Find Resorts & Hotels with Spas in St. Charles, MO

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Pick from 29 St. Charles Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1159)
"Excellent location and well maintained. "
The price is AED 396
AED 447 total
includes taxes & fees
1 Dec - 2 Dec
Embassy Suites by Hilton St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3.0 star property
9.8 out of 10, Exceptional, (1005)
"One of the nicest hotels Ive ever stayed at. Staff is beyond wonderful. The breakfast and dinner is a game changer. Saved us lots of money."
The price is AED 459
AED 532 total
includes taxes & fees
26 Nov - 27 Nov
Drury Plaza Hotel St. Louis St. Charles

Tru by Hilton St. Charles St. Louis, MO

2.5 star property
8.6 out of 10, Excellent, (644)
"Very friendly and helpful staff!"
The price is AED 340
AED 387 total
includes taxes & fees
15 Dec - 16 Dec
Tru by Hilton St. Charles St. Louis, MO

Hampton Inn & Suites St. Charles Old Town Area

2.5 star property
9.2 out of 10, Wonderful, (433)
"Good breakfast "
The price is AED 362
AED 430 total
includes taxes & fees
15 Dec - 16 Dec
Hampton Inn & Suites St. Charles Old Town Area

Best Western Plus The Charles Hotel

3.0 star property
8.0 out of 10, Very Good, (1005)
"Hotel was convenient for our needs and plenty of choices for dining close by."
The price is AED 348
AED 396 total
includes taxes & fees
1 Dec - 2 Dec
Best Western Plus The Charles Hotel

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

2.5 star property
5.8 out of 10, (1033)
"Hotel is economical in need of refurbish and repair but not bad for the price. Location is great, close to the river and historic downtown district. Staff was friendly and helpful. Close to shopping and Basspro."
The price is AED 294
AED 341 total
includes taxes & fees
26 Nov - 27 Nov
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Comfort Suites St Charles - St Louis

2.5 star property
8.6 out of 10, Excellent, (789)
"Great stay! Rooms was spacious and clean. Bed was super comfortable. "
The price is AED 276
AED 311 total
includes taxes & fees
15 Dec - 16 Dec
Comfort Suites St Charles - St Louis

Sleep Inn & Suites

2.5 star property
6.0 out of 10, (428)
"The room was comfortable. The shower was a bit wonky to turn on but we figured it out eventually. Beds were comfortable. The location was a bit noisy until traffic died down."
The price is AED 232
AED 262 total
includes taxes & fees
8 Dec - 9 Dec
Sleep Inn & Suites

WoodSpring Suites St Louis St Charles

2.5 star property
5.4 out of 10, (266)
"Great stay."
The price is AED 261
AED 288 total
includes taxes & fees
26 Nov - 27 Nov
WoodSpring Suites St Louis St Charles

Baymont by Wyndham St. Charles

2.5 star property
8.0 out of 10, Very Good, (972)
"Very good. Comfy bed. Nice bath. "
The price is AED 235
AED 265 total
includes taxes & fees
1 Dec - 2 Dec
Baymont by Wyndham St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 5 restaurants, a casino, a pool, and a 24-hour fitness center. Treat yourself to a facial, body scrub, or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia’s 174 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail, and St Charles Convention Center. If you have some spare time during your trip, you might want to check out Ameristar Casino St. Charles and Fast Lane Classic Cars.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.