pool

☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome

9.0 out of 10, Wonderful, (46)
"Everything was perfect. Thank you so much for everything. "
The price is AED 804
AED 1,578 total
includes taxes & fees
7 May - 8 May
☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Searching for B&Bs in Defiance?
If you’re looking for something a little more offbeat than your standard hotel experience, a bed and breakfast could be the perfect alternative for your getaway. When you want to venture out to explore Defiance, consider browsing the exhibits at Historic Daniel Boone Home and Heritage Center.
Are you thinking about a B&B for your stay?
With attentive service, opportunities to socialize with other guests, and of course a full breakfast to start the day, B&Bs all have a one-of-a-kind environment.
What are the best B&Bs in Defiance?
Here is a B&B that guests like in the surrounding area: The Daniel Boone Room -Marthasville,MO: Situated 15.3 mi (24.6 km) from the heart of Defiance.
What's the best time of year to book my B&B in Defiance?
When you’re dreaming of a trip to Defiance, year-round temperatures and rainfall may be important factors to consider. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What is there to do in Defiance?
Spend some time exploring August A. Busch Memorial Conservation Area and Missouri River if you’re hoping to see some of the area’s natural features. You might put Chandler Hill Vineyards and Sugar Creek Winery on your list if you want to see more of the area.
How can I get to and around Defiance?
You can plan your excursions in and around Defiance ahead of time with these transportation options. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) away from the heart of the city. Otherwise, look for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you’d like to venture out around the area, you may want to rent a car for your trip.