Find Business Hotels in St. Charles, MO
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on St. Charles Business Hotels
Compare St. Charles Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.
![Exterior](https://images.trvl-media.com/lodging/2000000/1950000/1942000/1941935/351058e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Research Park Inn St Louis West – Chesterfield
Research Park Inn St Louis West – Chesterfield
5.8 out of 10, (1006)
![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40300/40297/d2355685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Best Western Plus The Charles Hotel
Best Western Plus The Charles Hotel
8.0 out of 10, Very Good, (1005)
The price is AED 336
AED 389 total
includes taxes & fees
23 Feb - 24 Feb
![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/235ec798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
8.8 out of 10, Excellent, (1168)
The price is AED 509
AED 585 total
includes taxes & fees
23 Feb - 24 Feb
![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/373b2a05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
9.4 out of 10, Exceptional, (1002)
The price is AED 450
AED 517 total
includes taxes & fees
23 Feb - 24 Feb
![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/50bb23c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1007)
The price is AED 621
AED 787 total
includes taxes & fees
18 Feb - 19 Feb
![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/b0fa7fd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
8.2 out of 10, Very Good, (1000)
The price is AED 320
AED 368 total
includes taxes & fees
23 Feb - 24 Feb
![Exterior](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/025b7f34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
5.8 out of 10, (1000)
The price is AED 294
AED 341 total
includes taxes & fees
18 Feb - 19 Feb
![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/e3f3f6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
8.6 out of 10, Excellent, (845)
The price is AED 293
AED 337 total
includes taxes & fees
23 Feb - 24 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about St. Charles
Find out more about St. Charles
Recent reviews of St. Charles hotels
Recent reviews of St. Charles hotels
![Pear Tree Inn St. Louis Airport](http://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg)
Pear Tree Inn St. Louis Airport
5/5 Excellent
"Friendly staff"
A verified traveler stayed at Pear Tree Inn St. Louis Airport
Posted 14 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Business Hotels
Find More Hotels near St. Charles
More Hotel Options in St. Charles
- Adventure Hotels in St. Charles
- Casinos in St. Charles
- Cheap Hotels in St. Charles
- Family Hotels in St. Charles
- Golf Hotels in St. Charles
- Historic Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotel with a Concierge in St. Charles
- Hotels with Bars in St. Charles
- Hotels with Free Parking in St. Charles
- Hotels with Hot Tubs in St. Charles
- Hotels with WiFi in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Hotels with smoking rooms in St. Charles
- Luxury Hotels in St. Charles
- Pet-friendly Hotels in St. Charles
- Resorts & Hotels with Spas in St. Charles
- Romantic Hotels in St. Charles
- Shopping Hotels in St. Charles
- Winery Hotels in St. Charles
Hotels near popular St. Louis Attractions
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Katy Trail
- Hotels near Fast Lane Classic Cars
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
St. Charles Hotels by Star Rating
Explore more hotels
- Clayton Plaza Hotel & Extended Stay
- River City Casino & Hotel
- 21C Museum Hotel St Louis
- Embassy Suites by Hilton St. Louis Downtown
- Pear Tree Inn St. Louis Airport
- The Wildwood Hotel
- Moonrise Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Live by Loews - St.Louis
- Holiday Inn St. Louis - Downtown Conv Ctr, an IHG Hotel
- Best Western St. Louis-Kirkwood Route 66
- The Last Hotel
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Angad Arts Hotel
- Drury Inn & Suites St. Louis Union Station
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Drury Inn & Suites St. Louis Airport
- Hilton Pennywell St. Louis at the Arch
- Renaissance St. Louis Airport Hotel
- Pear Tree Inn St. Louis Near Union Station