Find Resorts & Hotels with Spas in St. Charles, MO

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Pick from 29 St. Charles Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Embassy Suites by Hilton St. Louis St. Charles
Exterior
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
8.8 out of 10, Excellent, (1152)
"Stayed one night. "
The price is AED 465
AED 527 total
includes taxes & fees
25 Nov - 26 Nov
Embassy Suites by Hilton St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
Exterior
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.8 out of 10, Exceptional, (1000)
"Great accomodations and extra perks for the price"
The price is AED 459
AED 532 total
includes taxes & fees
17 Nov - 18 Nov
Drury Plaza Hotel St. Louis St. Charles
Tru by Hilton St. Charles St. Louis, MO
Exterior
Tru by Hilton St. Charles St. Louis, MO
2.5 star property
8.4 out of 10, Very Good, (643)
"Very friendly and helpful staff!"
The price is AED 403
AED 458 total
includes taxes & fees
1 Dec - 2 Dec
Tru by Hilton St. Charles St. Louis, MO
Hampton Inn & Suites St. Charles Old Town Area
Lobby
Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
9.2 out of 10, Wonderful, (431)
"Upon arriving at the hotel, the clerk was very friendly & accommodating and check-in was quick and smooth. When we got to our room, there was an issue with the a/c, so the clerk very quickly moved us to another room. When going into the 2nd room, it was 2 full size beds, rather than 1 king bed that we had reserved. The clerk quickly moved us to a 3rd room, and upgraded it to a King Suite for the trouble. The room was Very Nice & Comfortable, and was Perfect for our needs. The Continental...
The price is AED 388
AED 457 total
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn & Suites St. Charles Old Town Area
Best Western Plus The Charles Hotel
Exterior
Best Western Plus The Charles Hotel
3.0 star property
8.0 out of 10, Very Good, (1001)
"Always a great stay here. I stay 2 times a year great staff. Great breakfast. "
The price is AED 348
AED 396 total
includes taxes & fees
18 Nov - 19 Nov
Best Western Plus The Charles Hotel
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Exterior
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
5.8 out of 10, (1002)
"Hotel is economical in need of refurbish and repair but not bad for the price. Location is great, close to the river and historic downtown district. Staff was friendly and helpful. Close to shopping and Basspro."
The price is AED 294
AED 341 total
includes taxes & fees
17 Nov - 18 Nov
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Comfort Suites St Charles - St Louis
Pool
Comfort Suites St Charles - St Louis
2.5 star property
8.6 out of 10, Excellent, (786)
"Stay here frequently- dependable, good stay every time "
The price is AED 276
AED 311 total
includes taxes & fees
27 Nov - 28 Nov
Comfort Suites St Charles - St Louis
Sleep Inn & Suites
Exterior
Sleep Inn & Suites
2.5 star property
6.0 out of 10, (426)
"The room was comfortable. The shower was a bit wonky to turn on but we figured it out eventually. Beds were comfortable. The location was a bit noisy until traffic died down."
The price is AED 194
AED 218 total
includes taxes & fees
8 Dec - 9 Dec
Sleep Inn & Suites
WoodSpring Suites St Louis St Charles
Exterior
WoodSpring Suites St Louis St Charles
2.5 star property
5.4 out of 10, (265)
"Great stay."
The price is AED 261
AED 300 total
includes taxes & fees
17 Nov - 18 Nov
WoodSpring Suites St Louis St Charles
Baymont by Wyndham St. Charles
Room
Baymont by Wyndham St. Charles
2.5 star property
8.0 out of 10, Very Good, (965)
"My bed is clean and comfy! I always love that hotel use all white beddings and overall the room is clean and tidy. The area in St Charles is what makes me decide to stay here. Very safe and quiet. "
The price is AED 250
AED 281 total
includes taxes & fees
19 Nov - 20 Nov
Baymont by Wyndham St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 5 restaurants, a casino, a pool, and a 24-hour fitness center. Treat yourself to a facial, body scrub, or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia’s 174 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail, and St Charles Convention Center. If you have some spare time during your trip, you might want to check out Ameristar Casino St. Charles and Fast Lane Classic Cars.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.